BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 26546739)

  • 1. A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition.
    Stockklausner C; Raffel S; Klermund J; Bandapalli OR; Beier F; Brümmendorf TH; Bürger F; Sauer SW; Hoffmann GF; Lorenz H; Tagliaferri L; Nowak D; Hofmann WK; Buergermeister R; Kerber C; Rausch T; Korbel JO; Luke B; Trumpp A; Kulozik AE
    Aging (Albany NY); 2015 Nov; 7(11):911-27. PubMed ID: 26546739
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparable Effects of the Androgen Derivatives Danazol, Oxymetholone and Nandrolone on Telomerase Activity in Human Primary Hematopoietic Cells from Patients with Dyskeratosis Congenita.
    Vieri M; Kirschner M; Tometten M; Abels A; Rolles B; Isfort S; Panse J; Brümmendorf TH; Beier F
    Int J Mol Sci; 2020 Sep; 21(19):. PubMed ID: 33003434
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TERT and TERC mutations detected in cryptic dyskeratosis congenita suppress telomerase activity.
    Terada K; Miyake K; Yamaguchi H; Miyake N; Yamanaka K; Kojima S; Ito E; Inokuchi K; Okada T
    Int J Lab Hematol; 2020 Jun; 42(3):316-321. PubMed ID: 32150348
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Proliferative defects in dyskeratosis congenita skin keratinocytes are corrected by expression of the telomerase reverse transcriptase, TERT, or by activation of endogenous telomerase through expression of papillomavirus E6/E7 or the telomerase RNA component, TERC.
    Gourronc FA; Robertson mM; Herrig AK; Lansdorp PM; Goldman FD; Klingelhutz AJ
    Exp Dermatol; 2010 Mar; 19(3):279-88. PubMed ID: 19558498
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutations of telomerase complex genes linked to bone marrow failures.
    Yamaguchi H
    J Nippon Med Sch; 2007 Jun; 74(3):202-9. PubMed ID: 17625368
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts.
    Westin ER; Chavez E; Lee KM; Gourronc FA; Riley S; Lansdorp PM; Goldman FD; Klingelhutz AJ
    Aging Cell; 2007 Jun; 6(3):383-94. PubMed ID: 17381549
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Telomerase reverse-transcriptase homozygous mutations in autosomal recessive dyskeratosis congenita and Hoyeraal-Hreidarsson syndrome.
    Marrone A; Walne A; Tamary H; Masunari Y; Kirwan M; Beswick R; Vulliamy T; Dokal I
    Blood; 2007 Dec; 110(13):4198-205. PubMed ID: 17785587
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Accelerated hematopoietic stem cell aging in a mouse model of dyskeratosis congenita responds to antioxidant treatment.
    Gu BW; Fan JM; Bessler M; Mason PJ
    Aging Cell; 2011 Apr; 10(2):338-48. PubMed ID: 21241452
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bone marrow skeletal stem/progenitor cell defects in dyskeratosis congenita and telomere biology disorders.
    Balakumaran A; Mishra PJ; Pawelczyk E; Yoshizawa S; Sworder BJ; Cherman N; Kuznetsov SA; Bianco P; Giri N; Savage SA; Merlino G; Dumitriu B; Dunbar CE; Young NS; Alter BP; Robey PG
    Blood; 2015 Jan; 125(5):793-802. PubMed ID: 25499762
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rapamycin enhances long-term hematopoietic reconstitution of ex vivo expanded mouse hematopoietic stem cells by inhibiting senescence.
    Luo Y; Li L; Zou P; Wang J; Shao L; Zhou D; Liu L
    Transplantation; 2014 Jan; 97(1):20-9. PubMed ID: 24092377
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Telomerase reverse transcriptase haploinsufficiency and telomere length in individuals with 5p- syndrome.
    Du HY; Idol R; Robledo S; Ivanovich J; An P; Londono-Vallejo A; Wilson DB; Mason PJ; Bessler M
    Aging Cell; 2007 Oct; 6(5):689-97. PubMed ID: 17875000
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Generation of dyskeratosis congenita-like hematopoietic stem cells through the stable inhibition of DKC1.
    Carrascoso-Rubio C; Zittersteijn HA; Pintado-Berninches L; Fernández-Varas B; Lozano ML; Manguan-Garcia C; Sastre L; Bueren JA; Perona R; Guenechea G
    Stem Cell Res Ther; 2021 Jan; 12(1):92. PubMed ID: 33514435
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HuR regulates telomerase activity through TERC methylation.
    Tang H; Wang H; Cheng X; Fan X; Yang F; Zhang M; Chen Y; Tian Y; Liu C; Shao D; Jiang B; Dou Y; Cong Y; Xing J; Zhang X; Yi X; Songyang Z; Ma W; Zhao Y; Wang X; Ma J; Gorospe M; Ju Z; Wang W
    Nat Commun; 2018 Jun; 9(1):2213. PubMed ID: 29880812
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of primitive hematopoietic cells from patients with dyskeratosis congenita.
    Goldman FD; Aubert G; Klingelhutz AJ; Hills M; Cooper SR; Hamilton WS; Schlueter AJ; Lambie K; Eaves CJ; Lansdorp PM
    Blood; 2008 May; 111(9):4523-31. PubMed ID: 18310499
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genetic heterogeneity in autosomal recessive dyskeratosis congenita with one subtype due to mutations in the telomerase-associated protein NOP10.
    Walne AJ; Vulliamy T; Marrone A; Beswick R; Kirwan M; Masunari Y; Al-Qurashi FH; Aljurf M; Dokal I
    Hum Mol Genet; 2007 Jul; 16(13):1619-29. PubMed ID: 17507419
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification and functional characterization of 2 variant alleles of the telomerase RNA template gene (TERC) in a patient with dyskeratosis congenita.
    Ly H; Schertzer M; Jastaniah W; Davis J; Yong SL; Ouyang Q; Blackburn EH; Parslow TG; Lansdorp PM
    Blood; 2005 Aug; 106(4):1246-52. PubMed ID: 15886322
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure.
    Vulliamy TJ; Walne A; Baskaradas A; Mason PJ; Marrone A; Dokal I
    Blood Cells Mol Dis; 2005; 34(3):257-63. PubMed ID: 15885610
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Robust DNA Damage Response and Elevated Reactive Oxygen Species in TINF2-Mutated Dyskeratosis Congenita Cells.
    Pereboeva L; Hubbard M; Goldman FD; Westin ER
    PLoS One; 2016; 11(2):e0148793. PubMed ID: 26859482
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dyskeratosis congenita: telomerase, telomeres and anticipation.
    Marrone A; Walne A; Dokal I
    Curr Opin Genet Dev; 2005 Jun; 15(3):249-57. PubMed ID: 15917199
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of the mammalian target of rapamycin pathway in lentiviral vector transduction of hematopoietic stem cells.
    Wang CX; Torbett BE
    Curr Opin Hematol; 2015 Jul; 22(4):302-8. PubMed ID: 26049750
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.