These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

572 related articles for article (PubMed ID: 26551511)

  • 1. Small Molecule Active Site Directed Tools for Studying Human Caspases.
    Poreba M; Szalek A; Kasperkiewicz P; Rut W; Salvesen GS; Drag M
    Chem Rev; 2015 Nov; 115(22):12546-629. PubMed ID: 26551511
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Variation of the aryl substituent on the piperazine ring within the 4-(piperazin-1-yl)-2,6-di(pyrrolidin-1-yl)pyrimidine scaffold unveils potent, non-competitive inhibitors of the inflammatory caspases.
    Kent CR; Bryja M; Gustafson HA; Kawarski MY; Lenti G; Pierce EN; Knopp RC; Ceja V; Pati B; Walters DE; Karver CE
    Bioorg Med Chem Lett; 2016 Nov; 26(22):5476-5480. PubMed ID: 27777011
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modulating caspase activity: beyond the active site.
    Murray J; Renslo AR
    Curr Opin Struct Biol; 2013 Dec; 23(6):812-9. PubMed ID: 24215810
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Selective inhibition of initiator versus executioner caspases using small peptides containing unnatural amino acids.
    Vickers CJ; González-Páez GE; Litwin KM; Umotoy JC; Coutsias EA; Wolan DW
    ACS Chem Biol; 2014 Oct; 9(10):2194-8. PubMed ID: 25079698
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cytoprotective effect of selective small-molecule caspase inhibitors against staurosporine-induced apoptosis.
    Wu J; Wang Y; Liang S; Ma H
    Drug Des Devel Ther; 2014; 8():583-600. PubMed ID: 24920883
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The potential for caspases in drug discovery.
    MacKenzie SH; Schipper JL; Clark AC
    Curr Opin Drug Discov Devel; 2010 Sep; 13(5):568-76. PubMed ID: 20812148
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Non-steroidal Anti-inflammatory Drugs Are Caspase Inhibitors.
    Smith CE; Soti S; Jones TA; Nakagawa A; Xue D; Yin H
    Cell Chem Biol; 2017 Mar; 24(3):281-292. PubMed ID: 28238723
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of Allosteric Inhibitors against Active Caspase-6.
    Tubeleviciute-Aydin A; Beautrait A; Lynham J; Sharma G; Gorelik A; Deny LJ; Soya N; Lukacs GL; Nagar B; Marinier A; LeBlanc AC
    Sci Rep; 2019 Apr; 9(1):5504. PubMed ID: 30940883
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In Vitro Use of Peptide Based Substrates and Inhibitors of Apoptotic Caspases.
    McStay GP
    Methods Mol Biol; 2016; 1419():57-67. PubMed ID: 27108431
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selective detection and inhibition of active caspase-3 in cells with optimized peptides.
    Vickers CJ; González-Páez GE; Wolan DW
    J Am Chem Soc; 2013 Aug; 135(34):12869-76. PubMed ID: 23915420
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lazaroids U83836E and U74389G are potent, time-dependent inhibitors of caspase-1.
    Kawarski M; Hagerman TK; Karver CE
    Chem Biol Drug Des; 2015 Nov; 86(5):1049-54. PubMed ID: 25871734
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Exploring the prime site in caspases as a novel chemical strategy for understanding the mechanisms of cell death: a proof of concept study on necroptosis in cancer cells.
    Groborz K; Gonzalez Ramirez ML; Snipas SJ; Salvesen GS; Drąg M; Poręba M
    Cell Death Differ; 2020 Feb; 27(2):451-465. PubMed ID: 31209360
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibiting caspase-6 activation and catalytic activity for neurodegenerative diseases.
    Flygare JA; Arkin MR
    Curr Top Med Chem; 2014; 14(3):319-25. PubMed ID: 24283214
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pharmacological caspase inhibitors: research towards therapeutic perspectives.
    Kudelova J; Fleischmannova J; Adamova E; Matalova E
    J Physiol Pharmacol; 2015 Aug; 66(4):473-82. PubMed ID: 26348072
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A class of allosteric caspase inhibitors identified by high-throughput screening.
    Feldman T; Kabaleeswaran V; Jang SB; Antczak C; Djaballah H; Wu H; Jiang X
    Mol Cell; 2012 Aug; 47(4):585-95. PubMed ID: 22795132
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Conformational restrictions in the active site of unliganded human caspase-3.
    Ni CZ; Li C; Wu JC; Spada AP; Ely KR
    J Mol Recognit; 2003; 16(3):121-4. PubMed ID: 12833566
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Caspase substrates and inhibitors.
    Poreba M; Strózyk A; Salvesen GS; Drag M
    Cold Spring Harb Perspect Biol; 2013 Aug; 5(8):a008680. PubMed ID: 23788633
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Application of the Movable Type Free Energy Method to the Caspase-Inhibitor BindingAffinity Study.
    Xue S; Liu H; Zheng Z
    Int J Mol Sci; 2019 Sep; 20(19):. PubMed ID: 31569580
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Controlled Inhibition of Apoptosis by Photoactivatable Caspase Inhibitors.
    Chakrabarty S; Verhelst SHL
    Cell Chem Biol; 2020 Nov; 27(11):1434-1440.e10. PubMed ID: 32814013
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Caspase Allostery and Conformational Selection.
    Clark AC
    Chem Rev; 2016 Jun; 116(11):6666-706. PubMed ID: 26750439
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.