BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

71 related articles for article (PubMed ID: 26621242)

  • 1. Homology Models and Molecular Modeling of Human Retinoic Acid Metabolizing Enzymes Cytochrome P450 26A1 (CYP26A1) and P450 26B1 (CYP26B1).
    Karlsson M; Strid Å; Sirsjö A; Eriksson LA
    J Chem Theory Comput; 2008 Jun; 4(6):1021-7. PubMed ID: 26621242
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Homology model of human retinoic acid metabolising enzyme cytochrome P450 26A1 (CYP26A1): active site architecture and ligand binding.
    Gomaa MS; Yee SW; Milbourne CE; Barbera MC; Simons C; Brancale A
    J Enzyme Inhib Med Chem; 2006 Aug; 21(4):361-9. PubMed ID: 17059167
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Homology models of human all-trans retinoic acid metabolizing enzymes CYP26B1 and CYP26B1 spliced variant.
    Saenz-Méndez P; Elmabsout AA; Sävenstrand H; Awadalla MK; Strid Å; Sirsjö A; Eriksson LA
    J Chem Inf Model; 2012 Oct; 52(10):2631-7. PubMed ID: 22985482
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular recognition of CYP26A1 binding pockets and structure-activity relationship studies for design of potent and selective retinoic acid metabolism blocking agents.
    Sun B; Song S; Hao CZ; Huang WX; Liu CC; Xie HL; Lin B; Cheng MS; Zhao DM
    J Mol Graph Model; 2015 Mar; 56():10-9. PubMed ID: 25541526
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of Tazarotenic Acid as the First Xenobiotic Substrate of Human Retinoic Acid Hydroxylase CYP26A1 and CYP26B1.
    Foti RS; Isoherranen N; Zelter A; Dickmann LJ; Buttrick BR; Diaz P; Douguet D
    J Pharmacol Exp Ther; 2016 May; 357(2):281-92. PubMed ID: 26937021
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Improved Homology Model of the Human all-trans Retinoic Acid Metabolizing Enzyme CYP26A1.
    Awadalla MK; Alshammari TM; Eriksson LA; Saenz-Méndez P
    Molecules; 2016 Mar; 21(3):351. PubMed ID: 26999080
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of NADPH-cytochrome P450 reductase on all-trans-retinoic acid efficacy and cytochrome P450 26A1 expression in human myeloid leukaemia HL-60 cells.
    Hu L; Lv JF; Zhuo W; Zhang CM; Zhou HH; Fan L
    J Pharm Pharmacol; 2016 Sep; 68(9):1193-202. PubMed ID: 27366899
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comparison of the function and expression of CYP26A1 and CYP26B1, the two retinoic acid hydroxylases.
    Topletz AR; Thatcher JE; Zelter A; Lutz JD; Tay S; Nelson WL; Isoherranen N
    Biochem Pharmacol; 2012 Jan; 83(1):149-63. PubMed ID: 22020119
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparison of the ligand binding site of CYP2C8 with CYP26A1 and CYP26B1: a structural basis for the identification of new inhibitors of the retinoic acid hydroxylases.
    Foti RS; Diaz P; Douguet D
    J Enzyme Inhib Med Chem; 2016; 31(sup2):148-161. PubMed ID: 27424662
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CRABPs Alter
    Yabut KCB; Isoherranen N
    Nutrients; 2022 Apr; 14(9):. PubMed ID: 35565751
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stereoselective formation and metabolism of 4-hydroxy-retinoic Acid enantiomers by cytochrome p450 enzymes.
    Shimshoni JA; Roberts AG; Scian M; Topletz AR; Blankert SA; Halpert JR; Nelson WL; Isoherranen N
    J Biol Chem; 2012 Dec; 287(50):42223-32. PubMed ID: 23071109
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel tetralone-derived retinoic acid metabolism blocking agents: synthesis and in vitro evaluation with liver microsomal and MCF-7 CYP26A1 cell assays.
    Yee SW; Jarno L; Gomaa MS; Elford C; Ooi LL; Coogan MP; McClelland R; Nicholson RI; Evans BA; Brancale A; Simons C
    J Med Chem; 2005 Nov; 48(23):7123-31. PubMed ID: 16279770
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Development and Characterization of Novel and Selective Inhibitors of Cytochrome P450 CYP26A1, the Human Liver Retinoic Acid Hydroxylase.
    Diaz P; Huang W; Keyari CM; Buttrick B; Price L; Guilloteau N; Tripathy S; Sperandio VG; Fronczek FR; Astruc-Diaz F; Isoherranen N
    J Med Chem; 2016 Mar; 59(6):2579-95. PubMed ID: 26918322
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cloning of a novel retinoic-acid metabolizing cytochrome P450, Cyp26B1, and comparative expression analysis with Cyp26A1 during early murine development.
    MacLean G; Abu-Abed S; Dollé P; Tahayato A; Chambon P; Petkovich M
    Mech Dev; 2001 Sep; 107(1-2):195-201. PubMed ID: 11520679
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CYP26C1 Is a Hydroxylase of Multiple Active Retinoids and Interacts with Cellular Retinoic Acid Binding Proteins.
    Zhong G; Ortiz D; Zelter A; Nath A; Isoherranen N
    Mol Pharmacol; 2018 May; 93(5):489-503. PubMed ID: 29476041
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Retinoic acid-metabolizing enzyme cytochrome P450 26a1 (cyp26a1) is essential for implantation: functional study of its role in early pregnancy.
    Han BC; Xia HF; Sun J; Yang Y; Peng JP
    J Cell Physiol; 2010 May; 223(2):471-9. PubMed ID: 20112286
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis, and biological evaluation of amide imidazole derivatives as novel metabolic enzyme CYP26A1 inhibitors.
    Sun B; Liu K; Han J; Zhao LY; Su X; Lin B; Zhao DM; Cheng MS
    Bioorg Med Chem; 2015 Oct; 23(20):6763-73. PubMed ID: 26365710
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Knockout of Cyp26a1 and Cyp26b1 during postnatal life causes reduced lifespan, dermatitis, splenomegaly, and systemic inflammation in mice.
    Snyder JM; Zhong G; Hogarth C; Huang W; Topping T; LaFrance J; Palau L; Czuba LC; Griswold M; Ghiaur G; Isoherranen N
    FASEB J; 2020 Dec; 34(12):15788-15804. PubMed ID: 33105029
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A comparison of the roles of peroxisome proliferator-activated receptor and retinoic acid receptor on CYP26 regulation.
    Tay S; Dickmann L; Dixit V; Isoherranen N
    Mol Pharmacol; 2010 Feb; 77(2):218-27. PubMed ID: 19884280
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Retinoic acid-metabolizing enzyme cytochrome P450 26A1 promotes skin carcinogenesis induced by 7,12-dimethylbenz[a]anthracene.
    Osanai M; Takasawa A; Takasawa K; Murata M; Sawada N
    Oncol Lett; 2018 Jun; 15(6):9987-9993. PubMed ID: 29928370
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.