Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

694 related articles for article (PubMed ID: 26534963)

  • 1. The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways.
    Kovacevic Z; Menezes SV; Sahni S; Kalinowski DS; Bae DH; Lane DJ; Richardson DR
    J Biol Chem; 2016 Jan; 291(3):1029-52. PubMed ID: 26534963
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling.
    Wangpu X; Lu J; Xi R; Yue F; Sahni S; Park KC; Menezes S; Huang ML; Zheng M; Kovacevic Z; Richardson DR
    Mol Pharmacol; 2016 May; 89(5):521-40. PubMed ID: 26895766
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interplay of the iron-regulated metastasis suppressor NDRG1 with epidermal growth factor receptor (EGFR) and oncogenic signaling.
    Menezes SV; Sahni S; Kovacevic Z; Richardson DR
    J Biol Chem; 2017 Aug; 292(31):12772-12782. PubMed ID: 28615452
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The metastasis suppressor NDRG1 down-regulates the epidermal growth factor receptor via a lysosomal mechanism by up-regulating mitogen-inducible gene 6.
    Menezes SV; Kovacevic Z; Richardson DR
    J Biol Chem; 2019 Mar; 294(11):4045-4064. PubMed ID: 30679310
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Iron chelator-induced up-regulation of Ndrg1 inhibits proliferation and EMT process by targeting Wnt/β-catenin pathway in colon cancer cells.
    Chen Z; Sun J; Li T; Liu Y; Gao S; Zhi X; Zheng M
    Biochem Biophys Res Commun; 2018 Nov; 506(1):114-121. PubMed ID: 30340826
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel Thiosemicarbazones Inhibit Lysine-Rich Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) Coisolated (LYRIC) and the LYRIC-Induced Epithelial-Mesenchymal Transition via Upregulation of N-Myc Downstream-Regulated Gene 1 (NDRG1).
    Xi R; Pun IH; Menezes SV; Fouani L; Kalinowski DS; Huang ML; Zhang X; Richardson DR; Kovacevic Z
    Mol Pharmacol; 2017 May; 91(5):499-517. PubMed ID: 28275050
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells.
    Dixon KM; Lui GY; Kovacevic Z; Zhang D; Yao M; Chen Z; Dong Q; Assinder SJ; Richardson DR
    Br J Cancer; 2013 Feb; 108(2):409-19. PubMed ID: 23287991
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The metastasis suppressor, NDRG1, differentially modulates the endoplasmic reticulum stress response.
    Merlot AM; Porter GM; Sahni S; Lim EG; Peres P; Richardson DR
    Biochim Biophys Acta Mol Basis Dis; 2019 Sep; 1865(9):2094-2110. PubMed ID: 30981813
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The iron-regulated metastasis suppressor NDRG1 targets NEDD4L, PTEN, and SMAD4 and inhibits the PI3K and Ras signaling pathways.
    Kovacevic Z; Chikhani S; Lui GY; Sivagurunathan S; Richardson DR
    Antioxid Redox Signal; 2013 Mar; 18(8):874-87. PubMed ID: 22462691
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Breaking the cycle: Targeting of NDRG1 to inhibit bi-directional oncogenic cross-talk between pancreatic cancer and stroma.
    Geleta B; Park KC; Jansson PJ; Sahni S; Maleki S; Xu Z; Murakami T; Pajic M; Apte MV; Richardson DR; Kovacevic Z
    FASEB J; 2021 Feb; 35(2):e21347. PubMed ID: 33484481
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel thiosemicarbazone iron chelators induce up-regulation and phosphorylation of the metastasis suppressor N-myc down-stream regulated gene 1: a new strategy for the treatment of pancreatic cancer.
    Kovacevic Z; Chikhani S; Lovejoy DB; Richardson DR
    Mol Pharmacol; 2011 Oct; 80(4):598-609. PubMed ID: 21719465
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A new model system identifies epidermal growth factor receptor-human epidermal growth factor receptor 2 (HER2) and HER2-human epidermal growth factor receptor 3 heterodimers as potent inducers of oesophageal epithelial cell invasion.
    Fichter CD; Przypadlo CM; Buck A; Herbener N; Riedel B; Schäfer L; Nakagawa H; Walch A; Reinheckel T; Werner M; Lassmann S
    J Pathol; 2017 Dec; 243(4):481-495. PubMed ID: 28940194
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NDRG1 suppresses basal and hypoxia-induced autophagy at both the initiation and degradation stages and sensitizes pancreatic cancer cells to lysosomal membrane permeabilization.
    Sahni S; Gillson J; Park KC; Chiang S; Leck LYW; Jansson PJ; Richardson DR
    Biochim Biophys Acta Gen Subj; 2020 Aug; 1864(8):129625. PubMed ID: 32335136
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The metastasis suppressor, N-myc downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cells.
    Sahni S; Bae DH; Lane DJ; Kovacevic Z; Kalinowski DS; Jansson PJ; Richardson DR
    J Biol Chem; 2014 Apr; 289(14):9692-709. PubMed ID: 24532803
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The metastasis suppressor, NDRG1, attenuates oncogenic TGF-β and NF-κB signaling to enhance membrane E-cadherin expression in pancreatic cancer cells.
    Menezes SV; Fouani L; Huang MLH; Geleta B; Maleki S; Richardson A; Richardson DR; Kovacevic Z
    Carcinogenesis; 2019 Jul; 40(6):805-818. PubMed ID: 30561520
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1).
    Chen Z; Zhang D; Yue F; Zheng M; Kovacevic Z; Richardson DR
    J Biol Chem; 2012 May; 287(21):17016-17028. PubMed ID: 22453918
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting the metastasis suppressor, NDRG1, using novel iron chelators: regulation of stress fiber-mediated tumor cell migration via modulation of the ROCK1/pMLC2 signaling pathway.
    Sun J; Zhang D; Zheng Y; Zhao Q; Zheng M; Kovacevic Z; Richardson DR
    Mol Pharmacol; 2013 Feb; 83(2):454-69. PubMed ID: 23188716
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy.
    Fang BA; Kovačević Ž; Park KC; Kalinowski DS; Jansson PJ; Lane DJ; Sahni S; Richardson DR
    Biochim Biophys Acta; 2014 Jan; 1845(1):1-19. PubMed ID: 24269900
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thiosemicarbazones suppress expression of the c-Met oncogene by mechanisms involving lysosomal degradation and intracellular shedding.
    Park KC; Geleta B; Leck LYW; Paluncic J; Chiang S; Jansson PJ; Kovacevic Z; Richardson DR
    J Biol Chem; 2020 Jan; 295(2):481-503. PubMed ID: 31744884
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacological targeting and the diverse functions of the metastasis suppressor, NDRG1, in cancer.
    Park KC; Paluncic J; Kovacevic Z; Richardson DR
    Free Radic Biol Med; 2020 Sep; 157():154-175. PubMed ID: 31132412
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 35.