BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 26658610)

  • 1. Intrinsically active variants of Erk oncogenically transform cells and disclose unexpected autophosphorylation capability that is independent of TEY phosphorylation.
    Smorodinsky-Atias K; Goshen-Lago T; Goldberg-Carp A; Melamed D; Shir A; Mooshayef N; Beenstock J; Karamansha Y; Darlyuk-Saadon I; Livnah O; Ahn NG; Admon A; Engelberg D
    Mol Biol Cell; 2016 Mar; 27(6):1026-39. PubMed ID: 26658610
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Isolation of intrinsically active (MEK-independent) variants of the ERK family of mitogen-activated protein (MAP) kinases.
    Levin-Salomon V; Kogan K; Ahn NG; Livnah O; Engelberg D
    J Biol Chem; 2008 Dec; 283(50):34500-10. PubMed ID: 18829462
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Variants of the yeast MAPK Mpk1 are fully functional independently of activation loop phosphorylation.
    Goshen-Lago T; Goldberg-Carp A; Melamed D; Darlyuk-Saadon I; Bai C; Ahn NG; Admon A; Engelberg D
    Mol Biol Cell; 2016 Sep; 27(17):2771-83. PubMed ID: 27413009
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Active ERK2 is sufficient to mediate growth arrest and differentiation signaling.
    Wu PK; Hong SK; Yoon SH; Park JI
    FEBS J; 2015 Mar; 282(6):1017-30. PubMed ID: 25639353
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A conserved arginine within the αC-helix of Erk1/2 is a latch of autoactivation and of oncogenic capabilities.
    Soudah N; Baskin A; Smorodinsky-Atias K; Beenstock J; Ganon Y; Hayouka R; Aboraya M; Livnah O; Ilouz R; Engelberg D
    J Biol Chem; 2023 Sep; 299(9):105072. PubMed ID: 37474104
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Different effects of point mutations within the B-Raf glycine-rich loop in colorectal tumors on mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase and nuclear factor kappaB pathway and cellular transformation.
    Ikenoue T; Hikiba Y; Kanai F; Aragaki J; Tanaka Y; Imamura J; Imamura T; Ohta M; Ijichi H; Tateishi K; Kawakami T; Matsumura M; Kawabe T; Omata M
    Cancer Res; 2004 May; 64(10):3428-35. PubMed ID: 15150094
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutations That Confer Drug-Resistance, Oncogenicity and Intrinsic Activity on the ERK MAP Kinases-Current State of the Art.
    Smorodinsky-Atias K; Soudah N; Engelberg D
    Cells; 2020 Jan; 9(1):. PubMed ID: 31935908
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways.
    Rusyn EV; Reynolds ER; Shao H; Grana TM; Chan TO; Andres DA; Cox AD
    Oncogene; 2000 Sep; 19(41):4685-94. PubMed ID: 11032018
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting of magnolin on ERKs inhibits Ras/ERKs/RSK2-signaling-mediated neoplastic cell transformation.
    Lee CJ; Lee HS; Ryu HW; Lee MH; Lee JY; Li Y; Dong Z; Lee HK; Oh SR; Cho YY
    Carcinogenesis; 2014 Feb; 35(2):432-41. PubMed ID: 24031026
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Elevated levels of ornithine decarboxylase cooperate with Raf/ERK activation to convert normal keratinocytes into invasive malignant cells.
    Hayes CS; DeFeo K; Lan L; Paul B; Sell C; Gilmour SK
    Oncogene; 2006 Mar; 25(10):1543-53. PubMed ID: 16278677
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transfection of constitutively active mitogen-activated protein/extracellular signal-regulated kinase kinase confers tumorigenic and metastatic potentials to NIH3T3 cells.
    Welch DR; Sakamaki T; Pioquinto R; Leonard TO; Goldberg SF; Hon Q; Erikson RL; Rieber M; Rieber MS; Hicks DJ; Bonventre JV; Alessandrini A
    Cancer Res; 2000 Mar; 60(6):1552-6. PubMed ID: 10749122
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Two transforming C-RAF germ-line mutations identified in patients with therapy-related acute myeloid leukemia.
    Zebisch A; Staber PB; Delavar A; Bodner C; Hiden K; Fischereder K; Janakiraman M; Linkesch W; Auner HW; Emberger W; Windpassinger C; Schimek MG; Hoefler G; Troppmair J; Sill H
    Cancer Res; 2006 Apr; 66(7):3401-8. PubMed ID: 16585161
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Studies on cell signaling immunomodulated murine peritoneal suppressor macrophages: LPS and PMA mediate the activation of RAF-1, MAPK p44 and MAPK p42 and p38 MAPK].
    Chang ZL; Lin MQ; Wang MZ; Yao Z
    Shi Yan Sheng Wu Xue Bao; 1997 Mar; 30(1):73-81. PubMed ID: 10684111
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ras transformation of RIE-1 cells activates cap-independent translation of ornithine decarboxylase: regulation by the Raf/MEK/ERK and phosphatidylinositol 3-kinase pathways.
    Origanti S; Shantz LM
    Cancer Res; 2007 May; 67(10):4834-42. PubMed ID: 17510413
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RRM1 domain of the splicing oncoprotein SRSF1 is required for MEK1-MAPK-ERK activation and cellular transformation.
    Shimoni-Sebag A; Lebenthal-Loinger I; Zender L; Karni R
    Carcinogenesis; 2013 Nov; 34(11):2498-504. PubMed ID: 23843040
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lead acetate induces EGFR activation upstream of SFK and PKCalpha linkage to the Ras/Raf-1/ERK signaling.
    Wang CY; Wang YT; Tzeng DW; Yang JL
    Toxicol Appl Pharmacol; 2009 Mar; 235(2):244-52. PubMed ID: 19133285
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Depletion of ERK2 but not ERK1 abrogates oncogenic Ras-induced senescence.
    Shin J; Yang J; Lee JC; Baek KH
    Cell Signal; 2013 Dec; 25(12):2540-7. PubMed ID: 23993963
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional analysis of mutations within the kinase activation segment of B-Raf in human colorectal tumors.
    Ikenoue T; Hikiba Y; Kanai F; Tanaka Y; Imamura J; Imamura T; Ohta M; Ijichi H; Tateishi K; Kawakami T; Aragaki J; Matsumura M; Kawabe T; Omata M
    Cancer Res; 2003 Dec; 63(23):8132-7. PubMed ID: 14678966
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Radicicol suppresses transformation and restores tropomyosin-2 expression in both ras- and MEK-transformed cells without inhibiting the Raf/MEK/ERK signaling cascade.
    Kim PN; Jonasch E; Mosterman BC; Mier JW; Janssen RA
    Cell Growth Differ; 2001 Nov; 12(11):543-50. PubMed ID: 11714635
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Osteopontin is an oncogenic Vav1- but not wild-type Vav1-responsive gene: implications for fibroblast transformation.
    Schapira V; Lazer G; Katzav S
    Cancer Res; 2006 Jun; 66(12):6183-91. PubMed ID: 16778192
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.