439 related articles for article (PubMed ID: 26562265)
1. Binding Selectivity of Abaloparatide for PTH-Type-1-Receptor Conformations and Effects on Downstream Signaling.
Hattersley G; Dean T; Corbin BA; Bahar H; Gardella TJ
Endocrinology; 2016 Jan; 157(1):141-9. PubMed ID: 26562265
[TBL] [Abstract][Full Text] [Related]
2. Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation.
Okazaki M; Ferrandon S; Vilardaga JP; Bouxsein ML; Potts JT; Gardella TJ
Proc Natl Acad Sci U S A; 2008 Oct; 105(43):16525-30. PubMed ID: 18946036
[TBL] [Abstract][Full Text] [Related]
3. Evaluating the signal transduction mechanism of the parathyroid hormone 1 receptor. Effect of receptor-G-protein interaction on the ligand binding mechanism and receptor conformation.
Hoare SR; Gardella TJ; Usdin TB
J Biol Chem; 2001 Mar; 276(11):7741-53. PubMed ID: 11108715
[TBL] [Abstract][Full Text] [Related]
4. Abaloparatide, the second generation osteoanabolic drug: Molecular mechanisms underlying its advantages over the first-in-class teriparatide.
Bhattacharyya S; Pal S; Chattopadhyay N
Biochem Pharmacol; 2019 Aug; 166():185-191. PubMed ID: 31136739
[TBL] [Abstract][Full Text] [Related]
5. Parathyroid hormone (PTH) and PTH-related peptide domains contributing to activation of different PTH receptor-mediated signaling pathways.
Cupp ME; Nayak SK; Adem AS; Thomsen WJ
J Pharmacol Exp Ther; 2013 Jun; 345(3):404-18. PubMed ID: 23516330
[TBL] [Abstract][Full Text] [Related]
6. Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor.
Dean T; Vilardaga JP; Potts JT; Gardella TJ
Mol Endocrinol; 2008 Jan; 22(1):156-66. PubMed ID: 17872377
[TBL] [Abstract][Full Text] [Related]
7. Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides.
Pioszak AA; Parker NR; Gardella TJ; Xu HE
J Biol Chem; 2009 Oct; 284(41):28382-28391. PubMed ID: 19674967
[TBL] [Abstract][Full Text] [Related]
8. Mechanisms of ligand binding to the parathyroid hormone (PTH)/PTH-related protein receptor: selectivity of a modified PTH(1-15) radioligand for GalphaS-coupled receptor conformations.
Dean T; Linglart A; Mahon MJ; Bastepe M; Jüppner H; Potts JT; Gardella TJ
Mol Endocrinol; 2006 Apr; 20(4):931-43. PubMed ID: 16339275
[TBL] [Abstract][Full Text] [Related]
9. Biasing the parathyroid hormone receptor: relating in vitro ligand efficacy to in vivo biological activity.
Appleton KM; Lee MH; Alele C; Alele C; Luttrell DK; Peterson YK; Morinelli TA; Luttrell LM
Methods Enzymol; 2013; 522():229-62. PubMed ID: 23374189
[TBL] [Abstract][Full Text] [Related]
10. Current perspectives on parathyroid hormone (PTH) and PTH-related protein (PTHrP) as bone anabolic therapies.
Esbrit P; Alcaraz MJ
Biochem Pharmacol; 2013 May; 85(10):1417-23. PubMed ID: 23500550
[TBL] [Abstract][Full Text] [Related]
11. Histidine at position 5 is the specificity "switch" between two parathyroid hormone receptor subtypes.
Behar V; Nakamoto C; Greenberg Z; Bisello A; Suva LJ; Rosenblatt M; Chorev M
Endocrinology; 1996 Oct; 137(10):4217-24. PubMed ID: 8828480
[TBL] [Abstract][Full Text] [Related]
12. Physiological and Pharmacological Roles of PTH and PTHrP in Bone Using Their Shared Receptor, PTH1R.
Martin TJ; Sims NA; Seeman E
Endocr Rev; 2021 Jul; 42(4):383-406. PubMed ID: 33564837
[TBL] [Abstract][Full Text] [Related]
13. Bone-related growth factors and zoledronic acid regulate the PTHrP/PTH.1 receptor bioregulation systems in MG-63 human osteosarcoma cells.
Tenta R; Sourla A; Lembessis P; Koutsilieris M
Anticancer Res; 2006; 26(1A):283-91. PubMed ID: 16475708
[TBL] [Abstract][Full Text] [Related]
14. Endogenous ligand recognition and structural transition of a human PTH receptor.
Kobayashi K; Kawakami K; Kusakizako T; Miyauchi H; Tomita A; Kobayashi K; Shihoya W; Yamashita K; Nishizawa T; Kato HE; Inoue A; Nureki O
Mol Cell; 2022 Sep; 82(18):3468-3483.e5. PubMed ID: 35932760
[TBL] [Abstract][Full Text] [Related]
15. The human PTH2 receptor: binding and signal transduction properties of the stably expressed recombinant receptor.
Behar V; Pines M; Nakamoto C; Greenberg Z; Bisello A; Stueckle SM; Bessalle R; Usdin TB; Chorev M; Rosenblatt M; Suva LJ
Endocrinology; 1996 Jul; 137(7):2748-57. PubMed ID: 8770894
[TBL] [Abstract][Full Text] [Related]
16. Investigational parathyroid hormone receptor analogs for the treatment of osteoporosis.
Polyzos SA; Makras P; Efstathiadou Z; Anastasilakis AD
Expert Opin Investig Drugs; 2015 Feb; 24(2):145-57. PubMed ID: 25316089
[TBL] [Abstract][Full Text] [Related]
17. Tuberoinfundibular peptide (7-39) [TIP(7-39)], a novel, selective, high-affinity antagonist for the parathyroid hormone-1 receptor with no detectable agonist activity.
Hoare SR; Usdin TB
J Pharmacol Exp Ther; 2000 Nov; 295(2):761-70. PubMed ID: 11046116
[TBL] [Abstract][Full Text] [Related]
18. The extracellular amino-terminal region of the parathyroid hormone (PTH)/PTH-related peptide receptor determines the binding affinity for carboxyl-terminal fragments of PTH-(1-34).
Jüppner H; Schipani E; Bringhurst FR; McClure I; Keutmann HT; Potts JT; Kronenberg HM; Abou-Samra AB; Segre GV; Gardella TJ
Endocrinology; 1994 Feb; 134(2):879-84. PubMed ID: 8299582
[TBL] [Abstract][Full Text] [Related]
19. International Union of Basic and Clinical Pharmacology. XCIII. The parathyroid hormone receptors--family B G protein-coupled receptors.
Gardella TJ; Vilardaga JP
Pharmacol Rev; 2015; 67(2):310-37. PubMed ID: 25713287
[TBL] [Abstract][Full Text] [Related]
20. Cyclic adenosine monophosphate/protein kinase A mediates parathyroid hormone/parathyroid hormone-related protein receptor regulation of osteoclastogenesis and expression of RANKL and osteoprotegerin mRNAs by marrow stromal cells.
Kondo H; Guo J; Bringhurst FR
J Bone Miner Res; 2002 Sep; 17(9):1667-79. PubMed ID: 12211438
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]