190 related articles for article (PubMed ID: 26612036)
1. Conservation and Role of Electrostatics in Thymidylate Synthase.
Garg D; Skouloubris S; Briffotaux J; Myllykallio H; Wade RC
Sci Rep; 2015 Nov; 5():17356. PubMed ID: 26612036
[TBL] [Abstract][Full Text] [Related]
2. The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261.
Newby Z; Lee TT; Morse RJ; Liu Y; Liu L; Venkatraman P; Santi DV; Finer-Moore JS; Stroud RM
Biochemistry; 2006 Jun; 45(24):7415-28. PubMed ID: 16768437
[TBL] [Abstract][Full Text] [Related]
3. Crystal structures of thymidylate synthase mutant R166Q: structural basis for the nearly complete loss of catalytic activity.
Sotelo-Mundo RR; Changchien L; Maley F; Montfort WR
J Biochem Mol Toxicol; 2006; 20(2):88-92. PubMed ID: 16615077
[TBL] [Abstract][Full Text] [Related]
4. An essential role for water in an enzyme reaction mechanism: the crystal structure of the thymidylate synthase mutant E58Q.
Sage CR; Rutenber EE; Stout TJ; Stroud RM
Biochemistry; 1996 Dec; 35(50):16270-81. PubMed ID: 8973201
[TBL] [Abstract][Full Text] [Related]
5. The additivity of substrate fragments in enzyme-ligand binding.
Stout TJ; Sage CR; Stroud RM
Structure; 1998 Jul; 6(7):839-48. PubMed ID: 9687366
[TBL] [Abstract][Full Text] [Related]
6. Chemical shift imprint of intersubunit communication in a symmetric homodimer.
Falk BT; Sapienza PJ; Lee AL
Proc Natl Acad Sci U S A; 2016 Aug; 113(34):9533-8. PubMed ID: 27466406
[TBL] [Abstract][Full Text] [Related]
7. Kinetic scheme for thymidylate synthase from Escherichia coli: determination from measurements of ligand binding, primary and secondary isotope effects, and pre-steady-state catalysis.
Spencer HT; Villafranca JE; Appleman JR
Biochemistry; 1997 Apr; 36(14):4212-22. PubMed ID: 9100016
[TBL] [Abstract][Full Text] [Related]
8. Structural basis for recognition of polyglutamyl folates by thymidylate synthase.
Kamb A; Finer-Moore J; Calvert AH; Stroud RM
Biochemistry; 1992 Oct; 31(41):9883-90. PubMed ID: 1390771
[TBL] [Abstract][Full Text] [Related]
9. Catalytic mechanism of Chlamydia trachomatis flavin-dependent thymidylate synthase.
Griffin J; Roshick C; Iliffe-Lee E; McClarty G
J Biol Chem; 2005 Feb; 280(7):5456-67. PubMed ID: 15591067
[TBL] [Abstract][Full Text] [Related]
10. Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP.
Almog R; Waddling CA; Maley F; Maley GF; Van Roey P
Protein Sci; 2001 May; 10(5):988-96. PubMed ID: 11316879
[TBL] [Abstract][Full Text] [Related]
11. Pairwise specificity and sequential binding in enzyme catalysis: thymidylate synthase.
Finer-Moore JS; Montfort WR; Stroud RM
Biochemistry; 1990 Jul; 29(30):6977-86. PubMed ID: 2223755
[TBL] [Abstract][Full Text] [Related]
12. Subunit complementation of thymidylate synthase in Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase.
Chanama M; Chitnumsub P; Yuthavong Y
Mol Biochem Parasitol; 2005 Jan; 139(1):83-90. PubMed ID: 15610822
[TBL] [Abstract][Full Text] [Related]
13. The crystal structure of thymidylate synthase from Pneumocystis carinii reveals a fungal insert important for drug design.
Anderson AC; Perry KM; Freymann DM; Stroud RM
J Mol Biol; 2000 Mar; 297(3):645-57. PubMed ID: 10731418
[TBL] [Abstract][Full Text] [Related]
14. Partitioning roles of side chains in affinity, orientation, and catalysis with structures for mutant complexes: asparagine-229 in thymidylate synthase.
Finer-Moore JS; Liu L; Schafmeister CE; Birdsall DL; Mau T; Santi DV; Stroud RM
Biochemistry; 1996 Apr; 35(16):5125-36. PubMed ID: 8611496
[TBL] [Abstract][Full Text] [Related]
15. Cofactor triggers the conformational change in thymidylate synthase: implications for an ordered binding mechanism.
Kamb A; Finer-Moore JS; Stroud RM
Biochemistry; 1992 Dec; 31(51):12876-84. PubMed ID: 1281428
[TBL] [Abstract][Full Text] [Related]
16. Properties of bacteriophage T4 thymidylate synthase following mutagenic changes in the active site and folate binding region.
LaPat-Polasko L; Maley GF; Maley F
Biochemistry; 1990 Oct; 29(41):9561-72. PubMed ID: 2271601
[TBL] [Abstract][Full Text] [Related]
17. The complex of the anti-cancer therapeutic, BW1843U89, with thymidylate synthase at 2.0 A resolution: implications for a new mode of inhibition.
Stout TJ; Stroud RM
Structure; 1996 Jan; 4(1):67-77. PubMed ID: 8805515
[TBL] [Abstract][Full Text] [Related]
18. Multi-targeted antifolates aimed at avoiding drug resistance form covalent closed inhibitory complexes with human and Escherichia coli thymidylate synthases.
Sayre PH; Finer-Moore JS; Fritz TA; Biermann D; Gates SB; MacKellar WC; Patel VF; Stroud RM
J Mol Biol; 2001 Nov; 313(4):813-29. PubMed ID: 11697906
[TBL] [Abstract][Full Text] [Related]
19. Structure, multiple site binding, and segmental accommodation in thymidylate synthase on binding dUMP and an anti-folate.
Montfort WR; Perry KM; Fauman EB; Finer-Moore JS; Maley GF; Hardy L; Maley F; Stroud RM
Biochemistry; 1990 Jul; 29(30):6964-77. PubMed ID: 2223754
[TBL] [Abstract][Full Text] [Related]
20. Functional identity of the active sites of crustacean and viral thymidylate synthases.
Arvizu-Flores AA; Aispuro-Hernandez E; Garcia-Orozco KD; Varela-Romero A; Valenzuela-Soto E; Velazquez-Contreras EF; Rojo-DomÃnguez A; Yepiz-Plascencia G; Maley F; Sotelo-Mundo RR
Comp Biochem Physiol C Toxicol Pharmacol; 2009 Sep; 150(3):406-13. PubMed ID: 19559812
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
