BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

377 related articles for article (PubMed ID: 26603896)

  • 1. DNA-PKcs and PARP1 Bind to Unresected Stalled DNA Replication Forks Where They Recruit XRCC1 to Mediate Repair.
    Ying S; Chen Z; Medhurst AL; Neal JA; Bao Z; Mortusewicz O; McGouran J; Song X; Shen H; Hamdy FC; Kessler BM; Meek K; Helleday T
    Cancer Res; 2016 Mar; 76(5):1078-88. PubMed ID: 26603896
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination.
    Bryant HE; Petermann E; Schultz N; Jemth AS; Loseva O; Issaeva N; Johansson F; Fernandez S; McGlynn P; Helleday T
    EMBO J; 2009 Sep; 28(17):2601-15. PubMed ID: 19629035
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mre11-dependent degradation of stalled DNA replication forks is prevented by BRCA2 and PARP1.
    Ying S; Hamdy FC; Helleday T
    Cancer Res; 2012 Jun; 72(11):2814-21. PubMed ID: 22447567
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stalled replication forks within heterochromatin require ATRX for protection.
    Huh MS; Ivanochko D; Hashem LE; Curtin M; Delorme M; Goodall E; Yan K; Picketts DJ
    Cell Death Dis; 2016 May; 7(5):e2220. PubMed ID: 27171262
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cockayne syndrome group B protein regulates fork restart, fork progression and MRE11-dependent fork degradation in BRCA1/2-deficient cells.
    Batenburg NL; Mersaoui SY; Walker JR; Coulombe Y; Hammond-Martel I; Wurtele H; Masson JY; Zhu XD
    Nucleic Acids Res; 2021 Dec; 49(22):12836-12854. PubMed ID: 34871413
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.
    Petermann E; Orta ML; Issaeva N; Schultz N; Helleday T
    Mol Cell; 2010 Feb; 37(4):492-502. PubMed ID: 20188668
    [TBL] [Abstract][Full Text] [Related]  

  • 7. XRCC1 interacts with the p58 subunit of DNA Pol alpha-primase and may coordinate DNA repair and replication during S phase.
    Lévy N; Oehlmann M; Delalande F; Nasheuer HP; Van Dorsselaer A; Schreiber V; de Murcia G; Ménissier-de Murcia J; Maiorano D; Bresson A
    Nucleic Acids Res; 2009 Jun; 37(10):3177-88. PubMed ID: 19305001
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair.
    Bryant HE; Helleday T
    Nucleic Acids Res; 2006; 34(6):1685-91. PubMed ID: 16556909
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PIDD mediates the association of DNA-PKcs and ATR at stalled replication forks to facilitate the ATR signaling pathway.
    Lin YF; Shih HY; Shang ZF; Kuo CT; Guo J; Du C; Lee H; Chen BPC
    Nucleic Acids Res; 2018 Feb; 46(4):1847-1859. PubMed ID: 29309644
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The oncoprotein DEK affects the outcome of PARP1/2 inhibition during mild replication stress.
    Ganz M; Vogel C; Czada C; Jörke V; Gwosch EC; Kleiner R; Pierzynska-Mach A; Zanacchi FC; Diaspro A; Kappes F; Bürkle A; Ferrando-May E
    PLoS One; 2019; 14(8):e0213130. PubMed ID: 31408463
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks.
    Yang YG; Cortes U; Patnaik S; Jasin M; Wang ZQ
    Oncogene; 2004 May; 23(21):3872-82. PubMed ID: 15021907
    [TBL] [Abstract][Full Text] [Related]  

  • 12. APLF facilitates interstrand DNA crosslink repair and replication fork protection to confer cisplatin resistance.
    Wu CK; Shiu JL; Wu CL; Hung CF; Ho YC; Chen YT; Tung SY; Yeh CF; Shen CH; Liaw H; Su WP
    Nucleic Acids Res; 2024 Jun; 52(10):5676-5697. PubMed ID: 38520407
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks.
    Bolderson E; Petermann E; Croft L; Suraweera A; Pandita RK; Pandita TK; Helleday T; Khanna KK; Richard DJ
    Nucleic Acids Res; 2014 Jun; 42(10):6326-36. PubMed ID: 24753408
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells.
    Kim JJ; Lee SY; Choi JH; Woo HG; Xhemalce B; Miller KM
    Mol Cell; 2020 Oct; 80(2):327-344.e8. PubMed ID: 32966758
    [TBL] [Abstract][Full Text] [Related]  

  • 15. XRCC1 promotes replication restart, nascent fork degradation and mutagenic DNA repair in BRCA2-deficient cells.
    Eckelmann BJ; Bacolla A; Wang H; Ye Z; Guerrero EN; Jiang W; El-Zein R; Hegde ML; Tomkinson AE; Tainer JA; Mitra S
    NAR Cancer; 2020 Sep; 2(3):zcaa013. PubMed ID: 32776008
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Involvement of the Artemis protein in the relative biological efficiency observed with the 76-MeV proton beam used at the Institut Curie Proton Therapy Center in Orsay.
    Calugaru V; Nauraye C; Cordelières FP; Biard D; De Marzi L; Hall J; Favaudon V; Mégnin-Chanet F
    Int J Radiat Oncol Biol Phys; 2014 Sep; 90(1):36-43. PubMed ID: 25195988
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart.
    Somyajit K; Saxena S; Babu S; Mishra A; Nagaraju G
    Nucleic Acids Res; 2015 Nov; 43(20):9835-55. PubMed ID: 26354865
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent-strand DNA.
    Lyu X; Lei KH; Biak Sang P; Shiva O; Chastain M; Chi P; Chai W
    EMBO J; 2021 Jan; 40(2):e103654. PubMed ID: 33210317
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Visualization of a DNA-PK/PARP1 complex.
    Spagnolo L; Barbeau J; Curtin NJ; Morris EP; Pearl LH
    Nucleic Acids Res; 2012 May; 40(9):4168-77. PubMed ID: 22223246
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Poly(ADP-Ribose) polymerase-1 and DNA-dependent protein kinase have equivalent roles in double strand break repair following ionizing radiation.
    Mitchell J; Smith GC; Curtin NJ
    Int J Radiat Oncol Biol Phys; 2009 Dec; 75(5):1520-7. PubMed ID: 19931734
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.