194 related articles for article (PubMed ID: 26644182)
1. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells.
Ortmann B; Bensaddek D; Carvalhal S; Moser SC; Mudie S; Griffis ER; Swedlow JR; Lamond AI; Rocha S
J Cell Sci; 2016 Jan; 129(1):191-205. PubMed ID: 26644182
[TBL] [Abstract][Full Text] [Related]
2. PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192.
Moser SC; Bensaddek D; Ortmann B; Maure JF; Mudie S; Blow JJ; Lamond AI; Swedlow JR; Rocha S
Dev Cell; 2013 Aug; 26(4):381-92. PubMed ID: 23932902
[TBL] [Abstract][Full Text] [Related]
3. Docetaxel induced-JNK2/PHD1 signaling pathway increases degradation of HIF-1α and causes cancer cell death under hypoxia.
Oh ET; Kim CW; Kim SJ; Lee JS; Hong SS; Park HJ
Sci Rep; 2016 Jun; 6():27382. PubMed ID: 27263528
[TBL] [Abstract][Full Text] [Related]
4. Iron chelation and 2-oxoglutarate-dependent dioxygenase inhibition suppress mantle cell lymphoma's cyclin D1.
Babosova O; Kapralova K; Raskova Kafkova L; Korinek V; Divoky V; Prchal JT; Lanikova L
J Cell Mol Med; 2019 Nov; 23(11):7785-7795. PubMed ID: 31517438
[TBL] [Abstract][Full Text] [Related]
5. Hypoxia-dependent regulation of PHD1: cloning and characterization of the human PHD1/EGLN2 gene promoter.
Erez N; Stambolsky P; Shats I; Milyavsky M; Kachko T; Rotter V
FEBS Lett; 2004 Jun; 567(2-3):311-5. PubMed ID: 15178343
[TBL] [Abstract][Full Text] [Related]
6. Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor.
Appelhoff RJ; Tian YM; Raval RR; Turley H; Harris AL; Pugh CW; Ratcliffe PJ; Gleadle JM
J Biol Chem; 2004 Sep; 279(37):38458-65. PubMed ID: 15247232
[TBL] [Abstract][Full Text] [Related]
7. PHD1 interacts with ATF4 and negatively regulates its transcriptional activity without prolyl hydroxylation.
Hiwatashi Y; Kanno K; Takasaki C; Goryo K; Sato T; Torii S; Sogawa K; Yasumoto K
Exp Cell Res; 2011 Dec; 317(20):2789-99. PubMed ID: 21951999
[TBL] [Abstract][Full Text] [Related]
8. The prolyl hydroxylase enzymes are positively associated with hypoxia-inducible factor-1α and vascular endothelial growth factor in human breast cancer and alter in response to primary systemic treatment with epirubicin and tamoxifen.
Fox SB; Generali D; Berruti A; Brizzi MP; Campo L; Bonardi S; Bersiga A; Allevi G; Milani M; Aguggini S; Mele T; Dogliotti L; Bottini A; Harris AL
Breast Cancer Res; 2011 Feb; 13(1):R16. PubMed ID: 21291529
[TBL] [Abstract][Full Text] [Related]
9. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
[TBL] [Abstract][Full Text] [Related]
10. The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia.
Di Conza G; Trusso Cafarello S; Loroch S; Mennerich D; Deschoemaeker S; Di Matteo M; Ehling M; Gevaert K; Prenen H; Zahedi RP; Sickmann A; Kietzmann T; Moretti F; Mazzone M
Cell Rep; 2017 Feb; 18(7):1699-1712. PubMed ID: 28199842
[TBL] [Abstract][Full Text] [Related]
11. Mucosal inflammation downregulates PHD1 expression promoting a barrier-protective HIF-1α response in ulcerative colitis patients.
Brown E; Rowan C; Strowitzki MJ; Fagundes RR; Faber KN; Güntsch A; Halligan DN; Kugler J; Jones F; Lee CT; Doherty G; Taylor CT
FASEB J; 2020 Mar; 34(3):3732-3742. PubMed ID: 31944416
[TBL] [Abstract][Full Text] [Related]
12. The PHD1 oxygen sensor in health and disease.
Kennel KB; Burmeister J; Schneider M; Taylor CT
J Physiol; 2018 Sep; 596(17):3899-3913. PubMed ID: 29435987
[TBL] [Abstract][Full Text] [Related]
13. HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia.
Berra E; Benizri E; Ginouvès A; Volmat V; Roux D; Pouysségur J
EMBO J; 2003 Aug; 22(16):4082-90. PubMed ID: 12912907
[TBL] [Abstract][Full Text] [Related]
14. Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer.
Rawluszko AA; Bujnicka KE; Horbacka K; Krokowicz P; Jagodziński PP
BMC Cancer; 2013 Nov; 13():526. PubMed ID: 24195777
[TBL] [Abstract][Full Text] [Related]
15. Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxia.
Fujita N; Markova D; Anderson DG; Chiba K; Toyama Y; Shapiro IM; Risbud MV
J Biol Chem; 2012 May; 287(20):16975-86. PubMed ID: 22451659
[TBL] [Abstract][Full Text] [Related]
16. Over-expression of prolyl hydroxylase-1 blocks NF-κB-mediated cyclin D1 expression and proliferation in lung carcinoma cells.
Xie X; Xiao H; Ding F; Zhong H; Zhu J; Ma N; Mei J
Cancer Genet; 2014 May; 207(5):188-94. PubMed ID: 24935227
[TBL] [Abstract][Full Text] [Related]
17. Studies on the Substrate Selectivity of the Hypoxia-Inducible Factor Prolyl Hydroxylase 2 Catalytic Domain.
Abboud MI; Chowdhury R; Leung IKH; Lippl K; Loenarz C; Claridge TDW; Schofield CJ
Chembiochem; 2018 Nov; 19(21):2262-2267. PubMed ID: 30144273
[TBL] [Abstract][Full Text] [Related]
18. The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity.
Foxler DE; Bridge KS; James V; Webb TM; Mee M; Wong SC; Feng Y; Constantin-Teodosiu D; Petursdottir TE; Bjornsson J; Ingvarsson S; Ratcliffe PJ; Longmore GD; Sharp TV
Nat Cell Biol; 2012 Jan; 14(2):201-8. PubMed ID: 22286099
[TBL] [Abstract][Full Text] [Related]
19. Changes in Hypoxia-Inducible Factor-1 (HIF-1) and Regulatory Prolyl Hydroxylase (PHD) Enzymes Following Hypoxic-Ischemic Injury in the Neonatal Rat.
Chu HX; Jones NM
Neurochem Res; 2016 Mar; 41(3):515-22. PubMed ID: 26108712
[TBL] [Abstract][Full Text] [Related]
20. Selective inhibition of hypoxia-inducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathways.
Siddiq A; Aminova LR; Troy CM; Suh K; Messer Z; Semenza GL; Ratan RR
J Neurosci; 2009 Jul; 29(27):8828-38. PubMed ID: 19587290
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]