BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

439 related articles for article (PubMed ID: 26562265)

  • 1. Binding Selectivity of Abaloparatide for PTH-Type-1-Receptor Conformations and Effects on Downstream Signaling.
    Hattersley G; Dean T; Corbin BA; Bahar H; Gardella TJ
    Endocrinology; 2016 Jan; 157(1):141-9. PubMed ID: 26562265
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation.
    Okazaki M; Ferrandon S; Vilardaga JP; Bouxsein ML; Potts JT; Gardella TJ
    Proc Natl Acad Sci U S A; 2008 Oct; 105(43):16525-30. PubMed ID: 18946036
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evaluating the signal transduction mechanism of the parathyroid hormone 1 receptor. Effect of receptor-G-protein interaction on the ligand binding mechanism and receptor conformation.
    Hoare SR; Gardella TJ; Usdin TB
    J Biol Chem; 2001 Mar; 276(11):7741-53. PubMed ID: 11108715
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Abaloparatide, the second generation osteoanabolic drug: Molecular mechanisms underlying its advantages over the first-in-class teriparatide.
    Bhattacharyya S; Pal S; Chattopadhyay N
    Biochem Pharmacol; 2019 Aug; 166():185-191. PubMed ID: 31136739
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Parathyroid hormone (PTH) and PTH-related peptide domains contributing to activation of different PTH receptor-mediated signaling pathways.
    Cupp ME; Nayak SK; Adem AS; Thomsen WJ
    J Pharmacol Exp Ther; 2013 Jun; 345(3):404-18. PubMed ID: 23516330
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor.
    Dean T; Vilardaga JP; Potts JT; Gardella TJ
    Mol Endocrinol; 2008 Jan; 22(1):156-66. PubMed ID: 17872377
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides.
    Pioszak AA; Parker NR; Gardella TJ; Xu HE
    J Biol Chem; 2009 Oct; 284(41):28382-28391. PubMed ID: 19674967
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanisms of ligand binding to the parathyroid hormone (PTH)/PTH-related protein receptor: selectivity of a modified PTH(1-15) radioligand for GalphaS-coupled receptor conformations.
    Dean T; Linglart A; Mahon MJ; Bastepe M; Jüppner H; Potts JT; Gardella TJ
    Mol Endocrinol; 2006 Apr; 20(4):931-43. PubMed ID: 16339275
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biasing the parathyroid hormone receptor: relating in vitro ligand efficacy to in vivo biological activity.
    Appleton KM; Lee MH; Alele C; Alele C; Luttrell DK; Peterson YK; Morinelli TA; Luttrell LM
    Methods Enzymol; 2013; 522():229-62. PubMed ID: 23374189
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Current perspectives on parathyroid hormone (PTH) and PTH-related protein (PTHrP) as bone anabolic therapies.
    Esbrit P; Alcaraz MJ
    Biochem Pharmacol; 2013 May; 85(10):1417-23. PubMed ID: 23500550
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Histidine at position 5 is the specificity "switch" between two parathyroid hormone receptor subtypes.
    Behar V; Nakamoto C; Greenberg Z; Bisello A; Suva LJ; Rosenblatt M; Chorev M
    Endocrinology; 1996 Oct; 137(10):4217-24. PubMed ID: 8828480
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Physiological and Pharmacological Roles of PTH and PTHrP in Bone Using Their Shared Receptor, PTH1R.
    Martin TJ; Sims NA; Seeman E
    Endocr Rev; 2021 Jul; 42(4):383-406. PubMed ID: 33564837
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bone-related growth factors and zoledronic acid regulate the PTHrP/PTH.1 receptor bioregulation systems in MG-63 human osteosarcoma cells.
    Tenta R; Sourla A; Lembessis P; Koutsilieris M
    Anticancer Res; 2006; 26(1A):283-91. PubMed ID: 16475708
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Endogenous ligand recognition and structural transition of a human PTH receptor.
    Kobayashi K; Kawakami K; Kusakizako T; Miyauchi H; Tomita A; Kobayashi K; Shihoya W; Yamashita K; Nishizawa T; Kato HE; Inoue A; Nureki O
    Mol Cell; 2022 Sep; 82(18):3468-3483.e5. PubMed ID: 35932760
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The human PTH2 receptor: binding and signal transduction properties of the stably expressed recombinant receptor.
    Behar V; Pines M; Nakamoto C; Greenberg Z; Bisello A; Stueckle SM; Bessalle R; Usdin TB; Chorev M; Rosenblatt M; Suva LJ
    Endocrinology; 1996 Jul; 137(7):2748-57. PubMed ID: 8770894
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Investigational parathyroid hormone receptor analogs for the treatment of osteoporosis.
    Polyzos SA; Makras P; Efstathiadou Z; Anastasilakis AD
    Expert Opin Investig Drugs; 2015 Feb; 24(2):145-57. PubMed ID: 25316089
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tuberoinfundibular peptide (7-39) [TIP(7-39)], a novel, selective, high-affinity antagonist for the parathyroid hormone-1 receptor with no detectable agonist activity.
    Hoare SR; Usdin TB
    J Pharmacol Exp Ther; 2000 Nov; 295(2):761-70. PubMed ID: 11046116
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The extracellular amino-terminal region of the parathyroid hormone (PTH)/PTH-related peptide receptor determines the binding affinity for carboxyl-terminal fragments of PTH-(1-34).
    Jüppner H; Schipani E; Bringhurst FR; McClure I; Keutmann HT; Potts JT; Kronenberg HM; Abou-Samra AB; Segre GV; Gardella TJ
    Endocrinology; 1994 Feb; 134(2):879-84. PubMed ID: 8299582
    [TBL] [Abstract][Full Text] [Related]  

  • 19. International Union of Basic and Clinical Pharmacology. XCIII. The parathyroid hormone receptors--family B G protein-coupled receptors.
    Gardella TJ; Vilardaga JP
    Pharmacol Rev; 2015; 67(2):310-37. PubMed ID: 25713287
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cyclic adenosine monophosphate/protein kinase A mediates parathyroid hormone/parathyroid hormone-related protein receptor regulation of osteoclastogenesis and expression of RANKL and osteoprotegerin mRNAs by marrow stromal cells.
    Kondo H; Guo J; Bringhurst FR
    J Bone Miner Res; 2002 Sep; 17(9):1667-79. PubMed ID: 12211438
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.