These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Heat shock protein 90 inhibitors induce cell differentiation via the ubiquitin-dependent aurora kinase A degradation in a MPLW515L mouse model of primary myelofibrosis. Wang F; Zhang H; He B; Liu Z; Wu X; Liu Y; Xu X; Gou X; Wang H; Yang Q Hematol Oncol; 2023 Aug; 41(3):474-486. PubMed ID: 36422297 [TBL] [Abstract][Full Text] [Related]
3. c-Myc Is a Major Determinant for Antitumor Activity of Aurora A Kinase Inhibitor MLN8237 in Thyroid Cancer. Li Y; Li X; Pu J; Yang Q; Guan H; Ji M; Shi B; Chen M; Hou P Thyroid; 2018 Dec; 28(12):1642-1654. PubMed ID: 30226440 [No Abstract] [Full Text] [Related]
4. Neoplastic fibrocytes play an essential role in bone marrow fibrosis in Jak2V617F-induced primary myelofibrosis mice. Ozono Y; Shide K; Kameda T; Kamiunten A; Tahira Y; Sekine M; Akizuki K; Nakamura K; Iwakiri H; Sueta M; Hidaka T; Kubuki Y; Yamamoto S; Hasuike S; Sawaguchi A; Nagata K; Shimoda K Leukemia; 2021 Feb; 35(2):454-467. PubMed ID: 32472085 [TBL] [Abstract][Full Text] [Related]
5. Molecular pathways: induction of polyploidy as a novel differentiation therapy for leukemia. Krause DS; Crispino JD Clin Cancer Res; 2013 Nov; 19(22):6084-8. PubMed ID: 23963861 [TBL] [Abstract][Full Text] [Related]
6. Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL. Wen Q; Goldenson B; Silver SJ; Schenone M; Dancik V; Huang Z; Wang LZ; Lewis TA; An WF; Li X; Bray MA; Thiollier C; Diebold L; Gilles L; Vokes MS; Moore CB; Bliss-Moreau M; Verplank L; Tolliday NJ; Mishra R; Vemula S; Shi J; Wei L; Kapur R; Lopez CK; Gerby B; Ballerini P; Pflumio F; Gilliland DG; Goldberg L; Birger Y; Izraeli S; Gamis AS; Smith FO; Woods WG; Taub J; Scherer CA; Bradner JE; Goh BC; Mercher T; Carpenter AE; Gould RJ; Clemons PA; Carr SA; Root DE; Schreiber SL; Stern AM; Crispino JD Cell; 2012 Aug; 150(3):575-89. PubMed ID: 22863010 [TBL] [Abstract][Full Text] [Related]
7. A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer. Dauch D; Rudalska R; Cossa G; Nault JC; Kang TW; Wuestefeld T; Hohmeyer A; Imbeaud S; Yevsa T; Hoenicke L; Pantsar T; Bozko P; Malek NP; Longerich T; Laufer S; Poso A; Zucman-Rossi J; Eilers M; Zender L Nat Med; 2016 Jul; 22(7):744-53. PubMed ID: 27213815 [TBL] [Abstract][Full Text] [Related]
8. Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells. Yuan CX; Zhou ZW; Yang YX; He ZX; Zhang X; Wang D; Yang T; Wang NJ; Zhao RJ; Zhou SF Drug Des Devel Ther; 2015; 9():487-508. PubMed ID: 25609923 [TBL] [Abstract][Full Text] [Related]
9. Primary myelofibrosis marrow-derived CD14+/CD34- monocytes induce myelofibrosis-like phenotype in immunodeficient mice and give rise to megakaryocytes. Manshouri T; Verstovsek S; Harris DM; Veletic I; Zhang X; Post SM; Bueso-Ramos CE; Estrov Z PLoS One; 2019; 14(9):e0222912. PubMed ID: 31569199 [TBL] [Abstract][Full Text] [Related]
11. Inhibition of Aurora A enhances radiosensitivity in selected lung cancer cell lines. Liu N; Wang YA; Sun Y; Ecsedy J; Sun J; Li X; Wang P Respir Res; 2019 Oct; 20(1):230. PubMed ID: 31647033 [TBL] [Abstract][Full Text] [Related]
13. Combination of Eribulin and Aurora A Inhibitor MLN8237 Prevents Metastatic Colonization and Induces Cytotoxic Autophagy in Breast Cancer. Kozyreva VK; Kiseleva AA; Ice RJ; Jones BC; Loskutov YV; Matalkah F; Smolkin MB; Marinak K; Livengood RH; Salkeni MA; Wen S; Hazard HW; Layne GP; Walsh CM; Cantrell PS; Kilby GW; Mahavadi S; Shah N; Pugacheva EN Mol Cancer Ther; 2016 Aug; 15(8):1809-22. PubMed ID: 27235164 [TBL] [Abstract][Full Text] [Related]
14. MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia. Pikman Y; Lee BH; Mercher T; McDowell E; Ebert BL; Gozo M; Cuker A; Wernig G; Moore S; Galinsky I; DeAngelo DJ; Clark JJ; Lee SJ; Golub TR; Wadleigh M; Gilliland DG; Levine RL PLoS Med; 2006 Jul; 3(7):e270. PubMed ID: 16834459 [TBL] [Abstract][Full Text] [Related]
15. Concurrent Inhibition of Neurosphere and Monolayer Cells of Pediatric Glioblastoma by Aurora A Inhibitor MLN8237 Predicted Survival Extension in PDOX Models. Kogiso M; Qi L; Braun FK; Injac SG; Zhang L; Du Y; Zhang H; Lin FY; Zhao S; Lindsay H; Su JM; Baxter PA; Adesina AM; Liao D; Qian MG; Berg S; Muscal JA; Li XN Clin Cancer Res; 2018 May; 24(9):2159-2170. PubMed ID: 29463553 [No Abstract] [Full Text] [Related]
16. Diagnosis, risk stratification, and response evaluation in classical myeloproliferative neoplasms. Rumi E; Cazzola M Blood; 2017 Feb; 129(6):680-692. PubMed ID: 28028026 [TBL] [Abstract][Full Text] [Related]
17. Inhibition of Aurora A Kinase in Combination with Chemotherapy Induces Synthetic Lethality and Overcomes Chemoresistance in Myc-Overexpressing Lymphoma. Park SI; Lin CP; Ren N; Angus SP; Dittmer DP; Foote M; Parton T; Bhatt AP; Fedoriw YD; Roth DP; Cann ML; Johnson GL; Damania B Target Oncol; 2019 Oct; 14(5):563-575. PubMed ID: 31429028 [TBL] [Abstract][Full Text] [Related]
18. Targeting Aurora kinase-A downregulates cell proliferation and angiogenesis in neuroblastoma. Romain C; Paul P; Kim KW; Lee S; Qiao J; Chung DH J Pediatr Surg; 2014 Jan; 49(1):159-65. PubMed ID: 24439602 [TBL] [Abstract][Full Text] [Related]
19. Efficacy of ALK5 inhibition in myelofibrosis. Yue L; Bartenstein M; Zhao W; Ho WT; Han Y; Murdun C; Mailloux AW; Zhang L; Wang X; Budhathoki A; Pradhan K; Rapaport F; Wang H; Shao Z; Ren X; Steidl U; Levine RL; Zhao ZJ; Verma A; Epling-Burnette PK JCI Insight; 2017 Apr; 2(7):e90932. PubMed ID: 28405618 [TBL] [Abstract][Full Text] [Related]
20. Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells. Ding YH; Zhou ZW; Ha CF; Zhang XY; Pan ST; He ZX; Edelman JL; Wang D; Yang YX; Zhang X; Duan W; Yang T; Qiu JX; Zhou SF Drug Des Devel Ther; 2015; 9():425-64. PubMed ID: 25624750 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]