BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 26561568)

  • 1. ADAM17 controls IL-6 signaling by cleavage of the murine IL-6Rα from the cell surface of leukocytes during inflammatory responses.
    Yan I; Schwarz J; Lücke K; Schumacher N; Schumacher V; Schmidt S; Rabe B; Saftig P; Donners M; Rose-John S; Mittrücker HW; Chalaris A
    J Leukoc Biol; 2016 May; 99(5):749-60. PubMed ID: 26561568
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cleavage Site Localization Differentially Controls Interleukin-6 Receptor Proteolysis by ADAM10 and ADAM17.
    Riethmueller S; Ehlers JC; Lokau J; Düsterhöft S; Knittler K; Dombrowsky G; Grötzinger J; Rabe B; Rose-John S; Garbers C
    Sci Rep; 2016 May; 6():25550. PubMed ID: 27151651
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IL-6 controls the innate immune response against Listeria monocytogenes via classical IL-6 signaling.
    Hoge J; Yan I; Jänner N; Schumacher V; Chalaris A; Steinmetz OM; Engel DR; Scheller J; Rose-John S; Mittrücker HW
    J Immunol; 2013 Jan; 190(2):703-11. PubMed ID: 23241882
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of ADAM17 in the T-cell response against bacterial pathogens.
    Link MA; Lücke K; Schmid J; Schumacher V; Eden T; Rose-John S; Mittrücker HW
    PLoS One; 2017; 12(9):e0184320. PubMed ID: 28877252
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling.
    Arnold P; Boll I; Rothaug M; Schumacher N; Schmidt F; Wichert R; Schneppenheim J; Lokau J; Pickhinke U; Koudelka T; Tholey A; Rabe B; Scheller J; Lucius R; Garbers C; Rose-John S; Becker-Pauly C
    Sci Rep; 2017 Mar; 7():44053. PubMed ID: 28276471
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Minimal interleukin 6 (IL-6) receptor stalk composition for IL-6 receptor shedding and IL-6 classic signaling.
    Baran P; Nitz R; Grötzinger J; Scheller J; Garbers C
    J Biol Chem; 2013 May; 288(21):14756-68. PubMed ID: 23564454
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Circulating Soluble IL-6R but Not ADAM17 Activation Drives Mononuclear Cell Migration in Tissue Inflammation.
    Schumacher N; Schmidt S; Schwarz J; Dohr D; Lokau J; Scheller J; Garbers C; Chalaris A; Rose-John S; Rabe B
    J Immunol; 2016 Nov; 197(9):3705-3715. PubMed ID: 27698010
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human and Murine Interleukin 23 Receptors Are Novel Substrates for A Disintegrin and Metalloproteases ADAM10 and ADAM17.
    Franke M; Schröder J; Monhasery N; Ackfeld T; Hummel TM; Rabe B; Garbers C; Becker-Pauly C; Floss DM; Scheller J
    J Biol Chem; 2016 May; 291(20):10551-61. PubMed ID: 26961870
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Control of Listeria monocytogenes infection requires classical IL-6 signaling in myeloid cells.
    Lücke K; Yan I; Krohn S; Volmari A; Klinge S; Schmid J; Schumacher V; Steinmetz OM; Rose-John S; Mittrücker HW
    PLoS One; 2018; 13(8):e0203395. PubMed ID: 30169526
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The interleukin-6 receptor Asp358Ala single nucleotide polymorphism rs2228145 confers increased proteolytic conversion rates by ADAM proteases.
    Garbers C; Monhasery N; Aparicio-Siegmund S; Lokau J; Baran P; Nowell MA; Jones SA; Rose-John S; Scheller J
    Biochim Biophys Acta; 2014 Sep; 1842(9):1485-94. PubMed ID: 24878322
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Species specificity of ADAM10 and ADAM17 proteins in interleukin-6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding.
    Garbers C; Jänner N; Chalaris A; Moss ML; Floss DM; Meyer D; Koch-Nolte F; Rose-John S; Scheller J
    J Biol Chem; 2011 Apr; 286(17):14804-11. PubMed ID: 21454673
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The metalloprotease ADAM10 generates soluble interleukin-2 receptor alpha (sCD25) in vivo.
    Kirschke S; Ogunsulire I; Selvakumar B; Schumacher N; Sezin T; Rose-John S; Scheffold A; Garbers C; Lokau J
    J Biol Chem; 2022 Jun; 298(6):101910. PubMed ID: 35398356
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Secreted Frizzled-related protein 3 (sFRP3)-mediated suppression of interleukin-6 receptor release by A disintegrin and metalloprotease 17 (ADAM17) is abrogated in the osteoarthritis-associated rare double variant of sFRP3.
    Oldefest M; Düsterhöft S; Desel C; Thysen S; Fink C; Rabe B; Lories R; Grötzinger J; Lorenzen I
    Biochem J; 2015 Jun; 468(3):507-18. PubMed ID: 25846075
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Different Soluble Forms of the Interleukin-6 Family Signal Transducer gp130 Fine-tune the Blockade of Interleukin-6 Trans-signaling.
    Wolf J; Waetzig GH; Chalaris A; Reinheimer TM; Wege H; Rose-John S; Garbers C
    J Biol Chem; 2016 Jul; 291(31):16186-96. PubMed ID: 27226573
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Gut-Brain Axis in Autism Spectrum Disorder: A Focus on the Metalloproteases ADAM10 and ADAM17.
    Zheng Y; Verhoeff TA; Perez Pardo P; Garssen J; Kraneveld AD
    Int J Mol Sci; 2020 Dec; 22(1):. PubMed ID: 33374371
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The membrane-proximal domain of A Disintegrin and Metalloprotease 17 (ADAM17) is responsible for recognition of the interleukin-6 receptor and interleukin-1 receptor II.
    Lorenzen I; Lokau J; Düsterhöft S; Trad A; Garbers C; Scheller J; Rose-John S; Grötzinger J
    FEBS Lett; 2012 Apr; 586(8):1093-100. PubMed ID: 22575642
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Meprin β induces activities of A disintegrin and metalloproteinases 9, 10, and 17 by specific prodomain cleavage.
    Wichert R; Scharfenberg F; Colmorgen C; Koudelka T; Schwarz J; Wetzel S; Potempa B; Potempa J; Bartsch JW; Sagi I; Tholey A; Saftig P; Rose-John S; Becker-Pauly C
    FASEB J; 2019 Nov; 33(11):11925-11940. PubMed ID: 31381863
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ADAM17-mediated shedding of the IL6R induces cleavage of the membrane stub by gamma-secretase.
    Chalaris A; Gewiese J; Paliga K; Fleig L; Schneede A; Krieger K; Rose-John S; Scheller J
    Biochim Biophys Acta; 2010 Feb; 1803(2):234-45. PubMed ID: 20026129
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Estrogen downregulates gp130 expression in HUVECs by regulating ADAM10 and ADAM17 via the estrogen receptor.
    Zhou M; Dai W; Cui Y; Li Y
    Biochem Biophys Res Commun; 2020 Mar; 523(3):753-758. PubMed ID: 31952790
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of Toll-like Receptor 2 (TLR2) induces Interleukin-6 trans-signaling.
    Flynn CM; Garbers Y; Lokau J; Wesch D; Schulte DM; Laudes M; Lieb W; Aparicio-Siegmund S; Garbers C
    Sci Rep; 2019 May; 9(1):7306. PubMed ID: 31086276
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.