BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 26586722)

  • 1. Translation Inhibition by Rocaglates Is Independent of eIF4E Phosphorylation Status.
    Chu J; Cencic R; Wang W; Porco JA; Pelletier J
    Mol Cancer Ther; 2016 Jan; 15(1):136-41. PubMed ID: 26586722
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Vesicular stomatitis virus infection alters the eIF4F translation initiation complex and causes dephosphorylation of the eIF4E binding protein 4E-BP1.
    Connor JH; Lyles DS
    J Virol; 2002 Oct; 76(20):10177-87. PubMed ID: 12239292
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ribavirin Inhibits the Activity of mTOR/eIF4E, ERK/Mnk1/eIF4E Signaling Pathway and Synergizes with Tyrosine Kinase Inhibitor Imatinib to Impair Bcr-Abl Mediated Proliferation and Apoptosis in Ph+ Leukemia.
    Shi F; Len Y; Gong Y; Shi R; Yang X; Naren D; Yan T
    PLoS One; 2015; 10(8):e0136746. PubMed ID: 26317515
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Amidino-Rocaglates: A Potent Class of eIF4A Inhibitors.
    Chu J; Zhang W; Cencic R; Devine WG; Beglov D; Henkel T; Brown LE; Vajda S; Porco JA; Pelletier J
    Cell Chem Biol; 2019 Nov; 26(11):1586-1593.e3. PubMed ID: 31519508
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cellular cap-binding protein, eIF4E, promotes picornavirus genome restructuring and translation.
    Avanzino BC; Fuchs G; Fraser CS
    Proc Natl Acad Sci U S A; 2017 Sep; 114(36):9611-9616. PubMed ID: 28827335
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F.
    Chu J; Zhang W; Cencic R; O'Connor PBF; Robert F; Devine WG; Selznick A; Henkel T; Merrick WC; Brown LE; Baranov PV; Porco JA; Pelletier J
    Cell Rep; 2020 Feb; 30(8):2481-2488.e5. PubMed ID: 32101697
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Translation initiation complex eIF4F is a therapeutic target for dual mTOR kinase inhibitors in non-Hodgkin lymphoma.
    Demosthenous C; Han JJ; Stenson MJ; Maurer MJ; Wellik LE; Link B; Hege K; Dogan A; Sotomayor E; Witzig T; Gupta M
    Oncotarget; 2015 Apr; 6(11):9488-501. PubMed ID: 25839159
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model.
    Bordeleau ME; Robert F; Gerard B; Lindqvist L; Chen SM; Wendel HG; Brem B; Greger H; Lowe SW; Porco JA; Pelletier J
    J Clin Invest; 2008 Jul; 118(7):2651-60. PubMed ID: 18551192
    [TBL] [Abstract][Full Text] [Related]  

  • 9. High affinity RNA for mammalian initiation factor 4E interferes with mRNA-cap binding and inhibits translation.
    Mochizuki K; Oguro A; Ohtsu T; Sonenberg N; Nakamura Y
    RNA; 2005 Jan; 11(1):77-89. PubMed ID: 15611299
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CRISPR-Mediated Drug-Target Validation Reveals Selective Pharmacological Inhibition of the RNA Helicase, eIF4A.
    Chu J; Galicia-Vázquez G; Cencic R; Mills JR; Katigbak A; Porco JA; Pelletier J
    Cell Rep; 2016 Jun; 15(11):2340-7. PubMed ID: 27239032
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A comparative study of small molecules targeting eIF4A.
    Naineni SK; Itoua Maïga R; Cencic R; Putnam AA; Amador LA; Rodriguez AD; Jankowsky E; Pelletier J
    RNA; 2020 May; 26(5):541-549. PubMed ID: 32014999
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation?
    Scheper GC; Proud CG
    Eur J Biochem; 2002 Nov; 269(22):5350-9. PubMed ID: 12423333
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of eukaryotic initiation factor 4E phosphorylation by cercosporamide selectively suppresses angiogenesis, growth and survival of human hepatocellular carcinoma.
    Liu Y; Sun L; Su X; Guo S
    Biomed Pharmacother; 2016 Dec; 84():237-243. PubMed ID: 27662474
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural basis for competitive inhibition of eIF4G-Mnk1 interaction by the adenovirus 100-kilodalton protein.
    Cuesta R; Xi Q; Schneider RJ
    J Virol; 2004 Jul; 78(14):7707-16. PubMed ID: 15220445
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selective targeting of the DEAD-box RNA helicase eukaryotic initiation factor (eIF) 4A by natural products.
    Shen L; Pelletier J
    Nat Prod Rep; 2020 May; 37(5):609-616. PubMed ID: 31782447
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation.
    Wang X; Yue P; Chan CB; Ye K; Ueda T; Watanabe-Fukunaga R; Fukunaga R; Fu H; Khuri FR; Sun SY
    Mol Cell Biol; 2007 Nov; 27(21):7405-13. PubMed ID: 17724079
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Monitoring flux in signalling pathways through measurements of 4EBP1-mediated eIF4F complex assembly.
    Frosi Y; Usher R; Lian DTG; Lane DP; Brown CJ
    BMC Biol; 2019 May; 17(1):40. PubMed ID: 31118010
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Requirement of the eukaryotic translation initiation factor 4F complex in hepatitis E virus replication.
    Zhou X; Xu L; Wang Y; Wang W; Sprengers D; Metselaar HJ; Peppelenbosch MP; Pan Q
    Antiviral Res; 2015 Dec; 124():11-9. PubMed ID: 26526587
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases.
    Konicek BW; Stephens JR; McNulty AM; Robichaud N; Peery RB; Dumstorf CA; Dowless MS; Iversen PW; Parsons S; Ellis KE; McCann DJ; Pelletier J; Furic L; Yingling JM; Stancato LF; Sonenberg N; Graff JR
    Cancer Res; 2011 Mar; 71(5):1849-57. PubMed ID: 21233335
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Eukaryotic initiation factor 4E (eIF4E): A recap of the cap-binding protein.
    Batool A; Aashaq S; Andrabi KI
    J Cell Biochem; 2019 Sep; 120(9):14201-14212. PubMed ID: 31074051
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.