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3. The longevity gene INDY (I'm Not Dead Yet) in metabolic control: Potential as pharmacological target. Willmes DM; Kurzbach A; Henke C; Schumann T; Zahn G; Heifetz A; Jordan J; Helfand SL; Birkenfeld AL Pharmacol Ther; 2018 May; 185():1-11. PubMed ID: 28987323 [TBL] [Abstract][Full Text] [Related]
4. The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism. von Loeffelholz C; Lieske S; Neuschäfer-Rube F; Willmes DM; Raschzok N; Sauer IM; König J; Fromm MF; Horn P; Chatzigeorgiou A; Pathe-Neuschäfer-Rube A; Jordan J; Pfeiffer AFH; Mingrone G; Bornstein SR; Stroehle P; Harms C; Wunderlich FT; Helfand SL; Bernier M; de Cabo R; Shulman GI; Chavakis T; Püschel GP; Birkenfeld AL Hepatology; 2017 Aug; 66(2):616-630. PubMed ID: 28133767 [TBL] [Abstract][Full Text] [Related]
5. Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice. Birkenfeld AL; Lee HY; Guebre-Egziabher F; Alves TC; Jurczak MJ; Jornayvaz FR; Zhang D; Hsiao JJ; Martin-Montalvo A; Fischer-Rosinsky A; Spranger J; Pfeiffer AF; Jordan J; Fromm MF; König J; Lieske S; Carmean CM; Frederick DW; Weismann D; Knauf F; Irusta PM; De Cabo R; Helfand SL; Samuel VT; Shulman GI Cell Metab; 2011 Aug; 14(2):184-95. PubMed ID: 21803289 [TBL] [Abstract][Full Text] [Related]
6. Second-generation antisense oligonucleotides against β-catenin protect mice against diet-induced hepatic steatosis and hepatic and peripheral insulin resistance. Popov VB; Jornayvaz FR; Akgul EO; Kanda S; Jurczak MJ; Zhang D; Abudukadier A; Majumdar SK; Guigni B; Petersen KF; Manchem VP; Bhanot S; Shulman GI; Samuel VT FASEB J; 2016 Mar; 30(3):1207-17. PubMed ID: 26644352 [TBL] [Abstract][Full Text] [Related]
7. The longevity transporter mIndy (Slc13a5) as a target for treating hepatic steatosis and insulin resistance. Willmes DM; Helfand SL; Birkenfeld AL Aging (Albany NY); 2016 Feb; 8(2):208-9. PubMed ID: 26928109 [No Abstract] [Full Text] [Related]
8. INDY-A New Link to Metabolic Regulation in Animals and Humans. Rogina B Front Genet; 2017; 8():66. PubMed ID: 28596784 [TBL] [Abstract][Full Text] [Related]
9. The mammalian INDY homolog is induced by CREB in a rat model of type 2 diabetes. Neuschäfer-Rube F; Lieske S; Kuna M; Henkel J; Perry RJ; Erion DM; Pesta D; Willmes DM; Brachs S; von Loeffelholz C; Tolkachov A; Schupp M; Pathe-Neuschäfer-Rube A; Pfeiffer AF; Shulman GI; Püschel GP; Birkenfeld AL Diabetes; 2014 Mar; 63(3):1048-57. PubMed ID: 24222346 [TBL] [Abstract][Full Text] [Related]
10. Arylhydrocarbon receptor-dependent mIndy (Slc13a5) induction as possible contributor to benzo[a]pyrene-induced lipid accumulation in hepatocytes. Neuschäfer-Rube F; Schraplau A; Schewe B; Lieske S; Krützfeldt JM; Ringel S; Henkel J; Birkenfeld AL; Püschel GP Toxicology; 2015 Nov; 337():1-9. PubMed ID: 26303333 [TBL] [Abstract][Full Text] [Related]
11. INDY-From Flies to Worms, Mice, Rats, Non-Human Primates, and Humans. Mishra D; Kannan K; Meadows K; Macro J; Li M; Frankel S; Rogina B Front Aging; 2021; 2():782162. PubMed ID: 35822025 [No Abstract] [Full Text] [Related]
12. The longevity gene mIndy (I'm Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms. Willmes DM; Daniels M; Kurzbach A; Lieske S; Bechmann N; Schumann T; Henke C; El-Agroudy NN; Da Costa Goncalves AC; Peitzsch M; Hofmann A; Kanczkowski W; Kräker K; Müller DN; Morawietz H; Deussen A; Wagner M; El-Armouche A; Helfand SL; Bornstein SR; de Cabo R; Bernier M; Eisenhofer G; Tank J; Jordan J; Birkenfeld AL JCI Insight; 2021 Jan; 6(2):. PubMed ID: 33491666 [TBL] [Abstract][Full Text] [Related]
13. Nervous System Deletion of Mammalian INDY in Mice Mimics Dietary Restriction-Induced Memory Enhancement. Fan SZ; Sung CW; Tsai YH; Yeh SR; Lin WS; Wang PY J Gerontol A Biol Sci Med Sci; 2021 Jan; 76(1):50-56. PubMed ID: 32808644 [TBL] [Abstract][Full Text] [Related]
14. Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance. Choi CS; Savage DB; Kulkarni A; Yu XX; Liu ZX; Morino K; Kim S; Distefano A; Samuel VT; Neschen S; Zhang D; Wang A; Zhang XM; Kahn M; Cline GW; Pandey SK; Geisler JG; Bhanot S; Monia BP; Shulman GI J Biol Chem; 2007 Aug; 282(31):22678-88. PubMed ID: 17526931 [TBL] [Abstract][Full Text] [Related]
15. The role of INDY in metabolism, health and longevity. Rogers RP; Rogina B Front Genet; 2015; 6():204. PubMed ID: 26106407 [TBL] [Abstract][Full Text] [Related]
16. The Role of INDY in Metabolic Regulation. Willmes DM; Birkenfeld AL Comput Struct Biotechnol J; 2013; 6():e201303020. PubMed ID: 24688728 [TBL] [Abstract][Full Text] [Related]
17. CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance. Brown JM; Betters JL; Lord C; Ma Y; Han X; Yang K; Alger HM; Melchior J; Sawyer J; Shah R; Wilson MD; Liu X; Graham MJ; Lee R; Crooke R; Shulman GI; Xue B; Shi H; Yu L J Lipid Res; 2010 Nov; 51(11):3306-15. PubMed ID: 20802159 [TBL] [Abstract][Full Text] [Related]
18. Consequences of NaCT/SLC13A5/mINDY deficiency: good versus evil, separated only by the blood-brain barrier. Kopel JJ; Bhutia YD; Sivaprakasam S; Ganapathy V Biochem J; 2021 Feb; 478(3):463-486. PubMed ID: 33544126 [TBL] [Abstract][Full Text] [Related]
19. Multiple antisense oligonucleotides targeted against monoacylglycerol acyltransferase 1 (Mogat1) improve glucose metabolism independently of Mogat1. Lutkewitte AJ; Singer JM; Shew TM; Martino MR; Hall AM; He M; Finck BN Mol Metab; 2021 Jul; 49():101204. PubMed ID: 33676028 [TBL] [Abstract][Full Text] [Related]
20. Knockdown of Indy/CeNac2 extends Caenorhabditis elegans life span by inducing AMPK/aak-2. Schwarz F; Karadeniz Z; Fischer-Rosinsky A; Willmes DM; Spranger J; Birkenfeld AL Aging (Albany NY); 2015 Aug; 7(8):553-67. PubMed ID: 26318988 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]