These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

713 related articles for article (PubMed ID: 26534963)

  • 1. The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways.
    Kovacevic Z; Menezes SV; Sahni S; Kalinowski DS; Bae DH; Lane DJ; Richardson DR
    J Biol Chem; 2016 Jan; 291(3):1029-52. PubMed ID: 26534963
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling.
    Wangpu X; Lu J; Xi R; Yue F; Sahni S; Park KC; Menezes S; Huang ML; Zheng M; Kovacevic Z; Richardson DR
    Mol Pharmacol; 2016 May; 89(5):521-40. PubMed ID: 26895766
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interplay of the iron-regulated metastasis suppressor NDRG1 with epidermal growth factor receptor (EGFR) and oncogenic signaling.
    Menezes SV; Sahni S; Kovacevic Z; Richardson DR
    J Biol Chem; 2017 Aug; 292(31):12772-12782. PubMed ID: 28615452
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The metastasis suppressor NDRG1 down-regulates the epidermal growth factor receptor via a lysosomal mechanism by up-regulating mitogen-inducible gene 6.
    Menezes SV; Kovacevic Z; Richardson DR
    J Biol Chem; 2019 Mar; 294(11):4045-4064. PubMed ID: 30679310
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Iron chelator-induced up-regulation of Ndrg1 inhibits proliferation and EMT process by targeting Wnt/β-catenin pathway in colon cancer cells.
    Chen Z; Sun J; Li T; Liu Y; Gao S; Zhi X; Zheng M
    Biochem Biophys Res Commun; 2018 Nov; 506(1):114-121. PubMed ID: 30340826
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel Thiosemicarbazones Inhibit Lysine-Rich Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) Coisolated (LYRIC) and the LYRIC-Induced Epithelial-Mesenchymal Transition via Upregulation of N-Myc Downstream-Regulated Gene 1 (NDRG1).
    Xi R; Pun IH; Menezes SV; Fouani L; Kalinowski DS; Huang ML; Zhang X; Richardson DR; Kovacevic Z
    Mol Pharmacol; 2017 May; 91(5):499-517. PubMed ID: 28275050
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells.
    Dixon KM; Lui GY; Kovacevic Z; Zhang D; Yao M; Chen Z; Dong Q; Assinder SJ; Richardson DR
    Br J Cancer; 2013 Feb; 108(2):409-19. PubMed ID: 23287991
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The metastasis suppressor, NDRG1, differentially modulates the endoplasmic reticulum stress response.
    Merlot AM; Porter GM; Sahni S; Lim EG; Peres P; Richardson DR
    Biochim Biophys Acta Mol Basis Dis; 2019 Sep; 1865(9):2094-2110. PubMed ID: 30981813
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The iron-regulated metastasis suppressor NDRG1 targets NEDD4L, PTEN, and SMAD4 and inhibits the PI3K and Ras signaling pathways.
    Kovacevic Z; Chikhani S; Lui GY; Sivagurunathan S; Richardson DR
    Antioxid Redox Signal; 2013 Mar; 18(8):874-87. PubMed ID: 22462691
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Breaking the cycle: Targeting of NDRG1 to inhibit bi-directional oncogenic cross-talk between pancreatic cancer and stroma.
    Geleta B; Park KC; Jansson PJ; Sahni S; Maleki S; Xu Z; Murakami T; Pajic M; Apte MV; Richardson DR; Kovacevic Z
    FASEB J; 2021 Feb; 35(2):e21347. PubMed ID: 33484481
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel thiosemicarbazone iron chelators induce up-regulation and phosphorylation of the metastasis suppressor N-myc down-stream regulated gene 1: a new strategy for the treatment of pancreatic cancer.
    Kovacevic Z; Chikhani S; Lovejoy DB; Richardson DR
    Mol Pharmacol; 2011 Oct; 80(4):598-609. PubMed ID: 21719465
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A new model system identifies epidermal growth factor receptor-human epidermal growth factor receptor 2 (HER2) and HER2-human epidermal growth factor receptor 3 heterodimers as potent inducers of oesophageal epithelial cell invasion.
    Fichter CD; Przypadlo CM; Buck A; Herbener N; Riedel B; Schäfer L; Nakagawa H; Walch A; Reinheckel T; Werner M; Lassmann S
    J Pathol; 2017 Dec; 243(4):481-495. PubMed ID: 28940194
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NDRG1 suppresses basal and hypoxia-induced autophagy at both the initiation and degradation stages and sensitizes pancreatic cancer cells to lysosomal membrane permeabilization.
    Sahni S; Gillson J; Park KC; Chiang S; Leck LYW; Jansson PJ; Richardson DR
    Biochim Biophys Acta Gen Subj; 2020 Aug; 1864(8):129625. PubMed ID: 32335136
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The metastasis suppressor, N-myc downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cells.
    Sahni S; Bae DH; Lane DJ; Kovacevic Z; Kalinowski DS; Jansson PJ; Richardson DR
    J Biol Chem; 2014 Apr; 289(14):9692-709. PubMed ID: 24532803
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The metastasis suppressor, NDRG1, attenuates oncogenic TGF-β and NF-κB signaling to enhance membrane E-cadherin expression in pancreatic cancer cells.
    Menezes SV; Fouani L; Huang MLH; Geleta B; Maleki S; Richardson A; Richardson DR; Kovacevic Z
    Carcinogenesis; 2019 Jul; 40(6):805-818. PubMed ID: 30561520
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1).
    Chen Z; Zhang D; Yue F; Zheng M; Kovacevic Z; Richardson DR
    J Biol Chem; 2012 May; 287(21):17016-17028. PubMed ID: 22453918
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting the metastasis suppressor, NDRG1, using novel iron chelators: regulation of stress fiber-mediated tumor cell migration via modulation of the ROCK1/pMLC2 signaling pathway.
    Sun J; Zhang D; Zheng Y; Zhao Q; Zheng M; Kovacevic Z; Richardson DR
    Mol Pharmacol; 2013 Feb; 83(2):454-69. PubMed ID: 23188716
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy.
    Fang BA; Kovačević Ž; Park KC; Kalinowski DS; Jansson PJ; Lane DJ; Sahni S; Richardson DR
    Biochim Biophys Acta; 2014 Jan; 1845(1):1-19. PubMed ID: 24269900
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thiosemicarbazones suppress expression of the c-Met oncogene by mechanisms involving lysosomal degradation and intracellular shedding.
    Park KC; Geleta B; Leck LYW; Paluncic J; Chiang S; Jansson PJ; Kovacevic Z; Richardson DR
    J Biol Chem; 2020 Jan; 295(2):481-503. PubMed ID: 31744884
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacological targeting and the diverse functions of the metastasis suppressor, NDRG1, in cancer.
    Park KC; Paluncic J; Kovacevic Z; Richardson DR
    Free Radic Biol Med; 2020 Sep; 157():154-175. PubMed ID: 31132412
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 36.