BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

230 related articles for article (PubMed ID: 26593443)

  • 1. AF4 uses the SL1 components of RNAP1 machinery to initiate MLL fusion- and AEP-dependent transcription.
    Okuda H; Kanai A; Ito S; Matsui H; Yokoyama A
    Nat Commun; 2015 Nov; 6():8869. PubMed ID: 26593443
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RNA Polymerase II-Dependent Transcription Initiated by Selectivity Factor 1: A Central Mechanism Used by MLL Fusion Proteins in Leukemic Transformation.
    Yokoyama A
    Front Genet; 2018; 9():722. PubMed ID: 30693017
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TBP loading by AF4 through SL1 is the major rate-limiting step in MLL fusion-dependent transcription.
    Okuda H; Takahashi S; Takaori-Kondo A; Yokoyama A
    Cell Cycle; 2016 Oct; 15(20):2712-22. PubMed ID: 27564129
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cooperative gene activation by AF4 and DOT1L drives MLL-rearranged leukemia.
    Okuda H; Stanojevic B; Kanai A; Kawamura T; Takahashi S; Matsui H; Takaori-Kondo A; Yokoyama A
    J Clin Invest; 2017 May; 127(5):1918-1931. PubMed ID: 28394257
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transcriptional activation by MLL fusion proteins in leukemogenesis.
    Yokoyama A
    Exp Hematol; 2017 Feb; 46():21-30. PubMed ID: 27865805
    [TBL] [Abstract][Full Text] [Related]  

  • 6. AF4 and AF4-MLL mediate transcriptional elongation of 5-lipoxygenase mRNA by 1, 25-dihydroxyvitamin D3.
    Ahmad K; Scholz B; Capelo R; Schweighöfer I; Kahnt AS; Marschalek R; Steinhilber D
    Oncotarget; 2015 Sep; 6(28):25784-800. PubMed ID: 26329759
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription.
    Yokoyama A; Lin M; Naresh A; Kitabayashi I; Cleary ML
    Cancer Cell; 2010 Feb; 17(2):198-212. PubMed ID: 20153263
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Leukemogenesis via aberrant self-renewal by the MLL/AEP-mediated transcriptional activation system.
    Yokoyama A
    Cancer Sci; 2021 Oct; 112(10):3935-3944. PubMed ID: 34251718
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Estradiol induces gene proximity and MLL-MLLT3 fusion in an activation-induced cytidine deaminase-mediated pathway.
    Wright RL; Slemmons KK; Vaughan AT
    Leuk Lymphoma; 2015 May; 56(5):1460-5. PubMed ID: 25130479
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The mixed lineage leukemia (MLL) fusion-associated gene AF4 promotes CD133 transcription.
    Mak AB; Nixon AM; Moffat J
    Cancer Res; 2012 Apr; 72(8):1929-34. PubMed ID: 22337994
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The heterodimerization domains of MLL-FYRN and FYRC--are potential target structures in t(4;11) leukemia.
    Pless B; Oehm C; Knauer S; Stauber RH; Dingermann T; Marschalek R
    Leukemia; 2011 Apr; 25(4):663-70. PubMed ID: 21233834
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis.
    Takahashi S; Kanai A; Okuda H; Miyamoto R; Komata Y; Kawamura T; Matsui H; Inaba T; Takaori-Kondo A; Yokoyama A
    Elife; 2021 Aug; 10():. PubMed ID: 34431785
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.
    Biswas D; Milne TA; Basrur V; Kim J; Elenitoba-Johnson KS; Allis CD; Roeder RG
    Proc Natl Acad Sci U S A; 2011 Sep; 108(38):15751-6. PubMed ID: 21896721
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MLL-ENL-mediated leukemia initiation at the interface of lymphoid commitment.
    Ugale A; Säwén P; Dudenhöffer-Pfeifer M; Wahlestedt M; Norddahl GL; Bryder D
    Oncogene; 2017 Jun; 36(22):3207-3212. PubMed ID: 28068328
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A carboxy-terminal domain of ELL is required and sufficient for immortalization of myeloid progenitors by MLL-ELL.
    DiMartino JF; Miller T; Ayton PM; Landewe T; Hess JL; Cleary ML; Shilatifard A
    Blood; 2000 Dec; 96(12):3887-93. PubMed ID: 11090074
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The AF4.MLL fusion protein is capable of inducing ALL in mice without requirement of MLL.AF4.
    Bursen A; Schwabe K; Rüster B; Henschler R; Ruthardt M; Dingermann T; Marschalek R
    Blood; 2010 Apr; 115(17):3570-9. PubMed ID: 20194896
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The leukemogenic AF4-MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures.
    Benedikt A; Baltruschat S; Scholz B; Bursen A; Arrey TN; Meyer B; Varagnolo L; Müller AM; Karas M; Dingermann T; Marschalek R
    Leukemia; 2011 Jan; 25(1):135-44. PubMed ID: 21030982
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular characterization of a rare MLL-AF4 (MLL-AFF1) fusion rearrangement in infant leukemia.
    Bizarro S; Cerveira N; Correia C; Lisboa S; Peixoto A; Norton L; Teixeira MR
    Cancer Genet Cytogenet; 2007 Oct; 178(1):61-4. PubMed ID: 17889710
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Keeping RNA polymerase II on the run: Functions of MLL fusion partners in transcriptional regulation.
    Basu S; Nandy A; Biswas D
    Biochim Biophys Acta Gene Regul Mech; 2020 Aug; 1863(8):194563. PubMed ID: 32348849
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crosstalk between 14-3-3θ and AF4 enhances MLL-AF4 activity and promotes leukemia cell proliferation.
    Fioretti T; Cevenini A; Zanobio M; Raia M; Sarnataro D; Salvatore F; Esposito G
    Cell Oncol (Dordr); 2019 Dec; 42(6):829-845. PubMed ID: 31493143
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.