739 related articles for article (PubMed ID: 26579458)
1. Discovery of direct inhibitors of Keap1-Nrf2 protein-protein interaction as potential therapeutic and preventive agents.
Abed DA; Goldstein M; Albanyan H; Jin H; Hu L
Acta Pharm Sin B; 2015 Jul; 5(4):285-99. PubMed ID: 26579458
[TBL] [Abstract][Full Text] [Related]
2. Development of a Homogeneous Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) Assay for the Inhibition of Keap1-Nrf2 Protein-Protein Interaction.
Lee S; Abed DA; Beamer LJ; Hu L
SLAS Discov; 2021 Jan; 26(1):100-112. PubMed ID: 32564647
[TBL] [Abstract][Full Text] [Related]
3. Reprint of: Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs.
Satoh T; McKercher SR; Lipton SA
Free Radic Biol Med; 2014 Jan; 66():45-57. PubMed ID: 24262357
[TBL] [Abstract][Full Text] [Related]
4. Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs.
Satoh T; McKercher SR; Lipton SA
Free Radic Biol Med; 2013 Dec; 65():645-657. PubMed ID: 23892355
[TBL] [Abstract][Full Text] [Related]
5. Regulation of Keap1-Nrf2 axis in temporal lobe epilepsy-hippocampal sclerosis patients may limit the seizure outcomes.
Kishore M; Pradeep M; Narne P; Jayalakshmi S; Panigrahi M; Patil A; Babu PP
Neurol Sci; 2023 Dec; 44(12):4441-4450. PubMed ID: 37432566
[TBL] [Abstract][Full Text] [Related]
6. Nuclear factor (erythroid-derived 2)-like 2 (NRF2) drug discovery: Biochemical toolbox to develop NRF2 activators by reversible binding of Kelch-like ECH-associated protein 1 (KEAP1).
Bresciani A; Missineo A; Gallo M; Cerretani M; Fezzardi P; Tomei L; Cicero DO; Altamura S; Santoprete A; Ingenito R; Bianchi E; Pacifici R; Dominguez C; Munoz-Sanjuan I; Harper S; Toledo-Sherman L; Park LC
Arch Biochem Biophys; 2017 Oct; 631():31-41. PubMed ID: 28801166
[TBL] [Abstract][Full Text] [Related]
7. Effects of 4-hydroxynonenal on vascular endothelial and smooth muscle cell redox signaling and function in health and disease.
Chapple SJ; Cheng X; Mann GE
Redox Biol; 2013 May; 1(1):319-31. PubMed ID: 24024167
[TBL] [Abstract][Full Text] [Related]
8. l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats.
Wang Z; Liang M; Li H; Cai L; He H; Wu Q; Yang L
J Sci Food Agric; 2019 Aug; 99(10):4849-4862. PubMed ID: 31001831
[TBL] [Abstract][Full Text] [Related]
9. Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals.
Surh YJ; Kundu JK; Na HK
Planta Med; 2008 Oct; 74(13):1526-39. PubMed ID: 18937164
[TBL] [Abstract][Full Text] [Related]
10. Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains.
Ogura T; Tong KI; Mio K; Maruyama Y; Kurokawa H; Sato C; Yamamoto M
Proc Natl Acad Sci U S A; 2010 Feb; 107(7):2842-7. PubMed ID: 20133743
[TBL] [Abstract][Full Text] [Related]
11. Nrf2 activator via interference of Nrf2-Keap1 interaction has antioxidant and anti-inflammatory properties in Parkinson's disease animal model.
Kim S; Indu Viswanath AN; Park JH; Lee HE; Park AY; Choi JW; Kim HJ; Londhe AM; Jang BK; Lee J; Hwang H; Lim SM; Pae AN; Park KD
Neuropharmacology; 2020 May; 167():107989. PubMed ID: 32032607
[TBL] [Abstract][Full Text] [Related]
12. Screening approaches for the identification of Nrf2-Keap1 protein-protein interaction inhibitors targeting hot spot residues.
Asano W; Hantani R; Uhara T; Debaene F; Nomura A; Yamaguchi K; Adachi T; Otake K; Harada K; Hantani Y
SLAS Discov; 2024 Mar; 29(2):100125. PubMed ID: 37935317
[TBL] [Abstract][Full Text] [Related]
13. Ginnalin A Binds to the Subpockets of Keap1 Kelch Domain To Activate the Nrf2-Regulated Antioxidant Defense System in SH-SY5Y Cells.
Zhang Z; Peng L; Fu Y; Wang W; Wang P; Zhou F
ACS Chem Neurosci; 2021 Mar; 12(5):872-882. PubMed ID: 33571414
[TBL] [Abstract][Full Text] [Related]
14. Response of Cytoprotective and Detoxifying Proteins to Vanadate and/or Magnesium in the Rat Liver: The Nrf2-Keap1 System.
Ścibior A; Wojda I; Wnuk E; Pietrzyk Ł; Plewa Z
Oxid Med Cell Longev; 2021; 2021():8447456. PubMed ID: 34950419
[TBL] [Abstract][Full Text] [Related]
15. Updated research and applications of small molecule inhibitors of Keap1-Nrf2 protein-protein interaction: a review.
Zhuang C; Miao Z; Sheng C; Zhang W
Curr Med Chem; 2014; 21(16):1861-70. PubMed ID: 24533814
[TBL] [Abstract][Full Text] [Related]
16. Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery.
Davies TG; Wixted WE; Coyle JE; Griffiths-Jones C; Hearn K; McMenamin R; Norton D; Rich SJ; Richardson C; Saxty G; Willems HM; Woolford AJ; Cottom JE; Kou JP; Yonchuk JG; Feldser HG; Sanchez Y; Foley JP; Bolognese BJ; Logan G; Podolin PL; Yan H; Callahan JF; Heightman TD; Kerns JK
J Med Chem; 2016 Apr; 59(8):3991-4006. PubMed ID: 27031670
[TBL] [Abstract][Full Text] [Related]
17. Nrf2 activation through the inhibition of Keap1-Nrf2 protein-protein interaction.
Lee S; Hu L
Med Chem Res; 2020 May; 29(5):846-867. PubMed ID: 32390710
[TBL] [Abstract][Full Text] [Related]
18. Docosahexaenoic Acid Induces Expression of NAD(P)H: Quinone Oxidoreductase and Heme Oxygenase-1 through Activation of Nrf2 in Cerulein-Stimulated Pancreatic Acinar Cells.
Ahn YJ; Lim JW; Kim H
Antioxidants (Basel); 2020 Nov; 9(11):. PubMed ID: 33158207
[TBL] [Abstract][Full Text] [Related]
19. Curcumin attenuates oxidative stress in RAW264.7 cells by increasing the activity of antioxidant enzymes and activating the Nrf2-Keap1 pathway.
Lin X; Bai D; Wei Z; Zhang Y; Huang Y; Deng H; Huang X
PLoS One; 2019; 14(5):e0216711. PubMed ID: 31112588
[TBL] [Abstract][Full Text] [Related]
20. Effects of zearalenone-induced oxidative stress and Keap1-Nrf2 signaling pathway-related gene expression in the ileum and mesenteric lymph nodes of post-weaning gilts.
Cheng Q; Jiang S; Huang L; Wang Y; Yang W; Yang Z; Ge J
Toxicology; 2020 Jan; 429():152337. PubMed ID: 31760079
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
