BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

269 related articles for article (PubMed ID: 26552797)

  • 1. Overproduction of lactimidomycin by cross-overexpression of genes encoding Streptomyces antibiotic regulatory proteins.
    Zhang B; Yang D; Yan Y; Pan G; Xiang W; Shen B
    Appl Microbiol Biotechnol; 2016 Mar; 100(5):2267-77. PubMed ID: 26552797
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparative characterization of the lactimidomycin and iso-migrastatin biosynthetic machineries revealing unusual features for acyltransferase-less type I polyketide synthases and providing an opportunity to engineer new analogues.
    Seo JW; Ma M; Kwong T; Ju J; Lim SK; Jiang H; Lohman JR; Yang C; Cleveland J; Zazopoulos E; Farnet CM; Shen B
    Biochemistry; 2014 Dec; 53(49):7854-65. PubMed ID: 25405956
    [TBL] [Abstract][Full Text] [Related]  

  • 3. iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.
    Lim SK; Ju J; Zazopoulos E; Jiang H; Seo JW; Chen Y; Feng Z; Rajski SR; Farnet CM; Shen B
    J Biol Chem; 2009 Oct; 284(43):29746-56. PubMed ID: 19726666
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Engineered production of iso-migrastatin in heterologous Streptomyces hosts.
    Feng Z; Wang L; Rajski SR; Xu Z; Coeffet-LeGal MF; Shen B
    Bioorg Med Chem; 2009 Mar; 17(6):2147-53. PubMed ID: 19010685
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New lactimidomycin congeners shed insight into lactimidomycin biosynthesis in Streptomyces amphibiosporus.
    Ju J; Seo JW; Her Y; Lim SK; Shen B
    Org Lett; 2007 Dec; 9(25):5183-6. PubMed ID: 17997563
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Titer improvement of iso-migrastatin in selected heterologous Streptomyces hosts and related analysis of mRNA expression by quantitative RT-PCR.
    Yang D; Zhu X; Wu X; Feng Z; Huang L; Shen B; Xu Z
    Appl Microbiol Biotechnol; 2011 Mar; 89(6):1709-19. PubMed ID: 21132287
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Iso-migrastatin congeners from Streptomyces platensis and generation of a glutarimide polyketide library featuring the dorrigocin, lactimidomycin, migrastatin, and NK30424 scaffolds.
    Ju J; Lim SK; Jiang H; Seo JW; Shen B
    J Am Chem Soc; 2005 Aug; 127(34):11930-1. PubMed ID: 16117518
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Involvement of AlpV, a new member of the Streptomyces antibiotic regulatory protein family, in regulation of the duplicated type II polyketide synthase alp gene cluster in Streptomyces ambofaciens.
    Aigle B; Pang X; Decaris B; Leblond P
    J Bacteriol; 2005 Apr; 187(7):2491-500. PubMed ID: 15774892
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Promoter Engineering Reveals the Importance of Heptameric Direct Repeats for DNA Binding by Streptomyces Antibiotic Regulatory Protein-Large ATP-Binding Regulator of the LuxR Family (SARP-LAL) Regulators in Streptomyces natalensis.
    Barreales EG; Vicente CM; de Pedro A; Santos-Aberturas J; Aparicio JF
    Appl Environ Microbiol; 2018 May; 84(10):. PubMed ID: 29500267
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biosynthesis of 9-methylstreptimidone involves a new decarboxylative step for polyketide terminal diene formation.
    Wang B; Song Y; Luo M; Chen Q; Ma J; Huang H; Ju J
    Org Lett; 2013 Mar; 15(6):1278-81. PubMed ID: 23438151
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Heterologous expression of pikromycin biosynthetic gene cluster using Streptomyces artificial chromosome system.
    Pyeon HR; Nah HJ; Kang SH; Choi SS; Kim ES
    Microb Cell Fact; 2017 May; 16(1):96. PubMed ID: 28569150
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of LnmO as a pathway-specific Crp/Fnr-type positive regulator for leinamycin biosynthesis in Streptomyces atroolivaceus and its application for titer improvement.
    Huang Y; Yang D; Pan G; Tang GL; Shen B
    Appl Microbiol Biotechnol; 2016 Dec; 100(24):10555-10562. PubMed ID: 27704182
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential contributions of two SARP family regulatory genes to indigoidine biosynthesis in Streptomyces lavendulae FRI-5.
    Kurniawan YN; Kitani S; Maeda A; Nihira T
    Appl Microbiol Biotechnol; 2014 Dec; 98(23):9713-21. PubMed ID: 25125041
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Post-polyketide synthase steps in iso-migrastatin biosynthesis, featuring tailoring enzymes with broad substrate specificity.
    Ma M; Kwong T; Lim SK; Ju J; Lohman JR; Shen B
    J Am Chem Soc; 2013 Feb; 135(7):2489-92. PubMed ID: 23394593
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of the biosynthetic gene cluster and regulatory cascade for the synergistic antibacterial antibiotics griseoviridin and viridogrisein in Streptomyces griseoviridis.
    Xie Y; Wang B; Liu J; Zhou J; Ma J; Huang H; Ju J
    Chembiochem; 2012 Dec; 13(18):2745-57. PubMed ID: 23161816
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of three regulatory genes involved in enduracidin biosynthesis and improvement of enduracidin production in Streptomyces fungicidicus.
    Chen YW; Liu XC; Lv FX; Li P
    J Appl Microbiol; 2019 Dec; 127(6):1698-1705. PubMed ID: 31424146
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Hierarchical Network of Four Regulatory Genes Controlling Production of the Polyene Antibiotic Candicidin in
    Zhu Y; Xu W; Zhang J; Zhang P; Zhao Z; Sheng D; Ma W; Zhang YZ; Bai L; Pang X
    Appl Environ Microbiol; 2020 Apr; 86(9):. PubMed ID: 32086301
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hierarchical control on polyene macrolide biosynthesis: PimR modulates pimaricin production via the PAS-LuxR transcriptional activator PimM.
    Santos-Aberturas J; Vicente CM; Payero TD; Martín-Sánchez L; Cañibano C; Martín JF; Aparicio JF
    PLoS One; 2012; 7(6):e38536. PubMed ID: 22693644
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lactimidomycin, iso-migrastatin and related glutarimide-containing 12-membered macrolides are extremely potent inhibitors of cell migration.
    Ju J; Rajski SR; Lim SK; Seo JW; Peters NR; Hoffmann FM; Shen B
    J Am Chem Soc; 2009 Feb; 131(4):1370-1. PubMed ID: 19132897
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Iso-migrastatin Titer Improvement in the Engineered Streptomyces lividans SB11002 Strain by Optimization of Fermentation Conditions.
    Wu X; Yang D; Zhu X; Feng Z; Lv Z; Zhang Y; Shen B; Xu Z
    Biotechnol Bioprocess Eng; 2010 Aug; 15(4):664-669. PubMed ID: 21625393
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.