BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 26553872)

  • 1. Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION.
    Realini N; Palese F; Pizzirani D; Pontis S; Basit A; Bach A; Ganesan A; Piomelli D
    J Biol Chem; 2016 Jan; 291(5):2422-34. PubMed ID: 26553872
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural Basis for Ceramide Recognition and Hydrolysis by Human Neutral Ceramidase.
    Airola MV; Allen WJ; Pulkoski-Gross MJ; Obeid LM; Rizzo RC; Hannun YA
    Structure; 2015 Aug; 23(8):1482-1491. PubMed ID: 26190575
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Manipulation of the Sphingolipid Rheostat Influences the Mediator of Flow-Induced Dilation in the Human Microvasculature.
    Schulz ME; Katunaric B; Hockenberry JC; Gutterman DD; Freed JK
    J Am Heart Assoc; 2019 Sep; 8(17):e013153. PubMed ID: 31462128
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A simple, highly sensitive, and facile method to quantify ceramide at the plasma membrane.
    Greene M; Hernandez-Corbacho MJ; Ostermeyer-Fay AG; Hannun YA; Canals D
    J Lipid Res; 2023 Feb; 64(2):100322. PubMed ID: 36549592
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia.
    Ung J; Tan SF; Fox TE; Shaw JJP; Taori M; Horton BJ; Golla U; Sharma A; Szulc ZM; Wang HG; Chalfant CE; Cabot MC; Claxton DF; Loughran TP; Feith DJ
    Cancers (Basel); 2023 Dec; 15(24):. PubMed ID: 38136410
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia.
    Ung J; Tan SF; Fox TE; Shaw JJ; Taori M; Horton BJ; Golla U; Sharma A; Szulc ZM; Wang HG; Chalfant CE; Cabot MC; Claxton DF; Loughran TP; Feith DJ
    bioRxiv; 2023 Oct; ():. PubMed ID: 37961314
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Benzoxazolone Carboxamides as Potent Acid Ceramidase Inhibitors: Synthesis and Structure-Activity Relationship (SAR) Studies.
    Bach A; Pizzirani D; Realini N; Vozella V; Russo D; Penna I; Melzig L; Scarpelli R; Piomelli D
    J Med Chem; 2015 Dec; 58(23):9258-72. PubMed ID: 26560855
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Acid ceramidase and the treatment of ceramide diseases: The expanding role of enzyme replacement therapy.
    Schuchman EH
    Biochim Biophys Acta; 2016 Sep; 1862(9):1459-71. PubMed ID: 27155573
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting acid ceramidase sensitises head and neck cancer to cisplatin.
    Roh JL; Park JY; Kim EH; Jang HJ
    Eur J Cancer; 2016 Jan; 52():163-72. PubMed ID: 26687835
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Complete Acid Ceramidase ablation prevents cancer-initiating cell formation in melanoma cells.
    Lai M; Realini N; La Ferla M; Passalacqua I; Matteoli G; Ganesan A; Pistello M; Mazzanti CM; Piomelli D
    Sci Rep; 2017 Aug; 7(1):7411. PubMed ID: 28785021
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of New Acid Ceramidase-Targeted Acyclic 5-Alkynyl and 5-Heteroaryl Uracil Nucleosides.
    Meščić A; Harej A; Klobučar M; Glavač D; Cetina M; Pavelić SK; Raić-Malić S
    ACS Med Chem Lett; 2015 Nov; 6(11):1150-5. PubMed ID: 26617970
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bifunctional Sphingosine for Cell-Based Analysis of Protein-Sphingolipid Interactions.
    Haberkant P; Stein F; Höglinger D; Gerl MJ; Brügger B; Van Veldhoven PP; Krijgsveld J; Gavin AC; Schultz C
    ACS Chem Biol; 2016 Jan; 11(1):222-30. PubMed ID: 26555438
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Acid ceramidase is upregulated in AML and represents a novel therapeutic target.
    Tan SF; Liu X; Fox TE; Barth BM; Sharma A; Turner SD; Awwad A; Dewey A; Doi K; Spitzer B; Shah MV; Morad SA; Desai D; Amin S; Zhu J; Liao J; Yun J; Kester M; Claxton DF; Wang HG; Cabot MC; Schuchman EH; Levine RL; Feith DJ; Loughran TP
    Oncotarget; 2016 Dec; 7(50):83208-83222. PubMed ID: 27825124
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ceramidases, roles in sphingolipid metabolism and in health and disease.
    Coant N; Sakamoto W; Mao C; Hannun YA
    Adv Biol Regul; 2017 Jan; 63():122-131. PubMed ID: 27771292
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of Ceramide from Glycosphingolipids and Its Metabolites in Immunological and Inflammatory Responses in Humans.
    Iwabuchi K; Nakayama H; Oizumi A; Suga Y; Ogawa H; Takamori K
    Mediators Inflamm; 2015; 2015():120748. PubMed ID: 26609196
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The outcomes of Polish patients with advanced BRAF-positive melanoma treated with vemurafenib in a safety clinical trial.
    Rutkowski P; Kozak K; Mackiewicz J; Krzemieniecki K; Nawrocki S; Wasilewska-Teśluk E; Kwinta Ł; Wysocki P; Koseła-Paterczyk H; Świtaj T
    Contemp Oncol (Pozn); 2015; 19(4):280-3. PubMed ID: 26557775
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease.
    Lang J; Bohn P; Bhat H; Jastrow H; Walkenfort B; Cansiz F; Fink J; Bauer M; Olszewski D; Ramos-Nascimento A; Duhan V; Friedrich SK; Becker KA; Krawczyk A; Edwards MJ; Burchert A; Huber M; Friebus-Kardash J; Göthert JR; Hardt C; Probst HC; Schumacher F; Köhrer K; Kleuser B; Babiychuk EB; Sodeik B; Seibel J; Greber UF; Lang PA; Gulbins E; Lang KS
    Nat Commun; 2020 Mar; 11(1):1338. PubMed ID: 32165633
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target.
    Ellermann M; Eheim A; Rahm F; Viklund J; Guenther J; Andersson M; Ericsson U; Forsblom R; Ginman T; Lindström J; Silvander C; Trésaugues L; Giese A; Bunse S; Neuhaus R; Weiske J; Quanz M; Glasauer A; Nowak-Reppel K; Bader B; Irlbacher H; Meyer H; Queisser N; Bauser M; Haegebarth A; Gorjánácz M
    ACS Chem Biol; 2017 Aug; 12(8):1986-1992. PubMed ID: 28679043
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A fluorogenic substrate for the detection of lipid amidases in intact cells.
    Casasampere M; Ung J; Iñáñez A; Dufau C; Tsuboi K; Casas J; Tan SF; Feith DJ; Andrieu-Abadie N; Segui B; Loughran TP; Abad JL; Fabrias G
    J Lipid Res; 2024 Mar; 65(3):100520. PubMed ID: 38369184
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Natural Products and Small Molecules Targeting Cellular Ceramide Metabolism to Enhance Apoptosis in Cancer Cells.
    Afrin F; Mateen S; Oman J; Lai JCK; Barrott JJ; Pashikanti S
    Cancers (Basel); 2023 Sep; 15(18):. PubMed ID: 37760612
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.