274 related articles for article (PubMed ID: 26603102)
1. Neuronal gene repression in Niemann-Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway.
Contreras PS; Gonzalez-Zuñiga M; González-Hódar L; Yáñez MJ; Dulcey A; Marugan J; Seto E; Alvarez AR; Zanlungo S
Biochim Biophys Acta; 2016 Feb; 1859(2):269-79. PubMed ID: 26603102
[TBL] [Abstract][Full Text] [Related]
2. Vitamin E dietary supplementation improves neurological symptoms and decreases c-Abl/p73 activation in Niemann-Pick C mice.
Marín T; Contreras P; Castro JF; Chamorro D; Balboa E; Bosch-Morató M; Muñoz FJ; Alvarez AR; Zanlungo S
Nutrients; 2014 Jul; 6(8):3000-17. PubMed ID: 25079853
[TBL] [Abstract][Full Text] [Related]
3. c-Abl stabilizes HDAC2 levels by tyrosine phosphorylation repressing neuronal gene expression in Alzheimer's disease.
Gonzalez-Zuñiga M; Contreras PS; Estrada LD; Chamorro D; Villagra A; Zanlungo S; Seto E; Alvarez AR
Mol Cell; 2014 Oct; 56(1):163-73. PubMed ID: 25219501
[TBL] [Abstract][Full Text] [Related]
4. Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann-Pick type C disease.
Alvarez AR; Klein A; Castro J; Cancino GI; Amigo J; Mosqueira M; Vargas LM; Yévenes LF; Bronfman FC; Zanlungo S
FASEB J; 2008 Oct; 22(10):3617-27. PubMed ID: 18591368
[TBL] [Abstract][Full Text] [Related]
5. Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons.
Klein A; Maldonado C; Vargas LM; Gonzalez M; Robledo F; Perez de Arce K; Muñoz FJ; Hetz C; Alvarez AR; Zanlungo S
Neurobiol Dis; 2011 Jan; 41(1):209-18. PubMed ID: 20883783
[TBL] [Abstract][Full Text] [Related]
6. Normalization of Hepatic Homeostasis in the
Munkacsi AB; Hammond N; Schneider RT; Senanayake DS; Higaki K; Lagutin K; Bloor SJ; Ory DS; Maue RA; Chen FW; Hernandez-Ono A; Dahlson N; Repa JJ; Ginsberg HN; Ioannou YA; Sturley SL
J Biol Chem; 2017 Mar; 292(11):4395-4410. PubMed ID: 28031458
[TBL] [Abstract][Full Text] [Related]
7. High-content screen for modifiers of Niemann-Pick type C disease in patient cells.
Pugach EK; Feltes M; Kaufman RJ; Ory DS; Bang AG
Hum Mol Genet; 2018 Jun; 27(12):2101-2112. PubMed ID: 29659804
[TBL] [Abstract][Full Text] [Related]
8. Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression.
Davidson CD; Ali NF; Micsenyi MC; Stephney G; Renault S; Dobrenis K; Ory DS; Vanier MT; Walkley SU
PLoS One; 2009 Sep; 4(9):e6951. PubMed ID: 19750228
[TBL] [Abstract][Full Text] [Related]
9. Lysosomal vitamin E accumulation in Niemann-Pick type C disease.
Yévenes LF; Klein A; Castro JF; Marín T; Leal N; Leighton F; Alvarez AR; Zanlungo S
Biochim Biophys Acta; 2012 Feb; 1822(2):150-60. PubMed ID: 22120593
[TBL] [Abstract][Full Text] [Related]
10. Treatment of Niemann--pick type C disease by histone deacetylase inhibitors.
Helquist P; Maxfield FR; Wiech NL; Wiest O
Neurotherapeutics; 2013 Oct; 10(4):688-97. PubMed ID: 24048860
[TBL] [Abstract][Full Text] [Related]
11. Niemann-Pick Disease Type C: from molecule to clinic.
Tang Y; Li H; Liu JP
Clin Exp Pharmacol Physiol; 2010 Jan; 37(1):132-40. PubMed ID: 19566836
[TBL] [Abstract][Full Text] [Related]
12. Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts.
Pipalia NH; Cosner CC; Huang A; Chatterjee A; Bourbon P; Farley N; Helquist P; Wiest O; Maxfield FR
Proc Natl Acad Sci U S A; 2011 Apr; 108(14):5620-5. PubMed ID: 21436030
[TBL] [Abstract][Full Text] [Related]
13. Mutant human APP exacerbates pathology in a mouse model of NPC and its reversal by a β-cyclodextrin.
Maulik M; Ghoshal B; Kim J; Wang Y; Yang J; Westaway D; Kar S
Hum Mol Genet; 2012 Nov; 21(22):4857-75. PubMed ID: 22869680
[TBL] [Abstract][Full Text] [Related]
14. Niemann-Pick Disease Type C: Induced Pluripotent Stem Cell-Derived Neuronal Cells for Modeling Neural Disease and Evaluating Drug Efficacy.
Yu D; Swaroop M; Wang M; Baxa U; Yang R; Yan Y; Coksaygan T; DeTolla L; Marugan JJ; Austin CP; McKew JC; Gong DW; Zheng W
J Biomol Screen; 2014 Sep; 19(8):1164-73. PubMed ID: 24907126
[TBL] [Abstract][Full Text] [Related]
15. c-Abl links APP-BACE1 interaction promoting APP amyloidogenic processing in Niemann-Pick type C disease.
Yáñez MJ; Belbin O; Estrada LD; Leal N; Contreras PS; Lleó A; Burgos PV; Zanlungo S; Alvarez AR
Biochim Biophys Acta; 2016 Nov; 1862(11):2158-2167. PubMed ID: 27565738
[TBL] [Abstract][Full Text] [Related]
16. Polyrotaxane-based systemic delivery of β-cyclodextrins for potentiating therapeutic efficacy in a mouse model of Niemann-Pick type C disease.
Tamura A; Yui N
J Control Release; 2018 Jan; 269():148-158. PubMed ID: 29138063
[TBL] [Abstract][Full Text] [Related]
17. 2-Hydroxypropyl-gamma-cyclodextrin overcomes NPC1 deficiency by enhancing lysosome-ER association and autophagy.
Singhal A; Krystofiak ES; Jerome WG; Song B
Sci Rep; 2020 May; 10(1):8663. PubMed ID: 32457374
[TBL] [Abstract][Full Text] [Related]
18. Investigation of 2-Hydroxypropyl-β-Cyclodextrin Treatment in a Neuronal-Like Cell Model of Niemann-Pick Type C Using Quantitative Proteomics.
Cougnoux A; Pergande MR; Serna-Perez F; Cologna SM
J Am Soc Mass Spectrom; 2023 Apr; 34(4):668-675. PubMed ID: 36920149
[TBL] [Abstract][Full Text] [Related]
19. Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK.
Dai S; Dulcey AE; Hu X; Wassif CA; Porter FD; Austin CP; Ory DS; Marugan J; Zheng W
Autophagy; 2017 Aug; 13(8):1435-1451. PubMed ID: 28613987
[TBL] [Abstract][Full Text] [Related]
20. Human iNSC-derived brain organoid model of lysosomal storage disorder in Niemann-Pick disease type C.
Lee SE; Shin N; Kook MG; Kong D; Kim NG; Choi SW; Kang KS
Cell Death Dis; 2020 Dec; 11(12):1059. PubMed ID: 33311479
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]