BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 26575390)

  • 1. Computer-assisted designed "selenoxy-chinolin": a new catalytic mechanism of the GPx-like cycle and inhibition of metal-free and metal-associated Aβ aggregation.
    Wang Z; Wang Y; Li W; Liu Z; Luo Z; Sun Y; Wu R; Huang L; Li X
    Dalton Trans; 2015 Dec; 44(48):20913-25. PubMed ID: 26575390
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological evaluation of a new series of ebselen derivatives as glutathione peroxidase (GPx) mimics and cholinesterase inhibitors against Alzheimer's disease.
    Luo Z; Liang L; Sheng J; Pang Y; Li J; Huang L; Li X
    Bioorg Med Chem; 2014 Feb; 22(4):1355-61. PubMed ID: 24461494
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional mimics of glutathione peroxidase: bioinspired synthetic antioxidants.
    Bhabak KP; Mugesh G
    Acc Chem Res; 2010 Nov; 43(11):1408-19. PubMed ID: 20690615
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Unusual Cyclodextrin Derivatives as a New Avenue to Modulate Self- and Metal-Induced Aβ Aggregation.
    Oliveri V; Bellia F; Pietropaolo A; Vecchio G
    Chemistry; 2015 Sep; 21(40):14047-59. PubMed ID: 26298549
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and evaluation of 8-hydroxyquinolin derivatives substituted with (benzo[d][1,2]selenazol-3(2H)-one) as effective inhibitor of metal-induced Aβ aggregation and antioxidant.
    Wang B; Wang Z; Chen H; Lu CJ; Li X
    Bioorg Med Chem; 2016 Oct; 24(19):4741-4749. PubMed ID: 27567080
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The ongoing search for small molecules to study metal-associated amyloid-β species in Alzheimer's disease.
    Savelieff MG; DeToma AS; Derrick JS; Lim MH
    Acc Chem Res; 2014 Aug; 47(8):2475-82. PubMed ID: 25080056
    [TBL] [Abstract][Full Text] [Related]  

  • 7. New multi-target-directed small molecules against Alzheimer's disease: a combination of resveratrol and clioquinol.
    Mao F; Yan J; Li J; Jia X; Miao H; Sun Y; Huang L; Li X
    Org Biomol Chem; 2014 Aug; 12(31):5936-44. PubMed ID: 24986600
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antioxidant activity of the anti-inflammatory compound ebselen: a reversible cyclization pathway via selenenic and seleninic acid intermediates.
    Sarma BK; Mugesh G
    Chemistry; 2008; 14(34):10603-14. PubMed ID: 18932179
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, and evaluation of multitarget-directed selenium-containing clioquinol derivatives for the treatment of Alzheimer's disease.
    Wang Z; Wang Y; Li W; Mao F; Sun Y; Huang L; Li X
    ACS Chem Neurosci; 2014 Oct; 5(10):952-62. PubMed ID: 25121395
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glutathione peroxidase (GPx)-like antioxidant activity of the organoselenium drug ebselen: unexpected complications with thiol exchange reactions.
    Sarma BK; Mugesh G
    J Am Chem Soc; 2005 Aug; 127(32):11477-85. PubMed ID: 16089478
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Multitarget-directed benzylideneindanone derivatives: anti-β-amyloid (Aβ) aggregation, antioxidant, metal chelation, and monoamine oxidase B (MAO-B) inhibition properties against Alzheimer's disease.
    Huang L; Lu C; Sun Y; Mao F; Luo Z; Su T; Jiang H; Shan W; Li X
    J Med Chem; 2012 Oct; 55(19):8483-92. PubMed ID: 22978824
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, characterization, and antioxidant activity of some ebselen analogues.
    Bhabak KP; Mugesh G
    Chemistry; 2007; 13(16):4594-601. PubMed ID: 17299817
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties.
    Fernández-Bachiller MI; Pérez C; González-Muñoz GC; Conde S; López MG; Villarroya M; García AG; Rodríguez-Franco MI
    J Med Chem; 2010 Jul; 53(13):4927-37. PubMed ID: 20545360
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel 8-Hydroxyquinoline Derivatives as Multitarget Compounds for the Treatment of Alzheimer's Disease.
    Prati F; Bergamini C; Fato R; Soukup O; Korabecny J; Andrisano V; Bartolini M; Bolognesi ML
    ChemMedChem; 2016 Jun; 11(12):1284-95. PubMed ID: 26880501
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Lan JS; Xie SS; Li SY; Pan LF; Wang XB; Kong LY
    Bioorg Med Chem; 2014 Nov; 22(21):6089-104. PubMed ID: 25282654
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis, and evaluation of multitarget-directed resveratrol derivatives for the treatment of Alzheimer's disease.
    Lu C; Guo Y; Yan J; Luo Z; Luo HB; Yan M; Huang L; Li X
    J Med Chem; 2013 Jul; 56(14):5843-59. PubMed ID: 23799643
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, Synthesis, and Evaluation of Orally Available Clioquinol-Moracin M Hybrids as Multitarget-Directed Ligands for Cognitive Improvement in a Rat Model of Neurodegeneration in Alzheimer's Disease.
    Wang Z; Wang Y; Wang B; Li W; Huang L; Li X
    J Med Chem; 2015 Nov; 58(21):8616-37. PubMed ID: 26473791
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel 8-hydroxyquinoline derivatives targeting β-amyloid aggregation, metal chelation and oxidative stress against Alzheimer's disease.
    Yang X; Cai P; Liu Q; Wu J; Yin Y; Wang X; Kong L
    Bioorg Med Chem; 2018 Jul; 26(12):3191-3201. PubMed ID: 29729985
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New Hydroxyquinoline-Based Derivatives as Potent Modulators of Amyloid-β Aggregations.
    Fu CL; Hsu LS; Liao YF; Hu MK
    Arch Pharm (Weinheim); 2016 May; 349(5):327-41. PubMed ID: 27027880
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and evaluation of multi-target-directed ligands against Alzheimer's disease based on the fusion of donepezil and ebselen.
    Luo Z; Sheng J; Sun Y; Lu C; Yan J; Liu A; Luo HB; Huang L; Li X
    J Med Chem; 2013 Nov; 56(22):9089-99. PubMed ID: 24160297
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.