These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

611 related articles for article (PubMed ID: 26637797)

  • 1. Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice.
    Peters OM; Cabrera GT; Tran H; Gendron TF; McKeon JE; Metterville J; Weiss A; Wightman N; Salameh J; Kim J; Sun H; Boylan KB; Dickson D; Kennedy Z; Lin Z; Zhang YJ; Daughrity L; Jung C; Gao FB; Sapp PC; Horvitz HR; Bosco DA; Brown SP; de Jong P; Petrucelli L; Mueller C; Brown RH
    Neuron; 2015 Dec; 88(5):902-909. PubMed ID: 26637797
    [TBL] [Abstract][Full Text] [Related]  

  • 2. C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD.
    O'Rourke JG; Bogdanik L; Muhammad AKMG; Gendron TF; Kim KJ; Austin A; Cady J; Liu EY; Zarrow J; Grant S; Ho R; Bell S; Carmona S; Simpkinson M; Lall D; Wu K; Daughrity L; Dickson DW; Harms MB; Petrucelli L; Lee EB; Lutz CM; Baloh RH
    Neuron; 2015 Dec; 88(5):892-901. PubMed ID: 26637796
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DDX3X overexpression decreases dipeptide repeat proteins in a mouse model of C9ORF72-ALS/FTD.
    Fu X; Zhang Z; Hayes LR; Wright N; Asbury J; Li S; Ye Y; Sun S
    Exp Neurol; 2024 Jun; 376():114768. PubMed ID: 38556190
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular Mechanisms of Neurodegeneration Related to
    Babić Leko M; Župunski V; Kirincich J; Smilović D; Hortobágyi T; Hof PR; Šimić G
    Behav Neurol; 2019; 2019():2909168. PubMed ID: 30774737
    [TBL] [Abstract][Full Text] [Related]  

  • 5. C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels.
    Beckers J; Tharkeshwar AK; Van Damme P
    Autophagy; 2021 Nov; 17(11):3306-3322. PubMed ID: 33632058
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Modelling C9ORF72 hexanucleotide repeat expansion in amyotrophic lateral sclerosis and frontotemporal dementia.
    Stepto A; Gallo JM; Shaw CE; Hirth F
    Acta Neuropathol; 2014 Mar; 127(3):377-89. PubMed ID: 24366528
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia.
    Zu T; Liu Y; Bañez-Coronel M; Reid T; Pletnikova O; Lewis J; Miller TM; Harms MB; Falchook AE; Subramony SH; Ostrow LW; Rothstein JD; Troncoso JC; Ranum LP
    Proc Natl Acad Sci U S A; 2013 Dec; 110(51):E4968-77. PubMed ID: 24248382
    [TBL] [Abstract][Full Text] [Related]  

  • 8. There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS.
    Gitler AD; Tsuiji H
    Brain Res; 2016 Sep; 1647():19-29. PubMed ID: 27059391
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene.
    Wen X; Westergard T; Pasinelli P; Trotti D
    Neurosci Lett; 2017 Jan; 636():16-26. PubMed ID: 27619540
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BET bromodomain inhibitors PFI-1 and JQ1 are identified in an epigenetic compound screen to enhance C9ORF72 gene expression and shown to ameliorate C9ORF72-associated pathological and behavioral abnormalities in a C9ALS/FTD model.
    Quezada E; Cappelli C; Diaz I; Jury N; Wightman N; Brown RH; Montecino M; van Zundert B
    Clin Epigenetics; 2021 Mar; 13(1):56. PubMed ID: 33726839
    [TBL] [Abstract][Full Text] [Related]  

  • 11. C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins.
    Mizielinska S; Grönke S; Niccoli T; Ridler CE; Clayton EL; Devoy A; Moens T; Norona FE; Woollacott IOC; Pietrzyk J; Cleverley K; Nicoll AJ; Pickering-Brown S; Dols J; Cabecinha M; Hendrich O; Fratta P; Fisher EMC; Partridge L; Isaacs AM
    Science; 2014 Sep; 345(6201):1192-1194. PubMed ID: 25103406
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Stable transgenic C9orf72 zebrafish model key aspects of the ALS/FTD phenotype and reveal novel pathological features.
    Shaw MP; Higginbottom A; McGown A; Castelli LM; James E; Hautbergue GM; Shaw PJ; Ramesh TM
    Acta Neuropathol Commun; 2018 Nov; 6(1):125. PubMed ID: 30454072
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Retention of hexanucleotide repeat-containing intron in C9orf72 mRNA: implications for the pathogenesis of ALS/FTD.
    Niblock M; Smith BN; Lee YB; Sardone V; Topp S; Troakes C; Al-Sarraj S; Leblond CS; Dion PA; Rouleau GA; Shaw CE; Gallo JM
    Acta Neuropathol Commun; 2016 Feb; 4():18. PubMed ID: 26916632
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Artificial microRNA suppresses C9ORF72 variants and decreases toxic dipeptide repeat proteins in vivo.
    Cabrera GT; Meijboom KE; Abdallah A; Tran H; Foster Z; Weiss A; Wightman N; Stock R; Gendron T; Gruntman A; Giampetruzzi A; Petrucelli L; Brown RH; Mueller C
    Gene Ther; 2024 Mar; 31(3-4):105-118. PubMed ID: 37752346
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Therapeutic reduction of GGGGCC repeat RNA levels by hnRNPA3 suppresses neurodegeneration in Drosophila models of C9orf72-linked ALS/FTD.
    Taminato T; Takeuchi T; Ueyama M; Mori K; Ikeda M; Mochizuki H; Nagai Y
    Hum Mol Genet; 2023 May; 32(10):1673-1682. PubMed ID: 36611007
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The DNA damage response (DDR) is induced by the C9orf72 repeat expansion in amyotrophic lateral sclerosis.
    Farg MA; Konopka A; Soo KY; Ito D; Atkin JD
    Hum Mol Genet; 2017 Aug; 26(15):2882-2896. PubMed ID: 28481984
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons.
    Almeida S; Gascon E; Tran H; Chou HJ; Gendron TF; Degroot S; Tapper AR; Sellier C; Charlet-Berguerand N; Karydas A; Seeley WW; Boxer AL; Petrucelli L; Miller BL; Gao FB
    Acta Neuropathol; 2013 Sep; 126(3):385-99. PubMed ID: 23836290
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The clinical and pathological phenotype of C9ORF72 hexanucleotide repeat expansions.
    Simón-Sánchez J; Dopper EG; Cohn-Hokke PE; Hukema RK; Nicolaou N; Seelaar H; de Graaf JR; de Koning I; van Schoor NM; Deeg DJ; Smits M; Raaphorst J; van den Berg LH; Schelhaas HJ; De Die-Smulders CE; Majoor-Krakauer D; Rozemuller AJ; Willemsen R; Pijnenburg YA; Heutink P; van Swieten JC
    Brain; 2012 Mar; 135(Pt 3):723-35. PubMed ID: 22300876
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insights into the pathogenic mechanisms of Chromosome 9 open reading frame 72 (C9orf72) repeat expansions.
    Todd TW; Petrucelli L
    J Neurochem; 2016 Aug; 138 Suppl 1():145-62. PubMed ID: 27016280
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A C9ORF72 BAC mouse model recapitulates key epigenetic perturbations of ALS/FTD.
    Esanov R; Cabrera GT; Andrade NS; Gendron TF; Brown RH; Benatar M; Wahlestedt C; Mueller C; Zeier Z
    Mol Neurodegener; 2017 Jun; 12(1):46. PubMed ID: 28606110
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.