These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

295 related articles for article (PubMed ID: 26646749)

  • 1. Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells.
    Russo I; Berti G; Plotegher N; Bernardo G; Filograna R; Bubacco L; Greggio E
    J Neuroinflammation; 2015 Dec; 12():230. PubMed ID: 26646749
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4.
    Russo I; Di Benedetto G; Kaganovich A; Ding J; Mercatelli D; Morari M; Cookson MR; Bubacco L; Greggio E
    J Neuroinflammation; 2018 Oct; 15(1):297. PubMed ID: 30368241
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Leucine-rich repeat kinase 2 modulates neuroinflammation and neurotoxicity in models of human immunodeficiency virus 1-associated neurocognitive disorders.
    Puccini JM; Marker DF; Fitzgerald T; Barbieri J; Kim CS; Miller-Rhodes P; Lu SM; Dewhurst S; Gelbard HA
    J Neurosci; 2015 Apr; 35(13):5271-83. PubMed ID: 25834052
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Impaired inflammatory responses in murine Lrrk2-knockdown brain microglia.
    Kim B; Yang MS; Choi D; Kim JH; Kim HS; Seol W; Choi S; Jou I; Kim EY; Joe EH
    PLoS One; 2012; 7(4):e34693. PubMed ID: 22496842
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils.
    Russo I; Kaganovich A; Ding J; Landeck N; Mamais A; Varanita T; Biosa A; Tessari I; Bubacco L; Greggio E; Cookson MR
    Neurobiol Dis; 2019 Sep; 129():67-78. PubMed ID: 31102768
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Leucine-rich repeat kinase 2 (LRRK2) regulates α-synuclein clearance in microglia.
    Maekawa T; Sasaoka T; Azuma S; Ichikawa T; Melrose HL; Farrer MJ; Obata F
    BMC Neurosci; 2016 Nov; 17(1):77. PubMed ID: 27903237
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LRRK2 kinase plays a critical role in manganese-induced inflammation and apoptosis in microglia.
    Kim J; Pajarillo E; Rizor A; Son DS; Lee J; Aschner M; Lee E
    PLoS One; 2019; 14(1):e0210248. PubMed ID: 30645642
    [TBL] [Abstract][Full Text] [Related]  

  • 8. LRRK2 and neuroinflammation: partners in crime in Parkinson's disease?
    Russo I; Bubacco L; Greggio E
    J Neuroinflammation; 2014 Mar; 11():52. PubMed ID: 24655756
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutations in LRRK2 impair NF-κB pathway in iPSC-derived neurons.
    López de Maturana R; Lang V; Zubiarrain A; Sousa A; Vázquez N; Gorostidi A; Águila J; López de Munain A; Rodríguez M; Sánchez-Pernaute R
    J Neuroinflammation; 2016 Nov; 13(1):295. PubMed ID: 27863501
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Parkinson's disease-linked leucine-rich repeat kinase 2(R1441G) mutation increases proinflammatory cytokine release from activated primary microglial cells and resultant neurotoxicity.
    Gillardon F; Schmid R; Draheim H
    Neuroscience; 2012 Apr; 208():41-8. PubMed ID: 22342962
    [TBL] [Abstract][Full Text] [Related]  

  • 11. LRRK2 Inhibition Mitigates the Neuroinflammation Caused by TLR2-Specific α-Synuclein and Alleviates Neuroinflammation-Derived Dopaminergic Neuronal Loss.
    Ho DH; Nam D; Seo M; Park SW; Seol W; Son I
    Cells; 2022 Mar; 11(5):. PubMed ID: 35269482
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of Nur77 in microglia attenuates proinflammatory mediators production and protects dopaminergic neurons from inflammation-induced cell death.
    Liu TY; Yang XY; Zheng LT; Wang GH; Zhen XC
    J Neurochem; 2017 Feb; 140(4):589-604. PubMed ID: 27889907
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel LRRK2 GTP-binding inhibitors reduced degeneration in Parkinson's disease cell and mouse models.
    Li T; Yang D; Zhong S; Thomas JM; Xue F; Liu J; Kong L; Voulalas P; Hassan HE; Park JS; MacKerell AD; Smith WW
    Hum Mol Genet; 2014 Dec; 23(23):6212-22. PubMed ID: 24993787
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cysteinyl Leukotriene Receptor 2 is Involved in Inflammation and Neuronal Damage by Mediating Microglia M1/M2 Polarization through NF-κB Pathway.
    Zhao R; Ying M; Gu S; Yin W; Li Y; Yuan H; Fang S; Li M
    Neuroscience; 2019 Dec; 422():99-118. PubMed ID: 31726033
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease.
    Schapansky J; Nardozzi JD; LaVoie MJ
    Neuroscience; 2015 Aug; 302():74-88. PubMed ID: 25284317
    [TBL] [Abstract][Full Text] [Related]  

  • 16. LRRK2 kinase inhibition prevents pathological microglial phagocytosis in response to HIV-1 Tat protein.
    Marker DF; Puccini JM; Mockus TE; Barbieri J; Lu SM; Gelbard HA
    J Neuroinflammation; 2012 Nov; 9():261. PubMed ID: 23190742
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Leucine-rich repeat kinase-2 (LRRK2) modulates microglial phenotype and dopaminergic neurodegeneration.
    Dwyer Z; Rudyk C; Thompson A; Farmer K; Fenner B; Fortin T; Derksen A; Sun H; Hayley S;
    Neurobiol Aging; 2020 Jul; 91():45-55. PubMed ID: 32247534
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphorylation of p53 by LRRK2 induces microglial tumor necrosis factor α-mediated neurotoxicity.
    Ho DH; Seol W; Eun JH; Son IH
    Biochem Biophys Res Commun; 2017 Jan; 482(4):1088-1094. PubMed ID: 27914807
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Changes in matrix metalloprotease activity and progranulin levels may contribute to the pathophysiological function of mutant leucine-rich repeat kinase 2.
    Caesar M; Felk S; Zach S; Brønstad G; Aasly JO; Gasser T; Gillardon F
    Glia; 2014 Jul; 62(7):1075-92. PubMed ID: 24652679
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Redox regulation of NF-κB p50 and M1 polarization in microglia.
    Taetzsch T; Levesque S; McGraw C; Brookins S; Luqa R; Bonini MG; Mason RP; Oh U; Block ML
    Glia; 2015 Mar; 63(3):423-40. PubMed ID: 25331559
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.