These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 26638620)

  • 1. [Function of Proto-oncogene Product PPM1D and Development of PPM1D Inhibitors for Cancer Chemotherapy].
    Kamada R; Chuman Y; Kozakai Y; Sakaguchi K
    Seikagaku; 2015 Oct; 87(5):531-8. PubMed ID: 26638620
    [No Abstract]   [Full Text] [Related]  

  • 2. Novel inhibitors targeting PPM1D phosphatase potently suppress cancer cell proliferation.
    Ogasawara S; Kiyota Y; Chuman Y; Kowata A; Yoshimura F; Tanino K; Kamada R; Sakaguchi K
    Bioorg Med Chem; 2015 Oct; 23(19):6246-9. PubMed ID: 26358280
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fortifying p53 - beyond Mdm2 inhibitors.
    Sriraman A; Li Y; Dobbelstein M
    Aging (Albany NY); 2016 Sep; 8(9):1836-1837. PubMed ID: 27688014
    [No Abstract]   [Full Text] [Related]  

  • 4. A small molecule inhibitor of p53-inducible protein phosphatase PPM1D.
    Yagi H; Chuman Y; Kozakai Y; Imagawa T; Takahashi Y; Yoshimura F; Tanino K; Sakaguchi K
    Bioorg Med Chem Lett; 2012 Jan; 22(1):729-32. PubMed ID: 22115592
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice.
    Nannenga B; Lu X; Dumble M; Van Maanen M; Nguyen TA; Sutton R; Kumar TR; Donehower LA
    Mol Carcinog; 2006 Aug; 45(8):594-604. PubMed ID: 16652371
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of the active site and a unique uncompetitive inhibitor of the PPM1-type protein phosphatase PPM1D.
    Chuman Y; Yagi H; Fukuda T; Nomura T; Matsukizono M; Shimohigashi Y; Sakaguchi K
    Protein Pept Lett; 2008; 15(9):938-48. PubMed ID: 18991770
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of C-terminal truncated PPM1D enhances the effect of doxorubicin on cell viability in human colorectal carcinoma cell line.
    Kozakai Y; Kamada R; Kiyota Y; Yoshimura F; Tanino K; Sakaguchi K
    Bioorg Med Chem Lett; 2014 Dec; 24(24):5593-5596. PubMed ID: 25466181
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting the PPM1D phenotype; 2,4-bisarylthiazoles cause highly selective apoptosis in PPM1D amplified cell-lines.
    Cheeseman MD; Faisal A; Rayter S; Barbeau OR; Kalusa A; Westlake M; Burke R; Swan M; van Montfort R; Linardopoulos S; Jones K
    Bioorg Med Chem Lett; 2014 Aug; 24(15):3469-74. PubMed ID: 24953599
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D.
    Rayter S; Elliott R; Travers J; Rowlands MG; Richardson TB; Boxall K; Jones K; Linardopoulos S; Workman P; Aherne W; Lord CJ; Ashworth A
    Oncogene; 2008 Feb; 27(8):1036-44. PubMed ID: 17700519
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PPM1D activity promotes cellular transformation by preventing senescence and cell death.
    Stoyanov M; Martinikova AS; Matejkova K; Horackova K; Zemankova P; Burdova K; Zemanova Z; Kleiblova P; Kleibl Z; Macurek L
    Oncogene; 2024 Oct; 43(42):3081-3093. PubMed ID: 39237765
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PPM1D phosphatase, a target of p53 and RBM38 RNA-binding protein, inhibits p53 mRNA translation via dephosphorylation of RBM38.
    Zhang M; Xu E; Zhang J; Chen X
    Oncogene; 2015 Nov; 34(48):5900-11. PubMed ID: 25823026
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PPM1D is a potential therapeutic target in ovarian clear cell carcinomas.
    Tan DS; Lambros MB; Rayter S; Natrajan R; Vatcheva R; Gao Q; Marchiò C; Geyer FC; Savage K; Parry S; Fenwick K; Tamber N; Mackay A; Dexter T; Jameson C; McCluggage WG; Williams A; Graham A; Faratian D; El-Bahrawy M; Paige AJ; Gabra H; Gore ME; Zvelebil M; Lord CJ; Kaye SB; Ashworth A; Reis-Filho JS
    Clin Cancer Res; 2009 Apr; 15(7):2269-80. PubMed ID: 19293255
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23.
    Li J; Yang Y; Peng Y; Austin RJ; van Eyndhoven WG; Nguyen KC; Gabriele T; McCurrach ME; Marks JR; Hoey T; Lowe SW; Powers S
    Nat Genet; 2002 Jun; 31(2):133-4. PubMed ID: 12021784
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Smaller protein, larger therapeutic potential: PPM1D as a new therapeutic target in brainstem glioma.
    Reitman ZJ
    Pharmacogenomics; 2014 Sep; 15(13):1639-41. PubMed ID: 25410889
    [No Abstract]   [Full Text] [Related]  

  • 15. Akt confers cisplatin chemoresistance in human gynecological carcinoma cells by modulating PPM1D stability.
    Ali AY; Kim JY; Pelletier JF; Vanderhyden BC; Bachvarov DR; Tsang BK
    Mol Carcinog; 2015 Nov; 54(11):1301-14. PubMed ID: 25154814
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulatory cascades of protein phosphatases: implications for cancer treatment.
    Jailkhani N; Chaudhri VK; Rao KV
    Anticancer Agents Med Chem; 2011 Jan; 11(1):64-77. PubMed ID: 21214508
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of differentially expressed genes after PPM1D silencing in breast cancer.
    Pärssinen J; Alarmo EL; Khan S; Karhu R; Vihinen M; Kallioniemi A
    Cancer Lett; 2008 Jan; 259(1):61-70. PubMed ID: 17977650
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair.
    Lu X; Bocangel D; Nannenga B; Yamaguchi H; Appella E; Donehower LA
    Mol Cell; 2004 Aug; 15(4):621-34. PubMed ID: 15327777
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PP2Cdelta (Ppm1d, WIP1), an endogenous inhibitor of p38 MAPK, is regulated along with Trp53 and Cdkn2a following p38 MAPK inhibition during mouse preimplantation development.
    Hickson JA; Fong B; Watson PH; Watson AJ
    Mol Reprod Dev; 2007 Jul; 74(7):821-34. PubMed ID: 17219434
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Strategies for Targeting Serine/Threonine Protein Phosphatases with Small Molecules in Cancer.
    Zhang Q; Fan Z; Zhang L; You Q; Wang L
    J Med Chem; 2021 Jul; 64(13):8916-8938. PubMed ID: 34156850
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.