BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 26527528)

  • 1. The K167I variant of DNA polymerase β that is found in Esophageal Carcinoma patients impairs polymerase activity and BER.
    Wang Y; Zang W; Du Y; Chen X; Zhao G
    Sci Rep; 2015 Nov; 5():15986. PubMed ID: 26527528
    [TBL] [Abstract][Full Text] [Related]  

  • 2. R152C DNA Pol β mutation impairs base excision repair and induces cellular transformation.
    Zhou T; Pan F; Cao Y; Han Y; Zhao J; Sun H; Zhou X; Wu X; He L; Hu Z; Chen H; Shen B; Guo Z
    Oncotarget; 2016 Feb; 7(6):6902-15. PubMed ID: 26760506
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA polymerase β-dependent cell survival independent of XRCC1 expression.
    Horton JK; Gassman NR; Dunigan BD; Stefanick DF; Wilson SH
    DNA Repair (Amst); 2015 Feb; 26():23-9. PubMed ID: 25541391
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The E295K DNA polymerase beta gastric cancer-associated variant interferes with base excision repair and induces cellular transformation.
    Lang T; Dalal S; Chikova A; DiMaio D; Sweasy JB
    Mol Cell Biol; 2007 Aug; 27(15):5587-96. PubMed ID: 17526740
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Research progress on DNA polymerase beta and genetic instability].
    Wu M; Zhang Z
    Wei Sheng Yan Jiu; 2009 Sep; 38(5):637-40. PubMed ID: 19877532
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Base excision repair deficiency caused by polymerase beta haploinsufficiency: accelerated DNA damage and increased mutational response to carcinogens.
    Cabelof DC; Guo Z; Raffoul JJ; Sobol RW; Wilson SH; Richardson A; Heydari AR
    Cancer Res; 2003 Sep; 63(18):5799-807. PubMed ID: 14522902
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 'Knock down' of DNA polymerase beta by RNA interference: recapitulation of null phenotype.
    Polosina YY; Rosenquist TA; Grollman AP; Miller H
    DNA Repair (Amst); 2004 Nov; 3(11):1469-74. PubMed ID: 15380102
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Involvement of DNA polymerase beta in repairing oxidative damages induced by antitumor drug adriamycin.
    Liu S; Wu M; Zhang Z
    Toxicol Appl Pharmacol; 2010 Aug; 246(3):163-70. PubMed ID: 20510258
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The lyase activity of the DNA repair protein beta-polymerase protects from DNA-damage-induced cytotoxicity.
    Sobol RW; Prasad R; Evenski A; Baker A; Yang XP; Horton JK; Wilson SH
    Nature; 2000 Jun; 405(6788):807-10. PubMed ID: 10866204
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modulation of trinucleotide repeat instability by DNA polymerase β polymorphic variant R137Q.
    Ren Y; Lai Y; Laverde EE; Lei R; Rein HL; Liu Y
    PLoS One; 2017; 12(5):e0177299. PubMed ID: 28475635
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gastric cancer associated variant of DNA polymerase beta (Leu22Pro) promotes DNA replication associated double strand breaks.
    Rozacky J; Nemec AA; Sweasy JB; Kidane D
    Oncotarget; 2015 Sep; 6(27):24474-87. PubMed ID: 26090616
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity.
    Guo Z; Zheng L; Dai H; Zhou M; Xu H; Shen B
    Nucleic Acids Res; 2009 Jun; 37(10):3431-41. PubMed ID: 19336415
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA polymerases beta and lambda mediate overlapping and independent roles in base excision repair in mouse embryonic fibroblasts.
    Braithwaite EK; Kedar PS; Stumpo DJ; Bertocci B; Freedman JH; Samson LD; Wilson SH
    PLoS One; 2010 Aug; 5(8):e12229. PubMed ID: 20805875
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Implication of p53 in base excision DNA repair: in vivo evidence.
    Seo YR; Fishel ML; Amundson S; Kelley MR; Smith ML
    Oncogene; 2002 Jan; 21(5):731-7. PubMed ID: 11850801
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synergistic Effects of an Irreversible DNA Polymerase Inhibitor and DNA Damaging Agents on HeLa Cells.
    Paul R; Banerjee S; Greenberg MM
    ACS Chem Biol; 2017 Jun; 12(6):1576-1583. PubMed ID: 28459532
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Y265C DNA polymerase beta knockin mice survive past birth and accumulate base excision repair intermediate substrates.
    Senejani AG; Dalal S; Liu Y; Nottoli TP; McGrath JM; Clairmont CS; Sweasy JB
    Proc Natl Acad Sci U S A; 2012 Apr; 109(17):6632-7. PubMed ID: 22493258
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Colon cancer-associated DNA polymerase β variant induces genomic instability and cellular transformation.
    Nemec AA; Donigan KA; Murphy DL; Jaeger J; Sweasy JB
    J Biol Chem; 2012 Jul; 287(28):23840-9. PubMed ID: 22573322
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cellular roles of DNA polymerase beta.
    Ray S; Menezes MR; Senejani A; Sweasy JB
    Yale J Biol Med; 2013 Dec; 86(4):463-9. PubMed ID: 24348210
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hypoxia provokes base excision repair changes and a repair-deficient, mutator phenotype in colorectal cancer cells.
    Chan N; Ali M; McCallum GP; Kumareswaran R; Koritzinsky M; Wouters BG; Wells PG; Gallinger S; Bristow RG
    Mol Cancer Res; 2014 Oct; 12(10):1407-15. PubMed ID: 25030372
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cells deficient in DNA polymerase beta are hypersensitive to alkylating agent-induced apoptosis and chromosomal breakage.
    Ochs K; Sobol RW; Wilson SH; Kaina B
    Cancer Res; 1999 Apr; 59(7):1544-51. PubMed ID: 10197627
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.