These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

213 related articles for article (PubMed ID: 26651262)

  • 21. Biophysical Properties and Heating-Induced Aggregation of Lysine-Conjugated Antibody-Drug Conjugates.
    Gandhi AV; Arlotta KJ; Chen HN; Owen SC; Carpenter JF
    J Pharm Sci; 2018 Jul; 107(7):1858-1869. PubMed ID: 29626535
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Sensitive quantitation of low level free polysaccharide in conjugate vaccines by size exclusion chromatography-reverse phase liquid chromatography with UV detection.
    Schuchmann DC; Hou W; Creahan J; He Y; Jones MT
    J Pharm Biomed Anal; 2020 Feb; 180():113043. PubMed ID: 31864110
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Antibody-drug conjugate model fast characterization by LC-MS following IdeS proteolytic digestion.
    Wagner-Rousset E; Janin-Bussat MC; Colas O; Excoffier M; Ayoub D; Haeuw JF; Rilatt I; Perez M; Corvaïa N; Beck A
    MAbs; 2014; 6(1):273-85. PubMed ID: 24135617
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Innovative native MS methodologies for antibody drug conjugate characterization: High resolution native MS and IM-MS for average DAR and DAR distribution assessment.
    Debaene F; Boeuf A; Wagner-Rousset E; Colas O; Ayoub D; Corvaïa N; Van Dorsselaer A; Beck A; Cianférani S
    Anal Chem; 2014 Nov; 86(21):10674-83. PubMed ID: 25270580
    [TBL] [Abstract][Full Text] [Related]  

  • 25. [The Characterization of Drug-to-Antibody Ratio and Isoforms of ADCs Using LC and MS Technologies].
    Iizuka R; Kotch F; Xu A; Porter T; Shion H; Birdsall R; Chen W
    Yakugaku Zasshi; 2017; 137(5):525-528. PubMed ID: 28458283
    [TBL] [Abstract][Full Text] [Related]  

  • 26. LC/MS/MS Bioanalysis of Protein-Drug Conjugates-The Importance of Incorporating Succinimide Hydrolysis Products.
    Shi C; Goldberg S; Lin T; Dudkin V; Widdison W; Harris L; Wilhelm S; Jmeian Y; Davis D; O'Neil K; Weng N; Jian W
    Anal Chem; 2018 Apr; 90(8):5314-5321. PubMed ID: 29589741
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Conjugation site analysis of antibody-drug-conjugates (ADCs) by signature ion fingerprinting and normalized area quantitation approach using nano-liquid chromatography coupled to high resolution mass spectrometry.
    Sang H; Lu G; Liu Y; Hu Q; Xing W; Cui D; Zhou F; Zhang J; Hao H; Wang G; Ye H
    Anal Chim Acta; 2017 Feb; 955():67-78. PubMed ID: 28088282
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Native size-exclusion chromatography-mass spectrometry: suitability for antibody-drug conjugate drug-to-antibody ratio quantitation across a range of chemotypes and drug-loading levels.
    Jones J; Pack L; Hunter JH; Valliere-Douglass JF
    MAbs; 2020; 12(1):1682895. PubMed ID: 31769727
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Intact quantitation of cysteine-conjugated antibody-drug conjugates using native mass spectrometry.
    Li Y; Wang Y; Shenoy VM; Niu S; Jenkins GJ; Sarvaiya H
    Rapid Commun Mass Spectrom; 2024 Aug; 38(15):e9774. PubMed ID: 38812280
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A single liquid chromatography-quadrupole time-of-flight mass spectrometric method for the quantification of total antibody, antibody-conjugated drug and free payload of antibody-drug conjugates.
    Byeon JJ; Park MH; Shin SH; Lee BI; Park Y; Choi J; Kim N; Kang Y; Shin YG
    Biomed Chromatogr; 2018 Jul; 32(7):e4229. PubMed ID: 29505175
    [TBL] [Abstract][Full Text] [Related]  

  • 31. State-of-the-Art Native Mass Spectrometry and Ion Mobility Methods to Monitor Homogeneous Site-Specific Antibody-Drug Conjugates Synthesis.
    Deslignière E; Ehkirch A; Duivelshof BL; Toftevall H; Sjögren J; Guillarme D; D'Atri V; Beck A; Hernandez-Alba O; Cianférani S
    Pharmaceuticals (Basel); 2021 May; 14(6):. PubMed ID: 34073805
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Drug-to-antibody determination for an antibody-drug-conjugate utilizing cathepsin B digestion coupled with reversed-phase high-pressure liquid chromatography analysis.
    Adamo M; Sun G; Qiu D; Valente J; Lan W; Song H; Bolgar M; Katiyar A; Krishnamurthy G
    J Chromatogr A; 2017 Jan; 1481():44-52. PubMed ID: 28017567
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Automated online deconjugation of antibody-drug conjugate for small molecule drug profiling.
    Thomas R; Song D; Pourmohamad T; Kurita K; Chin S; Dai L; Goyon A; Medley CD; Gruenhagen JA; Chen T
    J Chromatogr A; 2024 Jan; 1715():464575. PubMed ID: 38150875
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Middle-Down Multi-Attribute Analysis of Antibody-Drug Conjugates with Electron Transfer Dissociation.
    Chen B; Lin Z; Zhu Y; Jin Y; Larson E; Xu Q; Fu C; Zhang Z; Zhang Q; Pritts WA; Ge Y
    Anal Chem; 2019 Sep; 91(18):11661-11669. PubMed ID: 31442030
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Systematic LC/MS/MS Investigations for the IND-Enabling Extended Characterization of Antibody-Drug Conjugate Modifications.
    Linz T; Yeo D; Hong Q; Zmolek W; McFarland J; Barfield RM; Haskins WE; Rabuka D
    Antibodies (Basel); 2018 Nov; 7(4):. PubMed ID: 31544890
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Qualitative analysis of antibody-drug conjugates (ADCs): an experimental comparison of analytical techniques of cysteine-linked ADCs.
    Källsten M; Hartmann R; Artemenko K; Lind SB; Lehmann F; Bergquist J
    Analyst; 2018 Nov; 143(22):5487-5496. PubMed ID: 30289422
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Understanding How the Stability of the Thiol-Maleimide Linkage Impacts the Pharmacokinetics of Lysine-Linked Antibody-Maytansinoid Conjugates.
    Ponte JF; Sun X; Yoder NC; Fishkin N; Laleau R; Coccia J; Lanieri L; Bogalhas M; Wang L; Wilhelm S; Widdison W; Pinkas J; Keating TA; Chari R; Erickson HK; Lambert JM
    Bioconjug Chem; 2016 Jul; 27(7):1588-98. PubMed ID: 27174129
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Calculated conjugated payload from immunoassay and LC-MS intact protein analysis measurements of antibody-drug conjugate.
    Rago B; Clark T; King L; Zhang J; Tumey LN; Li F; Barletta F; Wei C; Leal M; Hansel S; Han X
    Bioanalysis; 2016 Nov; 8(21):2205-2217. PubMed ID: 27682846
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Investigation of low recovery in the free drug assay for antibody drug conjugates by size exclusion-reversed phase two dimensional-liquid chromatography.
    Li Y; Stella C; Zheng L; Bechtel C; Gruenhagen J; Jacobson F; Medley CD
    J Chromatogr B Analyt Technol Biomed Life Sci; 2016 Oct; 1032():112-118. PubMed ID: 27212187
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Universal Affinity Capture Liquid Chromatography-Mass Spectrometry Assay for Evaluation of Biotransformation of Site-Specific Antibody Drug Conjugates in Preclinical Studies.
    Kotapati S; Passmore D; Yamazoe S; Sanku RKK; Cong Q; Poudel YB; Chowdari NS; Gangwar S; Rao C; Rangan VS; Cardarelli PM; Deshpande S; Strop P; Dollinger G; Rajpal A
    Anal Chem; 2020 Jan; 92(2):2065-2073. PubMed ID: 31860282
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.