287 related articles for article (PubMed ID: 26537408)
1. Accelerated molecular dynamics simulations of ligand binding to a muscarinic G-protein-coupled receptor.
Kappel K; Miao Y; McCammon JA
Q Rev Biophys; 2015 Nov; 48(4):479-87. PubMed ID: 26537408
[TBL] [Abstract][Full Text] [Related]
2. Graded activation and free energy landscapes of a muscarinic G-protein-coupled receptor.
Miao Y; McCammon JA
Proc Natl Acad Sci U S A; 2016 Oct; 113(43):12162-12167. PubMed ID: 27791003
[TBL] [Abstract][Full Text] [Related]
3. Accelerated structure-based design of chemically diverse allosteric modulators of a muscarinic G protein-coupled receptor.
Miao Y; Goldfeld DA; Moo EV; Sexton PM; Christopoulos A; McCammon JA; Valant C
Proc Natl Acad Sci U S A; 2016 Sep; 113(38):E5675-84. PubMed ID: 27601651
[TBL] [Abstract][Full Text] [Related]
4. Structure and dynamics of the M3 muscarinic acetylcholine receptor.
Kruse AC; Hu J; Pan AC; Arlow DH; Rosenbaum DM; Rosemond E; Green HF; Liu T; Chae PS; Dror RO; Shaw DE; Weis WI; Wess J; Kobilka BK
Nature; 2012 Feb; 482(7386):552-6. PubMed ID: 22358844
[TBL] [Abstract][Full Text] [Related]
5. Mechanism of the G-protein mimetic nanobody binding to a muscarinic G-protein-coupled receptor.
Miao Y; McCammon JA
Proc Natl Acad Sci U S A; 2018 Mar; 115(12):3036-3041. PubMed ID: 29507218
[TBL] [Abstract][Full Text] [Related]
6. Mapping of allosteric druggable sites in activation-associated conformers of the M2 muscarinic receptor.
Miao Y; Nichols SE; McCammon JA
Chem Biol Drug Des; 2014 Feb; 83(2):237-46. PubMed ID: 24112716
[TBL] [Abstract][Full Text] [Related]
7. Second M
Kistemaker LEM; Elzinga CRS; Tautermann CS; Pieper MP; Seeliger D; Alikhil S; Schmidt M; Meurs H; Gosens R
Br J Pharmacol; 2019 Aug; 176(16):2864-2876. PubMed ID: 31077341
[TBL] [Abstract][Full Text] [Related]
8. Allosteric effects of sodium ion binding on activation of the m3 muscarinic g-protein-coupled receptor.
Miao Y; Caliman AD; McCammon JA
Biophys J; 2015 Apr; 108(7):1796-1806. PubMed ID: 25863070
[TBL] [Abstract][Full Text] [Related]
9. Allosteric binding sites on muscarinic acetylcholine receptors.
Wess J
Mol Pharmacol; 2005 Dec; 68(6):1506-9. PubMed ID: 16183853
[TBL] [Abstract][Full Text] [Related]
10. Muscarinic acetylcholine receptor X-ray structures: potential implications for drug development.
Kruse AC; Hu J; Kobilka BK; Wess J
Curr Opin Pharmacol; 2014 Jun; 16():24-30. PubMed ID: 24662799
[TBL] [Abstract][Full Text] [Related]
11. Ligand Binding Ensembles Determine Graded Agonist Efficacies at a G Protein-coupled Receptor.
Bock A; Bermudez M; Krebs F; Matera C; Chirinda B; Sydow D; Dallanoce C; Holzgrabe U; De Amici M; Lohse MJ; Wolber G; Mohr K
J Biol Chem; 2016 Jul; 291(31):16375-89. PubMed ID: 27298318
[TBL] [Abstract][Full Text] [Related]
12. Activation and dynamic network of the M2 muscarinic receptor.
Miao Y; Nichols SE; Gasper PM; Metzger VT; McCammon JA
Proc Natl Acad Sci U S A; 2013 Jul; 110(27):10982-7. PubMed ID: 23781107
[TBL] [Abstract][Full Text] [Related]
13. Application of Mixed-Solvent Molecular Dynamics Simulations for Prediction of Allosteric Sites on G Protein-Coupled Receptors.
Chan WKB; Carlson HA; Traynor JR
Mol Pharmacol; 2023 May; 103(5):274-285. PubMed ID: 36868791
[TBL] [Abstract][Full Text] [Related]
14. The allosteric site regulates the voltage sensitivity of muscarinic receptors.
Hoppe A; Marti-Solano M; Drabek M; Bünemann M; Kolb P; Rinne A
Cell Signal; 2018 Jan; 42():114-126. PubMed ID: 29056499
[TBL] [Abstract][Full Text] [Related]
15. Allosteric small molecules unveil a role of an extracellular E2/transmembrane helix 7 junction for G protein-coupled receptor activation.
Jäger D; Schmalenbach C; Prilla S; Schrobang J; Kebig A; Sennwitz M; Heller E; Tränkle C; Holzgrabe U; Höltje HD; Mohr K
J Biol Chem; 2007 Nov; 282(48):34968-76. PubMed ID: 17890226
[TBL] [Abstract][Full Text] [Related]
16. Allosteric modulation in monomers and oligomers of a G protein-coupled receptor.
Shivnaraine RV; Kelly B; Sankar KS; Redka DS; Han YR; Huang F; Elmslie G; Pinto D; Li Y; Rocheleau JV; Gradinaru CC; Ellis J; Wells JW
Elife; 2016 May; 5():. PubMed ID: 27151542
[TBL] [Abstract][Full Text] [Related]
17. Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs.
Dror RO; Green HF; Valant C; Borhani DW; Valcourt JR; Pan AC; Arlow DH; Canals M; Lane JR; Rahmani R; Baell JB; Sexton PM; Christopoulos A; Shaw DE
Nature; 2013 Nov; 503(7475):295-9. PubMed ID: 24121438
[TBL] [Abstract][Full Text] [Related]
18. Discovery and characterization of orthosteric and allosteric muscarinic M2 acetylcholine receptor ligands by affinity selection-mass spectrometry.
Whitehurst CE; Nazef N; Annis DA; Hou Y; Murphy DM; Spacciapoli P; Yao Z; Ziebell MR; Cheng CC; Shipps GW; Felsch JS; Lau D; Nash HM
J Biomol Screen; 2006 Mar; 11(2):194-207. PubMed ID: 16490772
[TBL] [Abstract][Full Text] [Related]
19. Investigating Small-Molecule Ligand Binding to G Protein-Coupled Receptors with Biased or Unbiased Molecular Dynamics Simulations.
Marino KA; Filizola M
Methods Mol Biol; 2018; 1705():351-364. PubMed ID: 29188572
[TBL] [Abstract][Full Text] [Related]
20. A novel multivalent ligand that bridges the allosteric and orthosteric binding sites of the M2 muscarinic receptor.
Steinfeld T; Mammen M; Smith JA; Wilson RD; Jasper JR
Mol Pharmacol; 2007 Aug; 72(2):291-302. PubMed ID: 17478612
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]