BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

239 related articles for article (PubMed ID: 26592496)

  • 1. Immunoexpression patterns for Hypoxia-inducible Factor-1α and von Hippel-Lindau protein, in relation to Hsp90, of human brain tumors.
    Assimakopoulou M; Androutsopoulou C; Zolota V; Matsoukas J
    Histol Histopathol; 2016 May; 31(5):535-46. PubMed ID: 26592496
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ηypoxia-inducible factor-1α, von Hippel-Lindau protein, and heat shock protein expression in ophthalmic pterygium and normal conjunctiva.
    Pagoulatos D; Pharmakakis N; Lakoumentas J; Assimakopoulou M
    Mol Vis; 2014; 20():441-57. PubMed ID: 24715760
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.
    Zhou J; Schmid T; Frank R; Brüne B
    J Biol Chem; 2004 Apr; 279(14):13506-13. PubMed ID: 14726529
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.
    Osada R; Horiuchi A; Kikuchi N; Yoshida J; Hayashi A; Ota M; Katsuyama Y; Melillo G; Konishi I
    Hum Pathol; 2007 Sep; 38(9):1310-20. PubMed ID: 17555795
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Low frequency of HIF-1α overexpression in germ cell tumors of the testis.
    Vranic S; Hes O; Grossmann P; Gatalica Z
    Appl Immunohistochem Mol Morphol; 2013 Mar; 21(2):165-9. PubMed ID: 22820662
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Histone deacetylase inhibitor induced pVHL-independent degradation of HIF-1α and hierarchical quality control of pVHL via chaperone system.
    Ni J; Ni A
    PLoS One; 2021; 16(7):e0248019. PubMed ID: 34329303
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of Ran-regulated nuclear-cytoplasmic trafficking of pVHL in the regulation of microtubular stability-mediated HIF-1α in hypoxic cardiomyocytes.
    Jiang X; Zhang D; Zhang H; Huang Y; Teng M
    Sci Rep; 2015 Mar; 5():9193. PubMed ID: 25779090
    [TBL] [Abstract][Full Text] [Related]  

  • 8. COMMD1 Promotes pVHL and O2-Independent Proteolysis of HIF-1alpha via HSP90/70.
    van de Sluis B; Groot AJ; Vermeulen J; van der Wall E; van Diest PJ; Wijmenga C; Klomp LW; Vooijs M
    PLoS One; 2009 Oct; 4(10):e7332. PubMed ID: 19802386
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Degradation of HIF-1alpha under hypoxia combined with induction of Hsp90 polyubiquitination in cancer cells by hypericin: a unique cancer therapy.
    Barliya T; Mandel M; Livnat T; Weinberger D; Lavie G
    PLoS One; 2011; 6(9):e22849. PubMed ID: 21949677
    [TBL] [Abstract][Full Text] [Related]  

  • 10. von Hippel-Lindau protein adjusts oxygen sensing of the FIH asparaginyl hydroxylase.
    Li SH; Chun YS; Lim JH; Huang LE; Park JW
    Int J Biochem Cell Biol; 2011 May; 43(5):795-804. PubMed ID: 21316481
    [TBL] [Abstract][Full Text] [Related]  

  • 11. JNK1 mediates degradation HIF-1alpha by a VHL-independent mechanism that involves the chaperones Hsp90/Hsp70.
    Zhang D; Li J; Costa M; Gao J; Huang C
    Cancer Res; 2010 Jan; 70(2):813-23. PubMed ID: 20068160
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Proline hydroxylation at different sites in hypoxia-inducible factor 1α modulates its interactions with the von Hippel-Lindau tumor suppressor protein.
    Qian H; Zou Y; Tang Y; Gong Y; Qian Z; Wei G; Zhang Q
    Phys Chem Chem Phys; 2018 Jul; 20(27):18756-18765. PubMed ID: 29961792
    [TBL] [Abstract][Full Text] [Related]  

  • 13. STAT3 inhibits the degradation of HIF-1alpha by pVHL-mediated ubiquitination.
    Jung JE; Kim HS; Lee CS; Shin YJ; Kim YN; Kang GH; Kim TY; Juhnn YS; Kim SJ; Park JW; Ye SK; Chung MH
    Exp Mol Med; 2008 Oct; 40(5):479-85. PubMed ID: 18985005
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation.
    Fu C; Tyagi R; Chin AC; Rojas T; Li RJ; Guha P; Bernstein IA; Rao F; Xu R; Cha JY; Xu J; Snowman AM; Semenza GL; Snyder SH
    Circ Res; 2018 Feb; 122(3):457-472. PubMed ID: 29279301
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of point mutations in pVHL on the binding of HIF-1α.
    Domene C; Illingworth CJ
    Proteins; 2012 Mar; 80(3):733-46. PubMed ID: 22105711
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein.
    Song X; Yao J; Wang F; Zhou M; Zhou Y; Wang H; Wei L; Zhao L; Li Z; Lu N; Guo Q
    Toxicol Appl Pharmacol; 2013 Sep; 271(2):144-55. PubMed ID: 23707765
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Estrogen receptor α is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions.
    Jung YS; Lee SJ; Yoon MH; Ha NC; Park BJ
    Cell Cycle; 2012 Dec; 11(23):4462-73. PubMed ID: 23159849
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RACK1 competes with HSP90 for binding to HIF-1alpha and is required for O(2)-independent and HSP90 inhibitor-induced degradation of HIF-1alpha.
    Liu YV; Baek JH; Zhang H; Diez R; Cole RN; Semenza GL
    Mol Cell; 2007 Jan; 25(2):207-17. PubMed ID: 17244529
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hypoxia-inducible factor 1α mediates the down-regulation of superoxide dismutase 2 in von Hippel-Lindau deficient renal clear cell carcinoma.
    Gao YH; Li CX; Shen SM; Li H; Chen GQ; Wei Q; Wang LS
    Biochem Biophys Res Commun; 2013 May; 435(1):46-51. PubMed ID: 23611775
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kruppel-like factor 2 inhibits hypoxia-inducible factor 1alpha expression and function in the endothelium.
    Kawanami D; Mahabeleshwar GH; Lin Z; Atkins GB; Hamik A; Haldar SM; Maemura K; Lamanna JC; Jain MK
    J Biol Chem; 2009 Jul; 284(31):20522-30. PubMed ID: 19491109
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.