347 related articles for article (PubMed ID: 26551712)
1. Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention.
Harder B; Jiang T; Wu T; Tao S; Rojo de la Vega M; Tian W; Chapman E; Zhang DD
Biochem Soc Trans; 2015 Aug; 43(4):680-6. PubMed ID: 26551712
[TBL] [Abstract][Full Text] [Related]
2. Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases.
Villeneuve NF; Lau A; Zhang DD
Antioxid Redox Signal; 2010 Dec; 13(11):1699-712. PubMed ID: 20486766
[TBL] [Abstract][Full Text] [Related]
3. Frequent concerted genetic mechanisms disrupt multiple components of the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in thyroid cancer.
Martinez VD; Vucic EA; Pikor LA; Thu KL; Hubaux R; Lam WL
Mol Cancer; 2013 Oct; 12(1):124. PubMed ID: 24138990
[TBL] [Abstract][Full Text] [Related]
4. The Keap1-Nrf2 system as an in vivo sensor for electrophiles.
Uruno A; Motohashi H
Nitric Oxide; 2011 Aug; 25(2):153-60. PubMed ID: 21385624
[TBL] [Abstract][Full Text] [Related]
5. The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic.
O'Connell MA; Hayes JD
Biochem Soc Trans; 2015 Aug; 43(4):687-9. PubMed ID: 26551713
[TBL] [Abstract][Full Text] [Related]
6. USP15 negatively regulates Nrf2 through deubiquitination of Keap1.
Villeneuve NF; Tian W; Wu T; Sun Z; Lau A; Chapman E; Fang D; Zhang DD
Mol Cell; 2013 Jul; 51(1):68-79. PubMed ID: 23727018
[TBL] [Abstract][Full Text] [Related]
7. p97 Negatively Regulates NRF2 by Extracting Ubiquitylated NRF2 from the KEAP1-CUL3 E3 Complex.
Tao S; Liu P; Luo G; Rojo de la Vega M; Chen H; Wu T; Tillotson J; Chapman E; Zhang DD
Mol Cell Biol; 2017 Apr; 37(8):. PubMed ID: 28115426
[TBL] [Abstract][Full Text] [Related]
8. Dual regulation of transcription factor Nrf2 by Keap1 and by the combined actions of β-TrCP and GSK-3.
Hayes JD; Chowdhry S; Dinkova-Kostova AT; Sutherland C
Biochem Soc Trans; 2015 Aug; 43(4):611-20. PubMed ID: 26551701
[TBL] [Abstract][Full Text] [Related]
9. Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease.
Tebay LE; Robertson H; Durant ST; Vitale SR; Penning TM; Dinkova-Kostova AT; Hayes JD
Free Radic Biol Med; 2015 Nov; 88(Pt B):108-146. PubMed ID: 26122708
[TBL] [Abstract][Full Text] [Related]
10. Canonical and non-canonical mechanisms of Nrf2 activation.
Silva-Islas CA; Maldonado PD
Pharmacol Res; 2018 Aug; 134():92-99. PubMed ID: 29913224
[TBL] [Abstract][Full Text] [Related]
11. Unique pattern of component gene disruption in the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in serous ovarian cancer.
Martinez VD; Vucic EA; Thu KL; Pikor LA; Hubaux R; Lam WL
Biomed Res Int; 2014; 2014():159459. PubMed ID: 25114896
[TBL] [Abstract][Full Text] [Related]
12. Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution.
Taguchi K; Motohashi H; Yamamoto M
Genes Cells; 2011 Feb; 16(2):123-40. PubMed ID: 21251164
[TBL] [Abstract][Full Text] [Related]
13. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2.
Sun Z; Zhang S; Chan JY; Zhang DD
Mol Cell Biol; 2007 Sep; 27(18):6334-49. PubMed ID: 17636022
[TBL] [Abstract][Full Text] [Related]
14. SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner.
Rada P; Rojo AI; Chowdhry S; McMahon M; Hayes JD; Cuadrado A
Mol Cell Biol; 2011 Mar; 31(6):1121-33. PubMed ID: 21245377
[TBL] [Abstract][Full Text] [Related]
15. Sp1 is a substrate of Keap1 and regulates the activity of CRL4A
Siswanto FM; Oguro A; Imaoka S
J Biol Chem; 2021; 296():100704. PubMed ID: 33895141
[TBL] [Abstract][Full Text] [Related]
16. Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents.
Giudice A; Arra C; Turco MC
Methods Mol Biol; 2010; 647():37-74. PubMed ID: 20694660
[TBL] [Abstract][Full Text] [Related]
17. Keap1 degradation by autophagy for the maintenance of redox homeostasis.
Taguchi K; Fujikawa N; Komatsu M; Ishii T; Unno M; Akaike T; Motohashi H; Yamamoto M
Proc Natl Acad Sci U S A; 2012 Aug; 109(34):13561-6. PubMed ID: 22872865
[TBL] [Abstract][Full Text] [Related]
18. A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62.
Lau A; Wang XJ; Zhao F; Villeneuve NF; Wu T; Jiang T; Sun Z; White E; Zhang DD
Mol Cell Biol; 2010 Jul; 30(13):3275-85. PubMed ID: 20421418
[TBL] [Abstract][Full Text] [Related]
19. Disruption of KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex components by multiple genetic mechanisms: Association with poor prognosis in head and neck cancer.
Martinez VD; Vucic EA; Thu KL; Pikor LA; Lam S; Lam WL
Head Neck; 2015 May; 37(5):727-34. PubMed ID: 24596130
[TBL] [Abstract][Full Text] [Related]
20. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.
Zhang DD; Lo SC; Cross JV; Templeton DJ; Hannink M
Mol Cell Biol; 2004 Dec; 24(24):10941-53. PubMed ID: 15572695
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
