These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

102 related articles for article (PubMed ID: 26568144)

  • 21. Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064.
    Akwabi-Ameyaw A; Bass JY; Caldwell RD; Caravella JA; Chen L; Creech KL; Deaton DN; Jones SA; Kaldor I; Liu Y; Madauss KP; Marr HB; McFadyen RB; Miller AB; Navas F; Parks DJ; Spearing PK; Todd D; Williams SP; Wisely GB
    Bioorg Med Chem Lett; 2008 Aug; 18(15):4339-43. PubMed ID: 18621523
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Knocking on FXR's door: the "hammerhead"-structure series of FXR agonists - amphiphilic isoxazoles with potent in vitro and in vivo activities.
    Gege C; Kinzel O; Steeneck C; Schulz A; Kremoser C
    Curr Top Med Chem; 2014; 14(19):2143-58. PubMed ID: 25388536
    [TBL] [Abstract][Full Text] [Related]  

  • 23. [Progress in the ligands and their complex structures of farnesoid X receptor].
    Li WH; Fu J; Zheng MY; Liu GX; Tang Y
    Yao Xue Xue Bao; 2012 Jun; 47(6):704-15. PubMed ID: 22919716
    [TBL] [Abstract][Full Text] [Related]  

  • 24. FXR activation improves myocardial fatty acid metabolism in a rodent model of obesity-driven cardiotoxicity.
    Mencarelli A; Cipriani S; Renga B; D'Amore C; Palladino G; Distrutti E; Baldelli F; Fiorucci S
    Nutr Metab Cardiovasc Dis; 2013 Feb; 23(2):94-101. PubMed ID: 21924881
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Conformationally constrained farnesoid X receptor (FXR) agonists: alternative replacements of the stilbene.
    Akwabi-Ameyaw A; Caravella JA; Chen L; Creech KL; Deaton DN; Madauss KP; Marr HB; Miller AB; Navas F; Parks DJ; Spearing PK; Todd D; Williams SP; Wisely GB
    Bioorg Med Chem Lett; 2011 Oct; 21(20):6154-60. PubMed ID: 21890356
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene.
    Bass JY; Caravella JA; Chen L; Creech KL; Deaton DN; Madauss KP; Marr HB; McFadyen RB; Miller AB; Mills WY; Navas F; Parks DJ; Smalley TL; Spearing PK; Todd D; Williams SP; Wisely GB
    Bioorg Med Chem Lett; 2011 Feb; 21(4):1206-13. PubMed ID: 21256005
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A formulation-enabled preclinical efficacy assessment of a farnesoid X receptor agonist, GW4064, in hamsters and cynomolgus monkeys.
    Chiang PC; Thompson DC; Ghosh S; Heitmeier MR
    J Pharm Sci; 2011 Nov; 100(11):4722-33. PubMed ID: 21660973
    [TBL] [Abstract][Full Text] [Related]  

  • 28. FXR agonist activity of conformationally constrained analogs of GW 4064.
    Akwabi-Ameyaw A; Bass JY; Caldwell RD; Caravella JA; Chen L; Creech KL; Deaton DN; Madauss KP; Marr HB; McFadyen RB; Miller AB; Navas F; Parks DJ; Spearing PK; Todd D; Williams SP; Bruce Wisely G
    Bioorg Med Chem Lett; 2009 Aug; 19(16):4733-9. PubMed ID: 19586769
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Farnesoid X receptor modulators: a patent review.
    Crawley ML
    Expert Opin Ther Pat; 2010 Aug; 20(8):1047-57. PubMed ID: 20569093
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Effects of isoxazolidine or triazolidine on rat serum lipids in vivo and LDL and HDL binding and degradation in human and rodent cultured cells in vitro.
    Hall IH; Wong OT; Simlot R; Izydore RA
    Res Commun Chem Pathol Pharmacol; 1992 Sep; 77(3):327-46. PubMed ID: 1333628
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The nuclear bile acid receptor FXR controls the liver derived tumor suppressor histidine-rich glycoprotein.
    Deuschle U; Birkel M; Hambruch E; Hornberger M; Kinzel O; Perović-Ottstadt S; Schulz A; Hahn U; Burnet M; Kremoser C
    Int J Cancer; 2015 Jun; 136(11):2693-704. PubMed ID: 25363753
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Activation of farnesoid X receptor attenuates hepatic injury in a murine model of alcoholic liver disease.
    Wu W; Zhu B; Peng X; Zhou M; Jia D; Gu J
    Biochem Biophys Res Commun; 2014 Jan; 443(1):68-73. PubMed ID: 24269813
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Discovery and optimization of 1,3,4-trisubstituted-pyrazolone derivatives as novel, potent, and nonsteroidal farnesoid X receptor (FXR) selective antagonists.
    Huang H; Yu Y; Gao Z; Zhang Y; Li C; Xu X; Jin H; Yan W; Ma R; Zhu J; Shen X; Jiang H; Chen L; Li J
    J Med Chem; 2012 Aug; 55(16):7037-53. PubMed ID: 22862148
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Discovery of a peroxisome proliferator activated receptor gamma (PPARgamma) modulator with balanced PPARalpha activity for the treatment of type 2 diabetes and dyslipidemia.
    Liu W; Liu K; Wood HB; McCann ME; Doebber TW; Chang CH; Akiyama TE; Einstein M; Berger JP; Meinke PT
    J Med Chem; 2009 Jul; 52(14):4443-53. PubMed ID: 19530681
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The high-fat high-fructose hamster as an animal model for niacin's biological activities in humans.
    Connolly BA; O'Connell DP; Lamon-Fava S; LeBlanc DF; Kuang YL; Schaefer EJ; Coppage AL; Benedict CR; Kiritsy CP; Bachovchin WW
    Metabolism; 2013 Dec; 62(12):1840-9. PubMed ID: 24035454
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The farnesoid X receptor induces very low density lipoprotein receptor gene expression.
    Sirvent A; Claudel T; Martin G; Brozek J; Kosykh V; Darteil R; Hum DW; Fruchart JC; Staels B
    FEBS Lett; 2004 May; 566(1-3):173-7. PubMed ID: 15147890
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Oats (Avena sativa) reduce atherogenesis in LDL-receptor-deficient mice.
    Andersson KE; Svedberg KA; Lindholm MW; Oste R; Hellstrand P
    Atherosclerosis; 2010 Sep; 212(1):93-9. PubMed ID: 20553794
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Identification of a chemical tool for the orphan nuclear receptor FXR.
    Maloney PR; Parks DJ; Haffner CD; Fivush AM; Chandra G; Plunket KD; Creech KL; Moore LB; Wilson JG; Lewis MC; Jones SA; Willson TM
    J Med Chem; 2000 Aug; 43(16):2971-4. PubMed ID: 10956205
    [No Abstract]   [Full Text] [Related]  

  • 39. Agonist of farnesoid X receptor protects against bile acid induced damage and oxidative stress in mouse placenta--a study on maternal cholestasis model.
    Wu WB; Xu YY; Cheng WW; Wang YX; Liu Y; Huang D; Zhang HJ
    Placenta; 2015 May; 36(5):545-51. PubMed ID: 25747729
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Pitavastatin: novel effects on lipid parameters.
    Chapman MJ
    Atheroscler Suppl; 2011 Nov; 12(3):277-84. PubMed ID: 22152282
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.