BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 26538519)

  • 1. How Epigallocatechin-3-gallate and Tetracycline Interact with the Josephin Domain of Ataxin-3 and Alter Its Aggregation Mode.
    Bonanomi M; Visentin C; Natalello A; Spinelli M; Vanoni M; Airoldi C; Regonesi ME; Tortora P
    Chemistry; 2015 Dec; 21(50):18383-93. PubMed ID: 26538519
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Epigallocatechin-3-gallate and tetracycline differently affect ataxin-3 fibrillogenesis and reduce toxicity in spinocerebellar ataxia type 3 model.
    Bonanomi M; Natalello A; Visentin C; Pastori V; Penco A; Cornelli G; Colombo G; Malabarba MG; Doglia SM; Relini A; Regonesi ME; Tortora P
    Hum Mol Genet; 2014 Dec; 23(24):6542-52. PubMed ID: 25030034
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Epigallocatechin-3-gallate and related phenol compounds redirect the amyloidogenic aggregation pathway of ataxin-3 towards non-toxic aggregates and prevent toxicity in neural cells and Caenorhabditis elegans animal model.
    Visentin C; Pellistri F; Natalello A; Vertemara J; Bonanomi M; Gatta E; Penco A; Relini A; De Gioia L; Airoldi C; Regonesi ME; Tortora P
    Hum Mol Genet; 2017 Sep; 26(17):3271-3284. PubMed ID: 28633380
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interactions of ataxin-3 with its molecular partners in the protein machinery that sorts protein aggregates to the aggresome.
    Bonanomi M; Mazzucchelli S; D'Urzo A; Nardini M; Konarev PV; Invernizzi G; Svergun DI; Vanoni M; Regonesi ME; Tortora P
    Int J Biochem Cell Biol; 2014 Jun; 51():58-64. PubMed ID: 24685680
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protein Environment: A Crucial Triggering Factor in Josephin Domain Aggregation: The Role of 2,2,2-Trifluoroethanol.
    Visentin C; Navarro S; Grasso G; Regonesi ME; Deriu MA; Tortora P; Ventura S
    Int J Mol Sci; 2018 Jul; 19(8):. PubMed ID: 30042316
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Investigation of the Josephin Domain protein-protein interaction by molecular dynamics.
    Deriu MA; Grasso G; Licandro G; Danani A; Gallo D; Tuszynski JA; Morbiducci U
    PLoS One; 2014; 9(9):e108677. PubMed ID: 25268243
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Methacycline displays a strong efficacy in reducing toxicity in a SCA3 Caenorhabditis elegans model.
    Amigoni L; Airoldi C; Natalello A; Romeo M; Diomede L; Tortora P; Regonesi ME
    Biochim Biophys Acta Gen Subj; 2019 Feb; 1863(2):279-290. PubMed ID: 30420336
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A major role for side-chain polyglutamine hydrogen bonding in irreversible ataxin-3 aggregation.
    Natalello A; Frana AM; Relini A; Apicella A; Invernizzi G; Casari C; Gliozzi A; Doglia SM; Tortora P; Regonesi ME
    PLoS One; 2011 Apr; 6(4):e18789. PubMed ID: 21533208
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The role of the central flexible region on the aggregation and conformational properties of human ataxin-3.
    Santambrogio C; Frana AM; Natalello A; Papaleo E; Regonesi ME; Doglia SM; Tortora P; Invernizzi G; Grandori R
    FEBS J; 2012 Feb; 279(3):451-63. PubMed ID: 22129356
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of the structure and the amyloidogenic properties of the Josephin domain of the polyglutamine-containing protein ataxin-3.
    Masino L; Nicastro G; Menon RP; Dal Piaz F; Calder L; Pastore A
    J Mol Biol; 2004 Dec; 344(4):1021-35. PubMed ID: 15544810
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Destabilization of non-pathological variants of ataxin-3 by metal ions results in aggregation/fibrillogenesis.
    Ricchelli F; Fusi P; Tortora P; Valtorta M; Riva M; Tognon G; Chieregato K; Bolognin S; Zatta P
    Int J Biochem Cell Biol; 2007; 39(5):966-77. PubMed ID: 17300980
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mode of substrate recognition by the Josephin domain of ataxin-3, which has an endo-type deubiquitinase activity.
    Satoh T; Sumiyoshi A; Yagi-Utsumi M; Sakata E; Sasakawa H; Kurimoto E; Yamaguchi Y; Li W; Joazeiro CA; Hirokawa T; Kato K
    FEBS Lett; 2014 Nov; 588(23):4422-30. PubMed ID: 25448680
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A-type dimeric epigallocatechin-3-gallate (EGCG) is a more potent inhibitor against the formation of insulin amyloid fibril than EGCG monomer.
    Nie RZ; Zhu W; Peng JM; Ge ZZ; Li CM
    Biochimie; 2016 Jun; 125():204-12. PubMed ID: 27079519
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Josephin domain-containing proteins from a variety of species are active de-ubiquitination enzymes.
    Tzvetkov N; Breuer P
    Biol Chem; 2007 Sep; 388(9):973-8. PubMed ID: 17696782
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of a novel site of interaction between ataxin-3 and the amyloid aggregation inhibitor polyglutamine binding peptide 1.
    Knight PD; Karamanos TK; Radford SE; Ashcroft AE
    Eur J Mass Spectrom (Chichester); 2018 Feb; 24(1):129-140. PubMed ID: 29334808
    [TBL] [Abstract][Full Text] [Related]  

  • 16. (-)-epigallocatechin-3-gallate inhibits fibrillogenesis of chicken cystatin.
    Wang N; He J; Chang AK; Wang Y; Xu L; Chong X; Lu X; Sun Y; Xia X; Li H; Zhang B; Song Y; Kato A; Jones GW
    J Agric Food Chem; 2015 Feb; 63(5):1347-51. PubMed ID: 25620201
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Natural compounds against neurodegenerative diseases: molecular characterization of the interaction of catechins from green tea with Aβ1-42, PrP106-126, and ataxin-3 oligomers.
    Sironi E; Colombo L; Lompo A; Messa M; Bonanomi M; Regonesi ME; Salmona M; Airoldi C
    Chemistry; 2014 Oct; 20(42):13793-800. PubMed ID: 25179684
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Examination of Ataxin-3 (atx-3) Aggregation by Structural Mass Spectrometry Techniques: A Rationale for Expedited Aggregation upon Polyglutamine (polyQ) Expansion.
    Scarff CA; Almeida B; Fraga J; Macedo-Ribeiro S; Radford SE; Ashcroft AE
    Mol Cell Proteomics; 2015 May; 14(5):1241-53. PubMed ID: 25700012
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Josephin Domain Structural Conformations Explored by Metadynamics in Essential Coordinates.
    Deriu MA; Grasso G; Tuszynski JA; Gallo D; Morbiducci U; Danani A
    PLoS Comput Biol; 2016 Jan; 12(1):e1004699. PubMed ID: 26745628
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The conformational ensemble of the disordered and aggregation-protective 182-291 region of ataxin-3.
    Invernizzi G; Lambrughi M; Regonesi ME; Tortora P; Papaleo E
    Biochim Biophys Acta; 2013 Nov; 1830(11):5236-47. PubMed ID: 23891935
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.