176 related articles for article (PubMed ID: 26537174)
1. A study on the AMACR catalysed elimination reaction and its application to inhibitor testing.
Yevglevskis M; Lee GL; Sun J; Zhou S; Sun X; Kociok-Köhn G; James TD; Woodman TJ; Lloyd MD
Org Biomol Chem; 2016 Jan; 14(2):612-622. PubMed ID: 26537174
[TBL] [Abstract][Full Text] [Related]
2. The perils of rational design--unexpected irreversible elimination of fluoride from 3-fluoro-2-methylacyl-CoA esters catalysed by α-methylacyl-CoA racemase (AMACR; P504S).
Yevglevskis M; Lee GL; Threadgill MD; Woodman TJ; Lloyd MD
Chem Commun (Camb); 2014 Nov; 50(91):14164-6. PubMed ID: 25277991
[TBL] [Abstract][Full Text] [Related]
3. Structure-activity relationships of rationally designed AMACR 1A inhibitors.
Yevglevskis M; Lee GL; Nathubhai A; Petrova YD; James TD; Threadgill MD; Woodman TJ; Lloyd MD
Bioorg Chem; 2018 Sep; 79():145-154. PubMed ID: 29751320
[TBL] [Abstract][Full Text] [Related]
4. Identification of novel small-molecule inhibitors of α-methylacyl-CoA racemase (AMACR; P504S) and structure-activity relationships.
Petrova YD; Wadda K; Nathubhai A; Yevglevskis M; Mitchell PJ; James TD; Threadgill MD; Woodman TJ; Lloyd MD
Bioorg Chem; 2019 Nov; 92():103264. PubMed ID: 31536955
[TBL] [Abstract][Full Text] [Related]
5. Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents.
Yevglevskis M; Nathubhai A; Wadda K; Lee GL; Al-Rawi S; Jiao T; Mitchell PJ; James TD; Threadgill MD; Woodman TJ; Lloyd MD
Bioorg Chem; 2019 Nov; 92():103263. PubMed ID: 31536953
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and use of isotope-labelled substrates for a mechanistic study on human alpha-methylacyl-CoA racemase 1A (AMACR; P504S).
Darley DJ; Butler DS; Prideaux SJ; Thornton TW; Wilson AD; Woodman TJ; Threadgill MD; Lloyd MD
Org Biomol Chem; 2009 Feb; 7(3):543-52. PubMed ID: 19156321
[TBL] [Abstract][Full Text] [Related]
7. Unexpected stereoselective exchange of straight-chain fatty acyl-CoA alpha-protons by human alpha-methylacyl-CoA racemase 1A (P504S).
Sattar FA; Darley DJ; Politano F; Woodman TJ; Threadgill MD; Lloyd MD
Chem Commun (Camb); 2010 May; 46(19):3348-50. PubMed ID: 20442897
[TBL] [Abstract][Full Text] [Related]
8. A novel colorimetric assay for α-methylacyl-CoA racemase 1A (AMACR; P504S) utilizing the elimination of 2,4-dinitrophenolate.
Yevglevskis M; Lee GL; Nathubhai A; Petrova YD; James TD; Threadgill MD; Woodman TJ; Lloyd MD
Chem Commun (Camb); 2017 May; 53(37):5087-5090. PubMed ID: 28338138
[TBL] [Abstract][Full Text] [Related]
9. Analysis of enzyme reactions using NMR techniques: A case study with α-methylacyl-CoA racemase (AMACR).
Woodman TJ; Lloyd MD
Methods Enzymol; 2023; 690():159-209. PubMed ID: 37858529
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of human α-methylacyl CoA racemase (AMACR): a target for prostate cancer.
Carnell AJ; Kirk R; Smith M; McKenna S; Lian LY; Gibson R
ChemMedChem; 2013 Oct; 8(10):1643-7. PubMed ID: 23929631
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, and in vitro testing of alpha-methylacyl-CoA racemase inhibitors.
Carnell AJ; Hale I; Denis S; Wanders RJ; Isaacs WB; Wilson BA; Ferdinandusse S
J Med Chem; 2007 May; 50(11):2700-7. PubMed ID: 17477519
[TBL] [Abstract][Full Text] [Related]
12. α-Methylacyl-CoA racemase (AMACR): metabolic enzyme, drug metabolizer and cancer marker P504S.
Lloyd MD; Yevglevskis M; Lee GL; Wood PJ; Threadgill MD; Woodman TJ
Prog Lipid Res; 2013 Apr; 52(2):220-30. PubMed ID: 23376124
[TBL] [Abstract][Full Text] [Related]
13. High-throughput screen identifies novel inhibitors of cancer biomarker α-methylacyl coenzyme A racemase (AMACR/P504S).
Wilson BA; Wang H; Nacev BA; Mease RC; Liu JO; Pomper MG; Isaacs WB
Mol Cancer Ther; 2011 May; 10(5):825-38. PubMed ID: 21441411
[TBL] [Abstract][Full Text] [Related]
14. Hydrolysis of ibuprofenoyl-CoA and other 2-APA-CoA esters by human acyl-CoA thioesterases-1 and -2 and their possible role in the chiral inversion of profens.
Qu X; Allan A; Chui G; Hutchings TJ; Jiao P; Johnson L; Leung WY; Li PK; Steel GR; Thompson AS; Threadgill MD; Woodman TJ; Lloyd MD
Biochem Pharmacol; 2013 Dec; 86(11):1621-5. PubMed ID: 24041740
[TBL] [Abstract][Full Text] [Related]
15. Potent dialkyl substrate-product analogue inhibitors and inactivators of α-methylacyl-coenzyme A racemase from Mycobacterium tuberculosis by rational design.
Pal M; Easton NM; Yaphe H; Bearne SL
Bioorg Chem; 2018 Apr; 77():640-650. PubMed ID: 29502025
[TBL] [Abstract][Full Text] [Related]
16. Trifluoroibuprofen inhibits α-methylacyl coenzyme A racemase (AMACR/P504S), reduces cancer cell proliferation and inhibits in vivo tumor growth in aggressive prostate cancer models.
Festuccia C; Gravina GL; Mancini A; Muzi P; Cesare ED; Kirk R; Smith M; Hughes S; Gibson R; Lian LY; Ricevuto E; Carnell AJ
Anticancer Agents Med Chem; 2014; 14(7):1031-41. PubMed ID: 24712326
[TBL] [Abstract][Full Text] [Related]
17. New molecular markers for prostate tumor imaging: a study on 2-methylene substituted fatty acids as new AMACR inhibitors.
Morgenroth A; Urusova EA; Dinger C; Al-Momani E; Kull T; Glatting G; Frauendorf H; Jahn O; Mottaghy FM; Reske SN; Zlatopolskiy BD
Chemistry; 2011 Aug; 17(36):10144-50. PubMed ID: 21812041
[TBL] [Abstract][Full Text] [Related]
18. Chiral inversion of 2-arylpropionyl-CoA esters by human α-methylacyl-CoA racemase 1A (P504S)--a potential mechanism for the anti-cancer effects of ibuprofen.
Woodman TJ; Wood PJ; Thompson AS; Hutchings TJ; Steel GR; Jiao P; Threadgill MD; Lloyd MD
Chem Commun (Camb); 2011 Jul; 47(26):7332-4. PubMed ID: 21614403
[TBL] [Abstract][Full Text] [Related]
19. A continuous assay for alpha-methylacyl-coenzyme A racemase using circular dichroism.
Ouazia D; Bearne SL
Anal Biochem; 2010 Mar; 398(1):45-51. PubMed ID: 19854148
[TBL] [Abstract][Full Text] [Related]
20. A dietary enzyme: alpha-methylacyl-CoA racemase/P504S is overexpressed in colon carcinoma.
Jiang Z; Fanger GR; Banner BF; Woda BA; Algate P; Dresser K; Xu J; Reed SG; Rock KL; Chu PG
Cancer Detect Prev; 2003; 27(6):422-6. PubMed ID: 14642549
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
