BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 26574146)

  • 21. Effect of HNF4α genetic polymorphism G60D on the pharmacokinetics of CYP2D6 substrate tolterodine in healthy Korean individuals.
    Jiang F; Yeo CW; Lee SS; Oh MK; Ghim JL; Shon JH; Kim HS; Kim EY; Kim DH; Shin JG
    Pharmacogenet Genomics; 2013 Mar; 23(3):175-9. PubMed ID: 23292115
    [TBL] [Abstract][Full Text] [Related]  

  • 22. New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme.
    Wang B; Yang LP; Zhang XZ; Huang SQ; Bartlam M; Zhou SF
    Drug Metab Rev; 2009; 41(4):573-643. PubMed ID: 19645588
    [TBL] [Abstract][Full Text] [Related]  

  • 23. CYP2D6 polymorphism: implications for antipsychotic drug response, schizophrenia and personality traits.
    Dorado P; Peñas-Lledó EM; Llerena A
    Pharmacogenomics; 2007 Nov; 8(11):1597-608. PubMed ID: 18034624
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The CYP2D6 humanized mouse: effect of the human CYP2D6 transgene and HNF4alpha on the disposition of debrisoquine in the mouse.
    Corchero J; Granvil CP; Akiyama TE; Hayhurst GP; Pimprale S; Feigenbaum L; Idle JR; Gonzalez FJ
    Mol Pharmacol; 2001 Dec; 60(6):1260-7. PubMed ID: 11723233
    [TBL] [Abstract][Full Text] [Related]  

  • 25. High-Fat Diet Feeding Alters Expression of Hepatic Drug-Metabolizing Enzymes in Mice.
    Ning M; Jeong H
    Drug Metab Dispos; 2017 Jul; 45(7):707-711. PubMed ID: 28442500
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Substrate specific metabolism by polymorphic cytochrome P450 2D6 alleles.
    Bogni A; Monshouwer M; Moscone A; Hidestrand M; Ingelman-Sundberg M; Hartung T; Coecke S
    Toxicol In Vitro; 2005 Aug; 19(5):621-9. PubMed ID: 15893449
    [TBL] [Abstract][Full Text] [Related]  

  • 27. V79 Chinese hamster cells genetically engineered for polymorphic cytochrome P450 2D6 and their predictive value for humans.
    Krebsfaenger N; Mürdter TE; Zanger UM; Eichelbaum MF; Doehmer J
    ALTEX; 2003; 20(3):143-54. PubMed ID: 12947487
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Human liver cytochrome P450 2D6 genotype, full-length messenger ribonucleic acid, and activity assessed with a novel cytochrome P450 2D6 substrate.
    McConnachie L; Bodor M; Kowdley K; Levy A; Tung B; Thummel K; Phillips B; Bajpai M; Chi V; Esmay JD; Shen DD; Ho RJ
    Clin Pharmacol Ther; 2004 Apr; 75(4):282-97. PubMed ID: 15060507
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Decreased nuclear receptor activity and epigenetic modulation associates with down-regulation of hepatic drug-metabolizing enzymes in chronic kidney disease.
    Velenosi TJ; Feere DA; Sohi G; Hardy DB; Urquhart BL
    FASEB J; 2014 Dec; 28(12):5388-97. PubMed ID: 25208844
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Genetic polymorphism of cytochrome P450 2D6 determines oestrogen receptor activity of the major infertility drug clomiphene via its active metabolites.
    Mürdter TE; Kerb R; Turpeinen M; Schroth W; Ganchev B; Böhmer GM; Igel S; Schaeffeler E; Zanger U; Brauch H; Schwab M
    Hum Mol Genet; 2012 Mar; 21(5):1145-54. PubMed ID: 22108178
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Differences in the Epigenetic Regulation of Cytochrome P450 Genes between Human Embryonic Stem Cell-Derived Hepatocytes and Primary Hepatocytes.
    Park HJ; Choi YJ; Kim JW; Chun HS; Im I; Yoon S; Han YM; Song CW; Kim H
    PLoS One; 2015; 10(7):e0132992. PubMed ID: 26177506
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Computational predictions of the site of metabolism of cytochrome P450 2D6 substrates: comparative analysis, molecular docking, bioactivation and toxicological implications.
    Ford KA; Ryslik G; Sodhi J; Halladay J; Diaz D; Dambach D; Masuda M
    Drug Metab Rev; 2015 Aug; 47(3):291-319. PubMed ID: 26024250
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Expression, purification, biochemical characterization, and comparative function of human cytochrome P450 2D6.1, 2D6.2, 2D6.10, and 2D6.17 allelic isoforms.
    Yu A; Kneller BM; Rettie AE; Haining RL
    J Pharmacol Exp Ther; 2002 Dec; 303(3):1291-300. PubMed ID: 12438554
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Negative autoregulation of HNF-4alpha gene expression by HNF-4alpha1.
    Magenheim J; Hertz R; Berman I; Nousbeck J; Bar-Tana J
    Biochem J; 2005 May; 388(Pt 1):325-32. PubMed ID: 15651981
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Complexities of CYP2D6 gene analysis and interpretation.
    Gaedigk A
    Int Rev Psychiatry; 2013 Oct; 25(5):534-53. PubMed ID: 24151800
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The human organic cation transporter-1 gene is transactivated by hepatocyte nuclear factor-4alpha.
    Saborowski M; Kullak-Ublick GA; Eloranta JJ
    J Pharmacol Exp Ther; 2006 May; 317(2):778-85. PubMed ID: 16436500
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The impact of the CYP2D6 polymorphism on haloperidol pharmacokinetics and on the outcome of haloperidol treatment.
    Brockmöller J; Kirchheiner J; Schmider J; Walter S; Sachse C; Müller-Oerlinghausen B; Roots I
    Clin Pharmacol Ther; 2002 Oct; 72(4):438-52. PubMed ID: 12386646
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Nrf2 Regulates the Expression of
    Siswanto FM; Handayani MDN; Firmasyah RD; Oguro A; Imaoka S
    Curr Drug Metab; 2023; 24(9):667-681. PubMed ID: 37916628
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Physiological Regulation of Drug Metabolism and Transport: Pregnancy, Microbiome, Inflammation, Infection, and Fasting.
    Morgan ET; Dempsey JL; Mimche SM; Lamb TJ; Kulkarni S; Cui JY; Jeong H; Slitt AL
    Drug Metab Dispos; 2018 May; 46(5):503-513. PubMed ID: 29514828
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Functional analysis of CYP2D6.31 variant: homology modeling suggests possible disruption of redox partner interaction by Arg440His substitution.
    Allorge D; Bréant D; Harlow J; Chowdry J; Lo-Guidice JM; Chevalier D; Cauffiez C; Lhermitte M; Blaney FE; Tucker GT; Broly F; Ellis SW
    Proteins; 2005 May; 59(2):339-46. PubMed ID: 15726636
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.