BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 26600047)

  • 1. Mutant SOD1 Increases APP Expression and Phosphorylation in Cellular and Animal Models of ALS.
    Rabinovich-Toidman P; Rabinovich-Nikitin I; Ezra A; Barbiro B; Fogel H; Slutsky I; Solomon B
    PLoS One; 2015; 10(11):e0143420. PubMed ID: 26600047
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of amyloid precursor protein beta-secretase cleavage site affects survival and motor functions of amyotrophic lateral sclerosis transgenic mice.
    Rabinovich-Toidman P; Becker M; Barbiro B; Solomon B
    Neurodegener Dis; 2012; 10(1-4):30-3. PubMed ID: 22269310
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Brain beta-amyloid accumulation in transgenic mice expressing mutant superoxide dismutase 1.
    Turner BJ; Li QX; Laughton KM; Masters CL; Lopes EC; Atkin JD; Cheema SS
    Neurochem Res; 2004 Dec; 29(12):2281-6. PubMed ID: 15672551
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Overexpression of Abeta is associated with acceleration of onset of motor impairment and superoxide dismutase 1 aggregation in an amyotrophic lateral sclerosis mouse model.
    Li QX; Mok SS; Laughton KM; McLean CA; Volitakis I; Cherny RA; Cheung NS; White AR; Masters CL
    Aging Cell; 2006 Apr; 5(2):153-65. PubMed ID: 16626394
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Elevated levels of amyloid precursor protein in muscle of patients with amyotrophic lateral sclerosis and a mouse model of the disease.
    Koistinen H; Prinjha R; Soden P; Harper A; Banner SJ; Pradat PF; Loeffler JP; Dingwall C
    Muscle Nerve; 2006 Oct; 34(4):444-50. PubMed ID: 16856153
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Amyloid precursor protein (APP) contributes to pathology in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
    Bryson JB; Hobbs C; Parsons MJ; Bosch KD; Pandraud A; Walsh FS; Doherty P; Greensmith L
    Hum Mol Genet; 2012 Sep; 21(17):3871-82. PubMed ID: 22678056
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Gene expression profiles of APP and BACE1 in Tg SOD1G93A cortical cells.
    Spadoni O; Crestini A; Piscopo P; Malvezzi-Campeggi L; Carunchio I; Pieri M; Zona C; Confaloni A
    Cell Mol Neurobiol; 2009 Jul; 29(5):635-41. PubMed ID: 19214738
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel monoclonal antibody reveals a conformational alteration shared by amyotrophic lateral sclerosis-linked SOD1 mutants.
    Fujisawa T; Homma K; Yamaguchi N; Kadowaki H; Tsuburaya N; Naguro I; Matsuzawa A; Takeda K; Takahashi Y; Goto J; Tsuji S; Nishitoh H; Ichijo H
    Ann Neurol; 2012 Nov; 72(5):739-49. PubMed ID: 23280792
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation.
    Peviani M; Salvaneschi E; Bontempi L; Petese A; Manzo A; Rossi D; Salmona M; Collina S; Bigini P; Curti D
    Neurobiol Dis; 2014 Feb; 62():218-32. PubMed ID: 24141020
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Trehalose decreases mutant SOD1 expression and alleviates motor deficiency in early but not end-stage amyotrophic lateral sclerosis in a SOD1-G93A mouse model.
    Li Y; Guo Y; Wang X; Yu X; Duan W; Hong K; Wang J; Han H; Li C
    Neuroscience; 2015 Jul; 298():12-25. PubMed ID: 25841320
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of STAT3 and inhibitory effects of pioglitazone on STAT3 activity in a mouse model of SOD1-mutated amyotrophic lateral sclerosis.
    Shibata N; Yamamoto T; Hiroi A; Omi Y; Kato Y; Kobayashi M
    Neuropathology; 2010 Aug; 30(4):353-60. PubMed ID: 19925559
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Immunodetection of disease-associated conformers of mutant cu/zn superoxide dismutase 1 selectively expressed in degenerating neurons in amyotrophic lateral sclerosis.
    Sábado J; Casanovas A; Hernández S; Piedrafita L; Hereu M; Esquerda JE
    J Neuropathol Exp Neurol; 2013 Jul; 72(7):646-61. PubMed ID: 23771221
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy.
    Turner BJ; Bäumer D; Parkinson NJ; Scaber J; Ansorge O; Talbot K
    BMC Neurosci; 2008 Oct; 9():104. PubMed ID: 18957104
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A cysteine residue affects the conformational state and neuronal toxicity of mutant SOD1 in mice: relevance to the pathogenesis of ALS.
    Nagano S; Takahashi Y; Yamamoto K; Masutani H; Fujiwara N; Urushitani M; Araki T
    Hum Mol Genet; 2015 Jun; 24(12):3427-39. PubMed ID: 25762155
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Aberrant association of misfolded SOD1 with Na(+)/K(+)ATPase-α3 impairs its activity and contributes to motor neuron vulnerability in ALS.
    Ruegsegger C; Maharjan N; Goswami A; Filézac de L'Etang A; Weis J; Troost D; Heller M; Gut H; Saxena S
    Acta Neuropathol; 2016 Mar; 131(3):427-51. PubMed ID: 26619836
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overexpression of metallothionein-I, a copper-regulating protein, attenuates intracellular copper dyshomeostasis and extends lifespan in a mouse model of amyotrophic lateral sclerosis caused by mutant superoxide dismutase-1.
    Tokuda E; Okawa E; Watanabe S; Ono S
    Hum Mol Genet; 2014 Mar; 23(5):1271-85. PubMed ID: 24163136
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neuron-specific overexpression of the co-chaperone Bcl-2-associated athanogene-1 in superoxide dismutase 1(G93A)-transgenic mice.
    Rohde G; Kermer P; Reed JC; Bähr M; Weishaupt JH
    Neuroscience; 2008 Dec; 157(4):844-9. PubMed ID: 18955116
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Over-expression of Hsp27 does not influence disease in the mutant SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
    Krishnan J; Vannuvel K; Andries M; Waelkens E; Robberecht W; Van Den Bosch L
    J Neurochem; 2008 Sep; 106(5):2170-83. PubMed ID: 18624915
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Postsynaptic alteration of NR2A subunit and defective autophosphorylation of alphaCaMKII at threonine-286 contribute to abnormal plasticity and morphology of upper motor neurons in presymptomatic SOD1G93A mice, a murine model for amyotrophic lateral sclerosis.
    Spalloni A; Origlia N; Sgobio C; Trabalza A; Nutini M; Berretta N; Bernardi G; Domenici L; Ammassari-Teule M; Longone P
    Cereb Cortex; 2011 Apr; 21(4):796-805. PubMed ID: 20732897
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.