BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 26627716)

  • 1. Type I interferons mediate pancreatic toxicities of PERK inhibition.
    Yu Q; Zhao B; Gui J; Katlinski KV; Brice A; Gao Y; Li C; Kushner JA; Koumenis C; Diehl JA; Fuchs SY
    Proc Natl Acad Sci U S A; 2015 Dec; 112(50):15420-5. PubMed ID: 26627716
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Uncoupling proteostasis and development in vitro with a small molecule inhibitor of the pancreatic endoplasmic reticulum kinase, PERK.
    Harding HP; Zyryanova AF; Ron D
    J Biol Chem; 2012 Dec; 287(53):44338-44. PubMed ID: 23148209
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Virus-induced unfolded protein response attenuates antiviral defenses via phosphorylation-dependent degradation of the type I interferon receptor.
    Liu J; HuangFu WC; Kumar KG; Qian J; Casey JP; Hamanaka RB; Grigoriadou C; Aldabe R; Diehl JA; Fuchs SY
    Cell Host Microbe; 2009 Jan; 5(1):72-83. PubMed ID: 19154989
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Attenuation of PERK enhances glucose-stimulated insulin secretion in islets.
    Kim MJ; Min SH; Shin SY; Kim MN; Lee H; Jang JY; Kim SW; Park KS; Jung HS
    J Endocrinol; 2018 Mar; 236(3):125-136. PubMed ID: 29273589
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PERK is required in the adult pancreas and is essential for maintenance of glucose homeostasis.
    Gao Y; Sartori DJ; Li C; Yu QC; Kushner JA; Simon MC; Diehl JA
    Mol Cell Biol; 2012 Dec; 32(24):5129-39. PubMed ID: 23071091
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of p38 protein kinase in the ligand-independent ubiquitination and down-regulation of the IFNAR1 chain of type I interferon receptor.
    Bhattacharya S; Qian J; Tzimas C; Baker DP; Koumenis C; Diehl JA; Fuchs SY
    J Biol Chem; 2011 Jun; 286(25):22069-76. PubMed ID: 21540188
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inducible priming phosphorylation promotes ligand-independent degradation of the IFNAR1 chain of type I interferon receptor.
    Bhattacharya S; HuangFu WC; Liu J; Veeranki S; Baker DP; Koumenis C; Diehl JA; Fuchs SY
    J Biol Chem; 2010 Jan; 285(4):2318-25. PubMed ID: 19948722
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas.
    Zhang P; McGrath B; Li S; Frank A; Zambito F; Reinert J; Gannon M; Ma K; McNaughton K; Cavener DR
    Mol Cell Biol; 2002 Jun; 22(11):3864-74. PubMed ID: 11997520
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Microscopic and ultrastructural features in Wolcott-Rallison syndrome, a permanent neonatal diabetes mellitus: about two autopsy cases.
    Collardeau-Frachon S; Vasiljevic A; Jouvet A; Bouvier R; Senée V; Nicolino M
    Pediatr Diabetes; 2015 Nov; 16(7):510-20. PubMed ID: 25131821
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Downregulation of the IFNAR1 chain of type 1 interferon receptor contributes to the maintenance of the haematopoietic stem cells.
    Gui J; Zhao B; Lyu K; Tong W; Fuchs SY
    Cancer Biol Ther; 2017 Jul; 18(7):534-543. PubMed ID: 28678581
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Anti-tumorigenic effects of Type 1 interferon are subdued by integrated stress responses.
    Bhattacharya S; HuangFu WC; Dong G; Qian J; Baker DP; Karar J; Koumenis C; Diehl JA; Fuchs SY
    Oncogene; 2013 Sep; 32(36):4214-21. PubMed ID: 23045272
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival.
    Harding HP; Zeng H; Zhang Y; Jungries R; Chung P; Plesken H; Sabatini DD; Ron D
    Mol Cell; 2001 Jun; 7(6):1153-63. PubMed ID: 11430819
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The PKR-Like Endoplasmic Reticulum Kinase Promotes the Dissemination of Myc-Induced Leukemic Cells.
    Gui J; Katlinski KV; Koumenis C; Diehl JA; Fuchs SY
    Mol Cancer Res; 2019 Jul; 17(7):1450-1458. PubMed ID: 30902831
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased levels of type 1 interferon in a type 1 diabetic mouse model induce the elimination of B cells from the periphery by apoptosis and increase their retention in the spleen.
    Badr BM; Moustafa NA; Eldien HM; Mohamed AO; Ibrahim HM; El-Elaimy IA; Mahmoud MH; Badr G
    Cell Physiol Biochem; 2015; 35(1):137-47. PubMed ID: 25591757
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of the unfolded protein response impedes tumor cell adaptation to proteotoxic stress: a PERK for hepatocellular carcinoma therapy.
    Vandewynckel YP; Laukens D; Bogaerts E; Paridaens A; Van den Bussche A; Verhelst X; Van Steenkiste C; Descamps B; Vanhove C; Libbrecht L; De Rycke R; Lambrecht BN; Geerts A; Janssens S; Van Vlierberghe H
    Hepatol Int; 2015 Jan; 9(1):93-104. PubMed ID: 25598862
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Deficiency in type I interferon signaling prevents the early interferon-induced gene signature in pancreatic islets but not type 1 diabetes in NOD mice.
    Quah HS; Miranda-Hernandez S; Khoo A; Harding A; Fynch S; Elkerbout L; Brodnicki TC; Baxter AG; Kay TW; Thomas HE; Graham KL
    Diabetes; 2014 Mar; 63(3):1032-40. PubMed ID: 24353186
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Asparagine Synthetase Is Highly Expressed at Baseline in the Pancreas Through Heightened PERK Signaling.
    Mukherjee A; Ahmed N; Rose FT; Ahmad AN; Javed TA; Wen L; Bottino R; Xiao X; Kilberg MS; Husain SZ
    Cell Mol Gastroenterol Hepatol; 2020; 9(1):1-13. PubMed ID: 31421261
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses.
    Mandula JK; Chang S; Mohamed E; Jimenez R; Sierra-Mondragon RA; Chang DC; Obermayer AN; Moran-Segura CM; Das S; Vazquez-Martinez JA; Prieto K; Chen A; Smalley KSM; Czerniecki B; Forsyth P; Koya RC; Ruffell B; Cubillos-Ruiz JR; Munn DH; Shaw TI; Conejo-Garcia JR; Rodriguez PC
    Cancer Cell; 2022 Oct; 40(10):1145-1160.e9. PubMed ID: 36150390
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pancreatic islet-autonomous effect of arsenic on insulin secretion through endoplasmic reticulum stress-autophagy pathway.
    Wu W; Yao X; Jiang L; Zhang Q; Bai J; Qiu T; Yang L; Gao N; Yang G; Liu X; Chen M; Sun X
    Food Chem Toxicol; 2018 Jan; 111():19-26. PubMed ID: 29111283
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pancreatic endoplasmic reticulum kinase activation promotes medulloblastoma cell migration and invasion through induction of vascular endothelial growth factor A.
    Jamison S; Lin Y; Lin W
    PLoS One; 2015; 10(3):e0120252. PubMed ID: 25794107
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.