235 related articles for article (PubMed ID: 26526067)
1. Organic Anion Transporting Polypeptide (OATP)2B1 Contributes to Gastrointestinal Toxicity of Anticancer Drug SN-38, Active Metabolite of Irinotecan Hydrochloride.
Fujita D; Saito Y; Nakanishi T; Tamai I
Drug Metab Dispos; 2016 Jan; 44(1):1-7. PubMed ID: 26526067
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of intestinal microflora beta-glucuronidase modifies the distribution of the active metabolite of the antitumor agent, irinotecan hydrochloride (CPT-11) in rats.
Takasuna K; Hagiwara T; Hirohashi M; Kato M; Nomura M; Nagai E; Yokoi T; Kamataki T
Cancer Chemother Pharmacol; 1998; 42(4):280-6. PubMed ID: 9744772
[TBL] [Abstract][Full Text] [Related]
3. Protective effects of kampo medicines and baicalin against intestinal toxicity of a new anticancer camptothecin derivative, irinotecan hydrochloride (CPT-11), in rats.
Takasuna K; Kasai Y; Kitano Y; Mori K; Kobayashi R; Hagiwara T; Kakihata K; Hirohashi M; Nomura M; Nagai E
Jpn J Cancer Res; 1995 Oct; 86(10):978-84. PubMed ID: 7493918
[TBL] [Abstract][Full Text] [Related]
4. Long-lasting inhibitory effect of apple and orange juices, but not grapefruit juice, on OATP2B1-mediated drug absorption.
Shirasaka Y; Shichiri M; Murata Y; Mori T; Nakanishi T; Tamai I
Drug Metab Dispos; 2013 Mar; 41(3):615-21. PubMed ID: 23264447
[TBL] [Abstract][Full Text] [Related]
5. Optimal antidiarrhea treatment for antitumor agent irinotecan hydrochloride (CPT-11)-induced delayed diarrhea.
Takasuna K; Hagiwara T; Watanabe K; Onose S; Yoshida S; Kumazawa E; Nagai E; Kamataki T
Cancer Chemother Pharmacol; 2006 Oct; 58(4):494-503. PubMed ID: 16437251
[TBL] [Abstract][Full Text] [Related]
6. Effects of one-time apple juice ingestion on the pharmacokinetics of fexofenadine enantiomers.
Akamine Y; Miura M; Komori H; Saito S; Kusuhara H; Tamai I; Ieiri I; Uno T; Yasui-Furukori N
Eur J Clin Pharmacol; 2014 Sep; 70(9):1087-95. PubMed ID: 24903351
[TBL] [Abstract][Full Text] [Related]
7. Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions.
Shirasaka Y; Shichiri M; Mori T; Nakanishi T; Tamai I
J Pharm Sci; 2013 Sep; 102(9):3418-26. PubMed ID: 23794501
[TBL] [Abstract][Full Text] [Related]
8. Streptomycin alleviates irinotecan-induced delayed-onset diarrhea in rats by a mechanism other than inhibition of β-glucuronidase activity in intestinal lumen.
Kurita A; Kado S; Matsumoto T; Asakawa N; Kaneda N; Kato I; Uchida K; Onoue M; Yokokura T
Cancer Chemother Pharmacol; 2011 Jan; 67(1):201-13. PubMed ID: 20354702
[TBL] [Abstract][Full Text] [Related]
9. Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms.
Nozawa T; Minami H; Sugiura S; Tsuji A; Tamai I
Drug Metab Dispos; 2005 Mar; 33(3):434-9. PubMed ID: 15608127
[TBL] [Abstract][Full Text] [Related]
10. Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1.
Medwid S; Li MMJ; Knauer MJ; Lin K; Mansell SE; Schmerk CL; Zhu C; Griffin KE; Yousif MD; Dresser GK; Schwarz UI; Kim RB; Tirona RG
Drug Metab Dispos; 2019 Aug; 47(8):832-842. PubMed ID: 31123035
[TBL] [Abstract][Full Text] [Related]
11. Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions.
Shirasaka Y; Shichiri M; Mori T; Nakanishi T; Tamai I
J Pharm Sci; 2013 Jan; 102(1):280-8. PubMed ID: 23132664
[TBL] [Abstract][Full Text] [Related]
12. Quantitative Investigation of Irinotecan Metabolism, Transport, and Gut Microbiome Activation.
Parvez MM; Basit A; Jariwala PB; Gáborik Z; Kis E; Heyward S; Redinbo MR; Prasad B
Drug Metab Dispos; 2021 Aug; 49(8):683-693. PubMed ID: 34074730
[TBL] [Abstract][Full Text] [Related]
13. Involvement of beta-glucuronidase in intestinal microflora in the intestinal toxicity of the antitumor camptothecin derivative irinotecan hydrochloride (CPT-11) in rats.
Takasuna K; Hagiwara T; Hirohashi M; Kato M; Nomura M; Nagai E; Yokoi T; Kamataki T
Cancer Res; 1996 Aug; 56(16):3752-7. PubMed ID: 8706020
[TBL] [Abstract][Full Text] [Related]
14. Pharmacokinetic mechanisms for reduced toxicity of irinotecan by coadministered thalidomide.
Yang XX; Hu ZP; Chan SY; Duan W; Ho PC; Boelsterli UA; Ng KY; Chan E; Bian JS; Chen YZ; Huang M; Zhou SF
Curr Drug Metab; 2006 May; 7(4):431-55. PubMed ID: 16724931
[TBL] [Abstract][Full Text] [Related]
15. Pharmacological inhibition of bacterial β-glucuronidase prevents irinotecan-induced diarrhea without impairing its antitumor efficacy in vivo.
Cheng KW; Tseng CH; Tzeng CC; Leu YL; Cheng TC; Wang JY; Chang JM; Lu YC; Cheng CM; Chen IJ; Cheng YA; Chen YL; Cheng TL
Pharmacol Res; 2019 Jan; 139():41-49. PubMed ID: 30391354
[TBL] [Abstract][Full Text] [Related]
16. Metabolism of irinotecan and its active metabolite SN-38 by intestinal microflora in rats.
Yamamoto M; Kurita A; Asahara T; Takakura A; Katono K; Iwasaki M; Ryuge S; Wada M; Onoda S; Yanaihara T; Yokoba M; Mitsufuji H; Nishii Y; Fukui T; Masuda N
Oncol Rep; 2008 Oct; 20(4):727-30. PubMed ID: 18813810
[TBL] [Abstract][Full Text] [Related]
17. Intestinal Absorption of Alogliptin Is Mediated by a Fruit-Juice-Sensitive Transporter.
Morimoto K; Sasaki M; Oikawa E; Abe M; Kikuchi T; Ishii M; Ogihara T; Tomita M
Biol Pharm Bull; 2021; 44(5):653-658. PubMed ID: 33952821
[TBL] [Abstract][Full Text] [Related]
18. Opioid-induced microbial dysbiosis disrupts irinotecan (CPT-11) metabolism and increases gastrointestinal toxicity in a murine model.
Meng J; Abu YF; Zhang Y; Zhou Y; Xie Y; Yan Y; Tao J; Ramakrishnan S; Chen C; Roy S
Br J Pharmacol; 2023 May; 180(10):1362-1378. PubMed ID: 36562107
[TBL] [Abstract][Full Text] [Related]
19. New approaches to prevent intestinal toxicity of irinotecan-based regimens.
Alimonti A; Gelibter A; Pavese I; Satta F; Cognetti F; Ferretti G; Rasio D; Vecchione A; Di Palma M
Cancer Treat Rev; 2004 Oct; 30(6):555-62. PubMed ID: 15325035
[TBL] [Abstract][Full Text] [Related]
20. Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.
Dresser GK; Bailey DG; Leake BF; Schwarz UI; Dawson PA; Freeman DJ; Kim RB
Clin Pharmacol Ther; 2002 Jan; 71(1):11-20. PubMed ID: 11823753
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
