BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1444 related articles for article (PubMed ID: 26580601)

  • 1. Danusertib Induces Apoptosis, Cell Cycle Arrest, and Autophagy but Inhibits Epithelial to Mesenchymal Transition Involving PI3K/Akt/mTOR Signaling Pathway in Human Ovarian Cancer Cells.
    Zi D; Zhou ZW; Yang YJ; Huang L; Zhou ZL; He SM; He ZX; Zhou SF
    Int J Mol Sci; 2015 Nov; 16(11):27228-51. PubMed ID: 26580601
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and NCI-N78 cells.
    Yuan CX; Zhou ZW; Yang YX; He ZX; Zhang X; Wang D; Yang T; Pan SY; Chen XW; Zhou SF
    Drug Des Devel Ther; 2015; 9():1293-318. PubMed ID: 25767376
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The pan-inhibitor of Aurora kinases danusertib induces apoptosis and autophagy and suppresses epithelial-to-mesenchymal transition in human breast cancer cells.
    Li JP; Yang YX; Liu QL; Zhou ZW; Pan ST; He ZX; Zhang X; Yang T; Pan SY; Duan W; He SM; Chen XW; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1027-62. PubMed ID: 25733818
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells.
    Wang F; Li H; Yan XG; Zhou ZW; Yi ZG; He ZX; Pan ST; Yang YX; Wang ZZ; Zhang X; Yang T; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():575-601. PubMed ID: 25632225
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells.
    Ding YH; Zhou ZW; Ha CF; Zhang XY; Pan ST; He ZX; Edelman JL; Wang D; Yang YX; Zhang X; Duan W; Yang T; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():425-64. PubMed ID: 25624750
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells.
    Ren BJ; Zhou ZW; Zhu DJ; Ju YL; Wu JH; Ouyang MZ; Chen XW; Zhou SF
    Int J Mol Sci; 2015 Dec; 17(1):. PubMed ID: 26729093
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells.
    Wang F; Wang Q; Zhou ZW; Yu SN; Pan ST; He ZX; Zhang X; Wang D; Yang YX; Yang T; Sun T; Li M; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():537-60. PubMed ID: 25632222
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK; Wang ZL; Pan ST; Ding HQ; Au GH; He ZX; Zhou ZW; Xiao G; Yang YX; Zhang X; Yang T; Chen XW; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1555-84. PubMed ID: 25792811
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of Aurora kinases induces apoptosis and autophagy via AURKB/p70S6K/RPL15 axis in human leukemia cells.
    He SJ; Shu LP; Zhou ZW; Yang T; Duan W; Zhang X; He ZX; Zhou SF
    Cancer Lett; 2016 Nov; 382(2):215-230. PubMed ID: 27612557
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.
    Yuan CX; Zhou ZW; Yang YX; He ZX; Zhang X; Wang D; Yang T; Wang NJ; Zhao RJ; Zhou SF
    Drug Des Devel Ther; 2015; 9():487-508. PubMed ID: 25609923
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Effect of danusertib on cell cycle, apoptosis and autophagy of hepatocellular carcinoma HepG2 cells
    Zhu Q; Luo M; Zhou C; Chen Z; Huang W; Huang J; Zhao S; Yu X
    Nan Fang Yi Ke Da Xue Xue Bao; 2018 Dec; 38(12):1476-1484. PubMed ID: 30613017
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.
    Pan ST; Qin Y; Zhou ZW; He ZX; Zhang X; Yang T; Yang YX; Wang D; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1601-26. PubMed ID: 25834400
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of PI3K/Akt/mTOR signaling pathway alleviates ovarian cancer chemoresistance through reversing epithelial-mesenchymal transition and decreasing cancer stem cell marker expression.
    Deng J; Bai X; Feng X; Ni J; Beretov J; Graham P; Li Y
    BMC Cancer; 2019 Jun; 19(1):618. PubMed ID: 31234823
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells.
    Li JP; Yang YX; Liu QL; Pan ST; He ZX; Zhang X; Yang T; Chen XW; Wang D; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1627-52. PubMed ID: 25834401
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance in human ovarian cancer cells.
    Hu JL; Hu XL; Guo AY; Wang CJ; Wen YY; Cang SD
    Oncotarget; 2017 Jul; 8(30):49380-49394. PubMed ID: 28537902
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Augmentation of danusertib's anticancer activity against melanoma by blockage of autophagy.
    Shang YY; Yu N; Xia L; Yu YY; Ma CM; Jiao YN; Li YF; Wang Y; Dang J; Li W
    Drug Deliv Transl Res; 2020 Feb; 10(1):136-145. PubMed ID: 31625025
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tanshinone I attenuates the malignant biological properties of ovarian cancer by inducing apoptosis and autophagy via the inactivation of PI3K/AKT/mTOR pathway.
    Zhou J; Jiang YY; Chen H; Wu YC; Zhang L
    Cell Prolif; 2020 Feb; 53(2):e12739. PubMed ID: 31820522
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pectolinarigenin Induced Cell Cycle Arrest, Autophagy, and Apoptosis in Gastric Cancer Cell via PI3K/AKT/mTOR Signaling Pathway.
    Lee HJ; Venkatarame Gowda Saralamma V; Kim SM; Ha SE; Raha S; Lee WS; Kim EH; Lee SJ; Heo JD; Kim GS
    Nutrients; 2018 Aug; 10(8):. PubMed ID: 30096805
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Luteoloside induces G
    Zhou M; Shen S; Zhao X; Gong X
    Biochem Biophys Res Commun; 2017 Dec; 494(1-2):263-269. PubMed ID: 29024631
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Asiatic acid exerts anticancer potential in human ovarian cancer cells via suppression of PI3K/Akt/mTOR signalling.
    Ren L; Cao QX; Zhai FR; Yang SQ; Zhang HX
    Pharm Biol; 2016 Nov; 54(11):2377-2382. PubMed ID: 26984021
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 73.