BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

237 related articles for article (PubMed ID: 26565903)

  • 1. AKT1 Activation Promotes Development of Melanoma Metastases.
    Cho JH; Robinson JP; Arave RA; Burnett WJ; Kircher DA; Chen G; Davies MA; Grossmann AH; VanBrocklin MW; McMahon M; Holmen SL
    Cell Rep; 2015 Nov; 13(5):898-905. PubMed ID: 26565903
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State.
    Yoo JH; Brady SW; Acosta-Alvarez L; Rogers A; Peng J; Sorensen LK; Wolff RK; Mleynek T; Shin D; Rich CP; Kircher DA; Bild A; Odelberg SJ; Li DY; Holmen SL; Grossmann AH
    Cancer Res; 2019 Jun; 79(11):2892-2908. PubMed ID: 31048499
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Abl kinase regulation by BRAF/ERK and cooperation with Akt in melanoma.
    Jain A; Tripathi R; Turpin CP; Wang C; Plattner R
    Oncogene; 2017 Aug; 36(32):4585-4596. PubMed ID: 28368422
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Braf(V600E) cooperates with Pten loss to induce metastatic melanoma.
    Dankort D; Curley DP; Cartlidge RA; Nelson B; Karnezis AN; Damsky WE; You MJ; DePinho RA; McMahon M; Bosenberg M
    Nat Genet; 2009 May; 41(5):544-52. PubMed ID: 19282848
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of Braf(V600E)::Pten(-/-) melanoma.
    Scortegagna M; Ruller C; Feng Y; Lazova R; Kluger H; Li JL; De SK; Rickert R; Pellecchia M; Bosenberg M; Ronai ZA
    Oncogene; 2014 Aug; 33(34):4330-9. PubMed ID: 24037523
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of the mTOR pathway in ocular (uvea and conjunctiva) melanoma.
    Pópulo H; Soares P; Rocha AS; Silva P; Lopes JM
    Melanoma Res; 2010 Apr; 20(2):107-17. PubMed ID: 20173664
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RASSF6 exhibits promoter hypermethylation in metastatic melanoma and inhibits invasion in melanoma cells.
    Mezzanotte JJ; Hill V; Schmidt ML; Shinawi T; Tommasi S; Krex D; Schackert G; Pfeifer GP; Latif F; Clark GJ
    Epigenetics; 2014 Nov; 9(11):1496-503. PubMed ID: 25482183
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inside life of melanoma cell signaling, molecular insights, and therapeutic targets.
    Sosman JA; Margolin KA
    Curr Oncol Rep; 2009 Sep; 11(5):405-11. PubMed ID: 19679016
    [TBL] [Abstract][Full Text] [Related]  

  • 9. β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas.
    Damsky WE; Curley DP; Santhanakrishnan M; Rosenbaum LE; Platt JT; Gould Rothberg BE; Taketo MM; Dankort D; Rimm DL; McMahon M; Bosenberg M
    Cancer Cell; 2011 Dec; 20(6):741-54. PubMed ID: 22172720
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A detailed immunohistochemical analysis of the PI3K/AKT/mTOR pathway in lung cancer: correlation with PIK3CA, AKT1, K-RAS or PTEN mutational status and clinicopathological features.
    Trigka EA; Levidou G; Saetta AA; Chatziandreou I; Tomos P; Thalassinos N; Anastasiou N; Spartalis E; Kavantzas N; Patsouris E; Korkolopoulou P
    Oncol Rep; 2013 Aug; 30(2):623-36. PubMed ID: 23728071
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting mitogen-activated protein kinase/extracellular signal-regulated kinase kinase in the mutant (V600E) B-Raf signaling cascade effectively inhibits melanoma lung metastases.
    Sharma A; Tran MA; Liang S; Sharma AK; Amin S; Smith CD; Dong C; Robertson GP
    Cancer Res; 2006 Aug; 66(16):8200-9. PubMed ID: 16912199
    [TBL] [Abstract][Full Text] [Related]  

  • 12. AKT1
    Kircher DA; Trombetti KA; Silvis MR; Parkman GL; Fischer GM; Angel SN; Stehn CM; Strain SC; Grossmann AH; Duffy KL; Boucher KM; McMahon M; Davies MA; Mendoza MC; VanBrocklin MW; Holmen SL
    Mol Cancer Res; 2019 Sep; 17(9):1787-1800. PubMed ID: 31138602
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fibronectin induction abrogates the BRAF inhibitor response of BRAF V600E/PTEN-null melanoma cells.
    Fedorenko IV; Abel EV; Koomen JM; Fang B; Wood ER; Chen YA; Fisher KJ; Iyengar S; Dahlman KB; Wargo JA; Flaherty KT; Sosman JA; Sondak VK; Messina JL; Gibney GT; Smalley KS
    Oncogene; 2016 Mar; 35(10):1225-35. PubMed ID: 26073081
    [TBL] [Abstract][Full Text] [Related]  

  • 14. BRAF alterations are associated with complex mutational profiles in malignant melanoma.
    Daniotti M; Oggionni M; Ranzani T; Vallacchi V; Campi V; Di Stasi D; Torre GD; Perrone F; Luoni C; Suardi S; Frattini M; Pilotti S; Anichini A; Tragni G; Parmiani G; Pierotti MA; Rodolfo M
    Oncogene; 2004 Aug; 23(35):5968-77. PubMed ID: 15195137
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Specific gene expression signatures induced by the multiple oncogenic alterations that occur within the PTEN/PI3K/AKT pathway in lung cancer.
    De Marco C; Laudanna C; Rinaldo N; Oliveira DM; Ravo M; Weisz A; Ceccarelli M; Caira E; Rizzuto A; Zoppoli P; Malanga D; Viglietto G
    PLoS One; 2017; 12(6):e0178865. PubMed ID: 28662101
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cooperative interactions of PTEN deficiency and RAS activation in melanoma metastasis.
    Nogueira C; Kim KH; Sung H; Paraiso KH; Dannenberg JH; Bosenberg M; Chin L; Kim M
    Oncogene; 2010 Nov; 29(47):6222-32. PubMed ID: 20711233
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MAP kinase activity supported by BRAF (V600E) mutation rather than gene amplification is associated with ETV1 expression in melanoma brain metastases.
    Birner P; Berghoff AS; Dinhof C; Pirker C; Capper D; Schoppmann SF; Petzelbauer P; von Deimling A; Berger W; Preusser M
    Arch Dermatol Res; 2014 Dec; 306(10):873-84. PubMed ID: 25073704
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Exploration of genetic alterations in human endometrial cancer and melanoma: distinct tumorigenic pathways that share a frequent abnormal PI3K/AKT cascade.
    Ogawa K; Sun C; Horii A
    Oncol Rep; 2005 Dec; 14(6):1481-5. PubMed ID: 16273242
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of key-regulator genes in melanoma susceptibility and pathogenesis among patients from South Italy.
    Casula M; Muggiano A; Cossu A; Budroni M; Caracò C; Ascierto PA; Pagani E; Stanganelli I; Canzanella S; Sini M; Palomba G; ; Palmieri G
    BMC Cancer; 2009 Oct; 9():352. PubMed ID: 19799798
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PI3K Pathway Inhibition Achieves Potent Antitumor Activity in Melanoma Brain Metastases In Vitro and In Vivo.
    Niessner H; Schmitz J; Tabatabai G; Schmid AM; Calaminus C; Sinnberg T; Weide B; Eigentler TK; Garbe C; Schittek B; Quintanilla-Fend L; Bender B; Mai M; Praetorius C; Beissert S; Schackert G; Muders MH; Meinhardt M; Baretton GB; Dummer R; Flaherty K; Pichler BJ; Kulms D; Westphal D; Meier F
    Clin Cancer Res; 2016 Dec; 22(23):5818-5828. PubMed ID: 27307593
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.