These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 26581123)

  • 1. Quantification of adenosine A(1) receptor biased agonism: Implications for drug discovery.
    Baltos JA; Gregory KJ; White PJ; Sexton PM; Christopoulos A; May LT
    Biochem Pharmacol; 2016 Jan; 99():101-12. PubMed ID: 26581123
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Capadenoson, a clinically trialed partial adenosine A
    Baltos JA; Vecchio EA; Harris MA; Qin CX; Ritchie RH; Christopoulos A; White PJ; May LT
    Biochem Pharmacol; 2017 Jul; 135():79-89. PubMed ID: 28344125
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel Irreversible Agonists Acting at the A
    Jörg M; Glukhova A; Abdul-Ridha A; Vecchio EA; Nguyen AT; Sexton PM; White PJ; May LT; Christopoulos A; Scammells PJ
    J Med Chem; 2016 Dec; 59(24):11182-11194. PubMed ID: 27958734
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Separation of on-target efficacy from adverse effects through rational design of a bitopic adenosine receptor agonist.
    Valant C; May LT; Aurelio L; Chuo CH; White PJ; Baltos JA; Sexton PM; Scammells PJ; Christopoulos A
    Proc Natl Acad Sci U S A; 2014 Mar; 111(12):4614-9. PubMed ID: 24619092
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Structure-Activity Relationship Study of Bitopic N
    Aurelio L; Baltos JA; Ford L; Nguyen ATN; Jörg M; Devine SM; Valant C; White PJ; Christopoulos A; May LT; Scammells PJ
    J Med Chem; 2018 Mar; 61(5):2087-2103. PubMed ID: 29446948
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design and pharmacological profile of a novel covalent partial agonist for the adenosine A
    Yang X; Dilweg MA; Osemwengie D; Burggraaff L; van der Es D; Heitman LH; IJzerman AP
    Biochem Pharmacol; 2020 Oct; 180():114144. PubMed ID: 32653590
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Extracellular Loop 2 of the Adenosine A1 Receptor Has a Key Role in Orthosteric Ligand Affinity and Agonist Efficacy.
    Nguyen AT; Baltos JA; Thomas T; Nguyen TD; Muñoz LL; Gregory KJ; White PJ; Sexton PM; Christopoulos A; May LT
    Mol Pharmacol; 2016 Dec; 90(6):703-714. PubMed ID: 27683014
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The effect of two selective A
    Cooper SL; March J; Sabbatini AR; Hill SJ; Jörg M; Scammells PJ; Woolard J
    Br J Pharmacol; 2020 Jan; 177(2):346-359. PubMed ID: 31596949
    [TBL] [Abstract][Full Text] [Related]  

  • 9. VCP746, a novel A1 adenosine receptor biased agonist, reduces hypertrophy in a rat neonatal cardiac myocyte model.
    Chuo CH; Devine SM; Scammells PJ; Krum H; Christopoulos A; May LT; White PJ; Wang BH
    Clin Exp Pharmacol Physiol; 2016 Oct; 43(10):976-82. PubMed ID: 27377874
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The hybrid molecule, VCP746, is a potent adenosine A2B receptor agonist that stimulates anti-fibrotic signalling.
    Vecchio EA; Chuo CH; Baltos JA; Ford L; Scammells PJ; Wang BH; Christopoulos A; White PJ; May LT
    Biochem Pharmacol; 2016 Oct; 117():46-56. PubMed ID: 27520486
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and characterization of novel 2-amino-3-benzoylthiophene derivatives as biased allosteric agonists and modulators of the adenosine A(1) receptor.
    Valant C; Aurelio L; Devine SM; Ashton TD; White JM; Sexton PM; Christopoulos A; Scammells PJ
    J Med Chem; 2012 Mar; 55(5):2367-75. PubMed ID: 22315963
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Current status of A1 adenosine receptor allosteric enhancers.
    Romagnoli R; Baraldi PG; Moorman AR; Borea PA; Varani K
    Future Med Chem; 2015; 7(10):1247-59. PubMed ID: 26144263
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and in Vivo Characterization of A
    Tosh DK; Rao H; Bitant A; Salmaso V; Mannes P; Lieberman DI; Vaughan KL; Mattison JA; Rothwell AC; Auchampach JA; Ciancetta A; Liu N; Cui Z; Gao ZG; Reitman ML; Gavrilova O; Jacobson KA
    J Med Chem; 2019 Feb; 62(3):1502-1522. PubMed ID: 30605331
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of the Second Extracellular Loop of the Adenosine A1 Receptor on Allosteric Modulator Binding, Signaling, and Cooperativity.
    Nguyen AT; Vecchio EA; Thomas T; Nguyen TD; Aurelio L; Scammells PJ; White PJ; Sexton PM; Gregory KJ; May LT; Christopoulos A
    Mol Pharmacol; 2016 Dec; 90(6):715-725. PubMed ID: 27683013
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pharmacological Insights Into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure.
    Rueda P; Merlin J; Chimenti S; Feletou M; Paysant J; White PJ; Christopoulos A; Sexton PM; Summers RJ; Charman WN; May LT; Langmead CJ
    Front Pharmacol; 2021; 12():628060. PubMed ID: 33776771
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 4-amino-6-alkyloxy-2-alkylthiopyrimidine derivatives as novel non-nucleoside agonists for the adenosine A
    Cosimelli B; Greco G; Laneri S; Novellino E; Sacchi A; Trincavelli ML; Giacomelli C; Taliani S; Da Settimo F; Martini C
    Chem Biol Drug Des; 2016 Nov; 88(5):724-729. PubMed ID: 27282729
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural Basis for Binding of Allosteric Drug Leads in the Adenosine A
    Miao Y; Bhattarai A; Nguyen ATN; Christopoulos A; May LT
    Sci Rep; 2018 Nov; 8(1):16836. PubMed ID: 30442899
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Examining the Role of the Linker in Bitopic
    Awalt JK; Nguyen ATN; Fyfe TJ; Thai BS; White PJ; Christopoulos A; Jörg M; May LT; Scammells PJ
    J Med Chem; 2022 Jul; 65(13):9076-9095. PubMed ID: 35729775
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Adenosine A1 receptors heterodimerize with β1- and β2-adrenergic receptors creating novel receptor complexes with altered G protein coupling and signaling.
    Chandrasekera PC; Wan TC; Gizewski ET; Auchampach JA; Lasley RD
    Cell Signal; 2013 Apr; 25(4):736-42. PubMed ID: 23291003
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modulation of insulin release by adenosine A1 receptor agonists and antagonists in INS-1 cells: the possible contribution of 86Rb+ efflux and 45Ca2+ uptake.
    Töpfer M; Burbiel CE; Müller CE; Knittel J; Verspohl EJ
    Cell Biochem Funct; 2008 Dec; 26(8):833-43. PubMed ID: 18979526
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.