126 related articles for article (PubMed ID: 26609109)
1. Hypermutation of DPYD Deregulates Pyrimidine Metabolism and Promotes Malignant Progression.
Edwards L; Gupta R; Filipp FV
Mol Cancer Res; 2016 Feb; 14(2):196-206. PubMed ID: 26609109
[TBL] [Abstract][Full Text] [Related]
2. P53 represses pyrimidine catabolic gene dihydropyrimidine dehydrogenase (DPYD) expression in response to thymidylate synthase (TS) targeting.
Gokare P; Finnberg NK; Abbosh PH; Dai J; Murphy ME; El-Deiry WS
Sci Rep; 2017 Aug; 7(1):9711. PubMed ID: 28851987
[TBL] [Abstract][Full Text] [Related]
3. Cancer systems biology of TCGA SKCM: efficient detection of genomic drivers in melanoma.
Guan J; Gupta R; Filipp FV
Sci Rep; 2015 Jan; 5():7857. PubMed ID: 25600636
[TBL] [Abstract][Full Text] [Related]
4. Two cases of 5-fluorouracil toxicity linked with gene variants in the DPYD gene.
Ofverholm A; Arkblad E; Skrtic S; Albertsson P; Shubbar E; Enerbäck C
Clin Biochem; 2010 Feb; 43(3):331-4. PubMed ID: 19822137
[TBL] [Abstract][Full Text] [Related]
5. Analysis of pyrimidine catabolism in Drosophila melanogaster using epistatic interactions with mutations of pyrimidine biosynthesis and beta-alanine metabolism.
Rawls JM
Genetics; 2006 Mar; 172(3):1665-74. PubMed ID: 16361227
[TBL] [Abstract][Full Text] [Related]
6. Lack of large intragenic rearrangements in dihydropyrimidine dehydrogenase (DPYD) gene in fluoropyrimidine-treated patients with high-grade toxicity.
Ticha I; Kleiblova P; Fidlerova J; Novotny J; Pohlreich P; Kleibl Z
Cancer Chemother Pharmacol; 2009 Aug; 64(3):615-8. PubMed ID: 19288105
[TBL] [Abstract][Full Text] [Related]
7. Mutational analysis of the human dihydropyrimidine dehydrogenase gene by denaturing high-performance liquid chromatography.
Fischer J; Schwab M; Eichelbaum M; Zanger UM
Genet Test; 2003; 7(2):97-105. PubMed ID: 12885330
[TBL] [Abstract][Full Text] [Related]
8. Dihydropyrimidine dehydrogenase deficiency caused by a novel genomic deletion c.505_513del of DPYD.
van Kuilenburg AB; Meijer J; Gökcay G; Baykal T; Rubio-Gozalbo ME; Mul AN; de Die-Smulders CE; Weber P; Mori AC; Bierau J; Fowler B; Macke K; Sass JO; Meinsma R; Hennermann JB; Miny P; Zoetekouw L; Roelofsen J; Vijzelaar R; Nicolai J; Hennekam RC
Nucleosides Nucleotides Nucleic Acids; 2010 Jun; 29(4-6):509-14. PubMed ID: 20544545
[TBL] [Abstract][Full Text] [Related]
9. Identification of two novel mutations C79X and R235Q in the dihydropyrimidine dehydrogenase gene in a patient presenting with hematuria.
van Kuilenburg AB; Meijer J; Dobritzsch D; Lohkamp B; Ruitenbeek W; Roelofsen J; Abeling NG; Duran M; Buzing C
Nucleosides Nucleotides Nucleic Acids; 2008 Jun; 27(6):809-15. PubMed ID: 18600544
[TBL] [Abstract][Full Text] [Related]
10. FRA1E common fragile site breaks map within a 370kilobase pair region and disrupt the dihydropyrimidine dehydrogenase gene (DPYD).
Hormozian F; Schmitt JG; Sagulenko E; Schwab M; Savelyeva L
Cancer Lett; 2007 Feb; 246(1-2):82-91. PubMed ID: 16556484
[TBL] [Abstract][Full Text] [Related]
11. Dihydropyrimidine dehydrogenase pharmacogenetics in the Taiwanese population.
Hsiao HH; Yang MY; Chang JG; Liu YC; Liu TC; Chang CS; Chen TP; Lin SF
Cancer Chemother Pharmacol; 2004 May; 53(5):445-51. PubMed ID: 15132136
[TBL] [Abstract][Full Text] [Related]
12. Translating DPYD genotype into DPD phenotype: using the DPYD gene activity score.
Henricks LM; Lunenburg CA; Meulendijks D; Gelderblom H; Cats A; Swen JJ; Schellens JH; Guchelaar HJ
Pharmacogenomics; 2015; 16(11):1277-86. PubMed ID: 26265346
[TBL] [Abstract][Full Text] [Related]
13. Hypermethylation of the DPYD promoter region is not a major predictor of severe toxicity in 5-fluorouracil based chemotherapy.
Amstutz U; Farese S; Aebi S; Largiadèr CR
J Exp Clin Cancer Res; 2008 Oct; 27(1):54. PubMed ID: 18937829
[TBL] [Abstract][Full Text] [Related]
14. Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk.
Kelemen LE; Terry KL; Goodman MT; Webb PM; Bandera EV; McGuire V; Rossing MA; Wang Q; Dicks E; Tyrer JP; Song H; Kupryjanczyk J; Dansonka-Mieszkowska A; Plisiecka-Halasa J; Timorek A; Menon U; Gentry-Maharaj A; Gayther SA; Ramus SJ; Narod SA; Risch HA; McLaughlin JR; Siddiqui N; Glasspool R; Paul J; Carty K; Gronwald J; Lubiński J; Jakubowska A; Cybulski C; Kiemeney LA; Massuger LF; van Altena AM; Aben KK; Olson SH; Orlow I; Cramer DW; Levine DA; Bisogna M; Giles GG; Southey MC; Bruinsma F; Kjaer SK; Høgdall E; Jensen A; Høgdall CK; Lundvall L; Engelholm SA; Heitz F; du Bois A; Harter P; Schwaab I; Butzow R; Nevanlinna H; Pelttari LM; Leminen A; Thompson PJ; Lurie G; Wilkens LR; Lambrechts D; Van Nieuwenhuysen E; Lambrechts S; Vergote I; Beesley J; ; Fasching PA; Beckmann MW; Hein A; Ekici AB; Doherty JA; Wu AH; Pearce CL; Pike MC; Stram D; Chang-Claude J; Rudolph A; Dörk T; Dürst M; Hillemanns P; Runnebaum IB; Bogdanova N; Antonenkova N; Odunsi K; Edwards RP; Kelley JL; Modugno F; Ness RB; Karlan BY; Walsh C; Lester J; Orsulic S; Fridley BL; Vierkant RA; Cunningham JM; Wu X; Lu K; Liang D; Hildebrandt MA; Weber RP; Iversen ES; Tworoger SS; Poole EM; Salvesen HB; Krakstad C; Bjorge L; Tangen IL; Pejovic T; Bean Y; Kellar M; Wentzensen N; Brinton LA; Lissowska J; Garcia-Closas M; Campbell IG; Eccles D; Whittemore AS; Sieh W; Rothstein JH; Anton-Culver H; Ziogas A; Phelan CM; Moysich KB; Goode EL; Schildkraut JM; Berchuck A; Pharoah PD; Sellers TA; Brooks-Wilson A; Cook LS; Le ND
Mol Nutr Food Res; 2014 Oct; 58(10):2023-35. PubMed ID: 25066213
[TBL] [Abstract][Full Text] [Related]
15. Mutational spectrum of dihydropyrimidine dehydrogenase gene (DPYD) in the Tunisian population.
Ben Fredj R; Gross E; Chouchen L; B'Chir F; Ben Ahmed S; Neubauer S; Kiechle M; Saguem S
C R Biol; 2007 Oct; 330(10):764-9. PubMed ID: 17905396
[TBL] [Abstract][Full Text] [Related]
16. Pseudomonas putida PydR, a RutR-like transcriptional regulator, represses the dihydropyrimidine dehydrogenase gene in the pyrimidine reductive catabolic pathway.
Hidese R; Mihara H; Kurihara T; Esaki N
J Biochem; 2012 Oct; 152(4):341-6. PubMed ID: 22782928
[TBL] [Abstract][Full Text] [Related]
17. Methylation of the DPYD promoter: an alternative mechanism for dihydropyrimidine dehydrogenase deficiency in cancer patients.
Ezzeldin HH; Lee AM; Mattison LK; Diasio RB
Clin Cancer Res; 2005 Dec; 11(24 Pt 1):8699-705. PubMed ID: 16361556
[TBL] [Abstract][Full Text] [Related]
18. Hemizygous deletions on chromosome 1p21.3 involving the DPYD gene in individuals with autism spectrum disorder.
Carter MT; Nikkel SM; Fernandez BA; Marshall CR; Noor A; Lionel AC; Prasad A; Pinto D; Joseph-George AM; Noakes C; Fairbrother-Davies C; Roberts W; Vincent J; Weksberg R; Scherer SW
Clin Genet; 2011 Nov; 80(5):435-43. PubMed ID: 21114665
[TBL] [Abstract][Full Text] [Related]
19. Dihydropyrimidine dehydrogenase: a flavoprotein with four iron-sulfur clusters.
Schnackerz KD; Dobritzsch D; Lindqvist Y; Cook PF
Biochim Biophys Acta; 2004 Sep; 1701(1-2):61-74. PubMed ID: 15450176
[TBL] [Abstract][Full Text] [Related]
20. Activator protein accelerates dihydropyrimidine dehydrogenase gene transcription in cancer cells.
Ukon K; Tanimoto K; Shimokuni T; Noguchi T; Hiyama K; Tsujimoto H; Fukushima M; Toge T; Nishiyama M
Cancer Res; 2005 Feb; 65(3):1055-62. PubMed ID: 15705907
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
