217 related articles for article (PubMed ID: 26582916)
1. Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity.
Virgilio A; Petraccone L; Vellecco V; Bucci M; Varra M; Irace C; Santamaria R; Pepe A; Mayol L; Esposito V; Galeone A
Nucleic Acids Res; 2015 Dec; 43(22):10602-11. PubMed ID: 26582916
[TBL] [Abstract][Full Text] [Related]
2. 5-Hydroxymethyl-2'-deoxyuridine residues in the thrombin binding aptamer: investigating anticoagulant activity by making a tiny chemical modification.
Virgilio A; Petraccone L; Scuotto M; Vellecco V; Bucci M; Mayol L; Varra M; Esposito V; Galeone A
Chembiochem; 2014 Nov; 15(16):2427-34. PubMed ID: 25214456
[TBL] [Abstract][Full Text] [Related]
3. The "Janus face" of the thrombin binding aptamer: Investigating the anticoagulant and antiproliferative properties through straightforward chemical modifications.
Esposito V; Russo A; Amato T; Vellecco V; Bucci M; Mayol L; Russo G; Virgilio A; Galeone A
Bioorg Chem; 2018 Feb; 76():202-209. PubMed ID: 29190476
[TBL] [Abstract][Full Text] [Related]
4. Improving Thermodynamic Stability and Anticoagulant Activity of a Thrombin Binding Aptamer by Incorporation of 8-trifluoromethyl-2'-deoxyguanosine.
Bao HL; Ishizuka T; Yamashita A; Furukoji E; Asada Y; Xu Y
J Med Chem; 2021 Jan; 64(1):711-718. PubMed ID: 33289557
[TBL] [Abstract][Full Text] [Related]
5. Anomeric DNA quadruplexes.
Kolganova NA; Varizhuk AM; Novikov RA; Florentiev VL; Pozmogova GE; Borisova OF; Shchyolkina AK; Smirnov IP; Kaluzhny DN; Timofeev EN
Artif DNA PNA XNA; 2014; 5(2):e28422. PubMed ID: 25483931
[TBL] [Abstract][Full Text] [Related]
6. Structural properties and anticoagulant/cytotoxic activities of heterochiral enantiomeric thrombin binding aptamer (TBA) derivatives.
Virgilio A; Esposito V; Pecoraro A; Russo A; Vellecco V; Pepe A; Bucci M; Russo G; Galeone A
Nucleic Acids Res; 2020 Dec; 48(22):12556-12565. PubMed ID: 33270863
[TBL] [Abstract][Full Text] [Related]
7. Backbone modified TBA analogues endowed with antiproliferative activity.
Esposito V; Russo A; Amato T; Varra M; Vellecco V; Bucci M; Russo G; Virgilio A; Galeone A
Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt B):1213-1221. PubMed ID: 27663232
[TBL] [Abstract][Full Text] [Related]
8. Novel isoguanine derivative of unlocked nucleic acid-Investigations of thermodynamics and biological potential of modified thrombin binding aptamer.
Kotkowiak W; Czapik T; Pasternak A
PLoS One; 2018; 13(5):e0197835. PubMed ID: 29795635
[TBL] [Abstract][Full Text] [Related]
9. Improving the Biological Properties of Thrombin-Binding Aptamer by Incorporation of 8-Bromo-2'-Deoxyguanosine and 2'-Substituted RNA Analogues.
Virgilio A; Benigno D; Aliberti C; Vellecco V; Bucci M; Esposito V; Galeone A
Int J Mol Sci; 2023 Oct; 24(21):. PubMed ID: 37958511
[TBL] [Abstract][Full Text] [Related]
10. Investigating the role of T7 and T12 residues on the biological properties of thrombin-binding aptamer: enhancement of anticoagulant activity by a single nucleobase modification.
Borbone N; Bucci M; Oliviero G; Morelli E; Amato J; D'Atri V; D'Errico S; Vellecco V; Cirino G; Piccialli G; Fattorusso C; Varra M; Mayol L; Persico M; Scuotto M
J Med Chem; 2012 Dec; 55(23):10716-28. PubMed ID: 23126678
[TBL] [Abstract][Full Text] [Related]
11. Structural and Binding Effects of Chemical Modifications on Thrombin Binding Aptamer (TBA).
Valsangkar V; Vangaveti S; Lee GW; Fahssi WM; Awan WS; Huang Y; Chen AA; Sheng J
Molecules; 2021 Jul; 26(15):. PubMed ID: 34361773
[TBL] [Abstract][Full Text] [Related]
12. Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative.
Scuotto M; Rivieccio E; Varone A; Corda D; Bucci M; Vellecco V; Cirino G; Virgilio A; Esposito V; Galeone A; Borbone N; Varra M; Mayol L
Nucleic Acids Res; 2015 Sep; 43(16):7702-16. PubMed ID: 26250112
[TBL] [Abstract][Full Text] [Related]
13. Improving Structural Stability and Anticoagulant Activity of a Thrombin Binding Aptamer by Aromatic Modifications.
Busschaert N; Maity D; Samanta PK; English NJ; Hamilton AD
Chembiochem; 2022 Mar; 23(6):e202100670. PubMed ID: 34985829
[TBL] [Abstract][Full Text] [Related]
14. Thrombin binding aptamer analogues containing inversion of polarity sites endowed with antiproliferative and anti-motility properties against Calu-6 cells.
Esposito V; Russo A; Vellecco V; Bucci M; Russo G; Mayol L; Virgilio A; Galeone A
Biochim Biophys Acta Gen Subj; 2018 Dec; 1862(12):2645-2650. PubMed ID: 30071274
[TBL] [Abstract][Full Text] [Related]
15. Thrombin binding aptamer, more than a simple aptamer: chemically modified derivatives and biomedical applications.
Avino A; Fabrega C; Tintore M; Eritja R
Curr Pharm Des; 2012; 18(14):2036-47. PubMed ID: 22376107
[TBL] [Abstract][Full Text] [Related]
16. A mini-library of TBA analogues containing 3'-3' and 5'-5' inversion of polarity sites.
Esposito V; Galeone A; Mayol L; Randazzo A; Virgilio A; Virno A
Nucleosides Nucleotides Nucleic Acids; 2007; 26(8-9):1145-9. PubMed ID: 18058554
[TBL] [Abstract][Full Text] [Related]
17. Improved thrombin binding aptamer analogues containing inversion of polarity sites: structural effects of extra-residues at the ends.
Virgilio A; Amato T; Petraccone L; Filosa R; Varra M; Mayol L; Esposito V; Galeone A
Org Biomol Chem; 2016 Aug; 14(32):7707-14. PubMed ID: 27461474
[TBL] [Abstract][Full Text] [Related]
18. TBA loop mapping with 3'-inverted-deoxythymidine for fine-tuning of the binding affinity for α-thrombin.
Chai Z; Guo L; Jin H; Li Y; Du S; Shi Y; Wang C; Shi W; He J
Org Biomol Chem; 2019 Feb; 17(9):2403-2412. PubMed ID: 30735210
[TBL] [Abstract][Full Text] [Related]
19. Thermodynamic and biological evaluation of a thrombin binding aptamer modified with several unlocked nucleic acid (UNA) monomers and a 2'-C-piperazino-UNA monomer.
Jensen TB; Henriksen JR; Rasmussen BE; Rasmussen LM; Andresen TL; Wengel J; Pasternak A
Bioorg Med Chem; 2011 Aug; 19(16):4739-45. PubMed ID: 21795054
[TBL] [Abstract][Full Text] [Related]
20. Stability and binding properties of a modified thrombin binding aptamer.
Pagano B; Martino L; Randazzo A; Giancola C
Biophys J; 2008 Jan; 94(2):562-9. PubMed ID: 17890401
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
