These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

110 related articles for article (PubMed ID: 26661504)

  • 1. Solution-State (17)O Quadrupole Central-Transition NMR Spectroscopy in the Active Site of Tryptophan Synthase.
    Young RP; Caulkins BG; Borchardt D; Bulloch DN; Larive CK; Dunn MF; Mueller LJ
    Angew Chem Int Ed Engl; 2016 Jan; 55(4):1350-4. PubMed ID: 26661504
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Imaging active site chemistry and protonation states: NMR crystallography of the tryptophan synthase α-aminoacrylate intermediate.
    Holmes JB; Liu V; Caulkins BG; Hilario E; Ghosh RK; Drago VN; Young RP; Romero JA; Gill AD; Bogie PM; Paulino J; Wang X; Riviere G; Bosken YK; Struppe J; Hassan A; Guidoulianov J; Perrone B; Mentink-Vigier F; Chang CA; Long JR; Hooley RJ; Mueser TC; Dunn MF; Mueller LJ
    Proc Natl Acad Sci U S A; 2022 Jan; 119(2):. PubMed ID: 34996869
    [TBL] [Abstract][Full Text] [Related]  

  • 3. X-ray and NMR crystallography in an enzyme active site: the indoline quinonoid intermediate in tryptophan synthase.
    Lai J; Niks D; Wang Y; Domratcheva T; Barends TR; Schwarz F; Olsen RA; Elliott DW; Fatmi MQ; Chang CE; Schlichting I; Dunn MF; Mueller LJ
    J Am Chem Soc; 2011 Jan; 133(1):4-7. PubMed ID: 21142052
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NMR crystallography of enzyme active sites: probing chemically detailed, three-dimensional structure in tryptophan synthase.
    Mueller LJ; Dunn MF
    Acc Chem Res; 2013 Sep; 46(9):2008-17. PubMed ID: 23537227
    [TBL] [Abstract][Full Text] [Related]  

  • 5. NMR Crystallography of a Carbanionic Intermediate in Tryptophan Synthase: Chemical Structure, Tautomerization, and Reaction Specificity.
    Caulkins BG; Young RP; Kudla RA; Yang C; Bittbauer TJ; Bastin B; Hilario E; Fan L; Marsella MJ; Dunn MF; Mueller LJ
    J Am Chem Soc; 2016 Nov; 138(46):15214-15226. PubMed ID: 27779384
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Plasticity of the tryptophan synthase active site probed by 31P NMR spectroscopy.
    Schnackerz KD; Mozzarelli A
    J Biol Chem; 1998 Dec; 273(50):33247-53. PubMed ID: 9837895
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Catalytic roles of βLys87 in tryptophan synthase: (15)N solid state NMR studies.
    Caulkins BG; Yang C; Hilario E; Fan L; Dunn MF; Mueller LJ
    Biochim Biophys Acta; 2015 Sep; 1854(9):1194-9. PubMed ID: 25688830
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of pH and monovalent cations on the formation of quinonoid intermediates of the tryptophan synthase alpha(2)beta(2) complex in solution and in the crystal.
    Mozzarelli A; Peracchi A; Rovegno B; Dalè G; Rossi GL; Dunn MF
    J Biol Chem; 2000 Mar; 275(10):6956-62. PubMed ID: 10702257
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protonation states and catalysis: Molecular dynamics studies of intermediates in tryptophan synthase.
    Huang YM; You W; Caulkins BG; Dunn MF; Mueller LJ; Chang CE
    Protein Sci; 2016 Jan; 25(1):166-83. PubMed ID: 26013176
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stereospecificity of alpha-proton exchange reactions catalysed by pyridoxal-5'-phosphate-dependent enzymes.
    Malthouse JP
    Biochim Biophys Acta; 2003 Apr; 1647(1-2):138-42. PubMed ID: 12686123
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Atomic-resolution chemical characterization of (2x)72-kDa tryptophan synthase via four- and five-dimensional
    Klein A; Rovó P; Sakhrani VV; Wang Y; Holmes JB; Liu V; Skowronek P; Kukuk L; Vasa SK; Güntert P; Mueller LJ; Linser R
    Proc Natl Acad Sci U S A; 2022 Jan; 119(4):. PubMed ID: 35058365
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of aminoacrylate intermediates of pyridoxal-5'-phosphate dependent enzymes.
    Phillips RS; Bauer O
    Methods Enzymol; 2023; 685():199-224. PubMed ID: 37245902
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intermediate trapping via a conformational switch in the Na(+)-activated tryptophan synthase bienzyme complex.
    Harris RM; Dunn MF
    Biochemistry; 2002 Aug; 41(31):9982-90. PubMed ID: 12146962
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synergistic effects on escape of a ligand from the closed tryptophan synthase bienzyme complex.
    Harris RM; Ngo H; Dunn MF
    Biochemistry; 2005 Dec; 44(51):16886-95. PubMed ID: 16363802
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stereoelectronic control of bond formation in Escherichia coli tryptophan synthase: substrate specificity and enzymatic synthesis of the novel amino acid dihydroisotryptophan.
    Roy M; Keblawi S; Dunn MF
    Biochemistry; 1988 Sep; 27(18):6698-704. PubMed ID: 3058204
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protonation states of the tryptophan synthase internal aldimine active site from solid-state NMR spectroscopy: direct observation of the protonated Schiff base linkage to pyridoxal-5'-phosphate.
    Caulkins BG; Bastin B; Yang C; Neubauer TJ; Young RP; Hilario E; Huang YM; Chang CE; Fan L; Dunn MF; Marsella MJ; Mueller LJ
    J Am Chem Soc; 2014 Sep; 136(37):12824-7. PubMed ID: 25148001
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The reaction of indole with the aminoacrylate intermediate of Salmonella typhimurium tryptophan synthase: observation of a primary kinetic isotope effect with 3-[(2)H]indole.
    Cash MT; Miles EW; Phillips RS
    Arch Biochem Biophys; 2004 Dec; 432(2):233-43. PubMed ID: 15542062
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Severing of a hydrogen bond disrupts amino acid networks in the catalytically active state of the alpha subunit of tryptophan synthase.
    Axe JM; O'Rourke KF; Kerstetter NE; Yezdimer EM; Chan YM; Chasin A; Boehr DD
    Protein Sci; 2015 Apr; 24(4):484-94. PubMed ID: 25377949
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of the structural determinants for the stability of substrate and aminoacrylate external Schiff bases in O-acetylserine sulfhydrylase-A.
    Tian H; Guan R; Salsi E; Campanini B; Bettati S; Kumar VP; Karsten WE; Mozzarelli A; Cook PF
    Biochemistry; 2010 Jul; 49(29):6093-103. PubMed ID: 20550197
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Loop closure and intersubunit communication in tryptophan synthase.
    Schneider TR; Gerhardt E; Lee M; Liang PH; Anderson KS; Schlichting I
    Biochemistry; 1998 Apr; 37(16):5394-406. PubMed ID: 9548921
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.