BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 26668309)

  • 1. A Novel Naphthalimide Compound Restores p53 Function in Non-small Cell Lung Cancer by Reorganizing the Bak·Bcl-xl Complex and Triggering Transcriptional Regulation.
    Zhang G; An Y; Lu X; Zhong H; Zhu Y; Wu Y; Ma F; Yang J; Liu Y; Zhou Z; Peng Y; Chen Z
    J Biol Chem; 2016 Feb; 291(8):4211-25. PubMed ID: 26668309
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phthalazino[1,2-b]quinazolinones as p53 Activators: Cell Cycle Arrest, Apoptotic Response and Bak-Bcl-xl Complex Reorganization in Bladder Cancer Cells.
    Zhang GH; Yuan JM; Qian G; Gu CX; Wei K; Mo DL; Qin JK; Peng Y; Zhou ZP; Pan CX; Su GF
    J Med Chem; 2017 Aug; 60(16):6853-6866. PubMed ID: 28745887
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cisplatin-induced apoptosis in non-small-cell lung cancer cells is dependent on Bax- and Bak-induction pathway and synergistically activated by BH3-mimetic ABT-263 in p53 wild-type and mutant cells.
    Matsumoto M; Nakajima W; Seike M; Gemma A; Tanaka N
    Biochem Biophys Res Commun; 2016 Apr; 473(2):490-6. PubMed ID: 26996126
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Therapeutic restoring p53 function with small molecule for oncogene-driven non-small cell lung cancer by targeting serine 392 phosphorylation.
    Li L; Li P; Ma X; Zeng S; Peng Y; Zhang G
    Biochem Pharmacol; 2022 Sep; 203():115188. PubMed ID: 35902040
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitochondrial inhibitor sensitizes non-small-cell lung carcinoma cells to TRAIL-induced apoptosis by reactive oxygen species and Bcl-X(L)/p53-mediated amplification mechanisms.
    Shi YL; Feng S; Chen W; Hua ZC; Bian JJ; Yin W
    Cell Death Dis; 2014 Dec; 5(12):e1579. PubMed ID: 25522273
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutant p53 confers chemoresistance in non-small cell lung cancer by upregulating Nrf2.
    Tung MC; Lin PL; Wang YC; He TY; Lee MC; Yeh SD; Chen CY; Lee H
    Oncotarget; 2015 Dec; 6(39):41692-705. PubMed ID: 26497680
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tumor suppressor protein p53 promotes 2-methoxyestradiol-induced activation of Bak and Bax, leading to mitochondria-dependent apoptosis in human colon cancer HCT116 cells.
    Lee JY; Jee SB; Park WY; Choi YJ; Kim B; Kim YH; Jun do Y; Kim YH
    J Microbiol Biotechnol; 2014 Dec; 24(12):1654-63. PubMed ID: 25179905
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis.
    Nieminen AI; Eskelinen VM; Haikala HM; Tervonen TA; Yan Y; Partanen JI; Klefström J
    Proc Natl Acad Sci U S A; 2013 May; 110(20):E1839-48. PubMed ID: 23589839
    [TBL] [Abstract][Full Text] [Related]  

  • 9. G1 phase cell cycle arrest in NSCLC in response to LZ-106, an analog of enoxacin, is orchestrated through ROS overproduction in a P53-dependent manner.
    Yang L; Zhou J; Meng F; Fu C; Zou X; Liu J; Zhang C; Tan R; Li Z; Guo Q; Wei L
    Carcinogenesis; 2019 Mar; 40(1):131-144. PubMed ID: 30239617
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
    Zhang J; Huang K; O'Neill KL; Pang X; Luo X
    Cell Death Dis; 2016 Jun; 7(6):e2266. PubMed ID: 27310874
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Small-molecule MX-C2/3 suppresses non-small cell lung cancer progression via p53 activation.
    Li L; Du W; Wang H; Zhao Y; Huang Z; Peng Y; Zeng S; Zhang G
    Chem Biol Interact; 2022 Oct; 366():110142. PubMed ID: 36058261
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Individual dose and scheduling determine the efficacy of combining cytotoxic anticancer agents with a kinase inhibitor in non-small-cell lung cancer.
    Meiler J; Guyot M; Hoffarth S; Wesarg E; Höhn Y; Breitenbuecher F; Schuler M
    J Cancer Res Clin Oncol; 2012 Aug; 138(8):1385-94. PubMed ID: 22488173
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Silibilin-induces apoptosis in breast cancer cells by modulating p53, p21, Bak and Bcl-XL pathways.
    Pirouzpanah MB; Sabzichi M; Pirouzpanah S; Chavoshi H; Samadi N
    Asian Pac J Cancer Prev; 2015; 16(5):2087-92. PubMed ID: 25773855
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sesamin suppresses NSCLC cell proliferation and induces apoptosis via Akt/p53 pathway.
    Chen Y; Li H; Zhang W; Qi W; Lu C; Huang H; Yang Z; Liu B; Zhang L
    Toxicol Appl Pharmacol; 2020 Jan; 387():114848. PubMed ID: 31809756
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rhizoma Paridis Saponins Induces Cell Cycle Arrest and Apoptosis in Non-Small Cell Lung Carcinoma A549 Cells.
    Zhang J; Yang Y; Lei L; Tian M
    Med Sci Monit; 2015 Aug; 21():2535-41. PubMed ID: 26311066
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Immunohistochemical assessment of apoptosis-associated proteins: p53, Bcl-xL, Bax and Bak in gastric cancer cells in correlation with clinical and pathomorphological factors.
    Gryko M; Pryczynicz A; Guzińska-Ustymowicz K; Kamocki Z; Zaręba K; Kemona A; Kędra B
    Adv Med Sci; 2012 Jun; 57(1):77-83. PubMed ID: 22440942
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Radiosensitization of NSCLC cells by EGFR inhibition is the result of an enhanced p53-dependent G1 arrest.
    Kriegs M; Gurtner K; Can Y; Brammer I; Rieckmann T; Oertel R; Wysocki M; Dorniok F; Gal A; Grob TJ; Laban S; Kasten-Pisula U; Petersen C; Baumann M; Krause M; Dikomey E
    Radiother Oncol; 2015 Apr; 115(1):120-7. PubMed ID: 25796091
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Defects in apoptotic signal transduction in cisplatin-resistant non-small cell lung cancer cells.
    Ikuta K; Takemura K; Kihara M; Naito S; Lee E; Shimizu E; Yamauchi A
    Oncol Rep; 2005 Jun; 13(6):1229-34. PubMed ID: 15870947
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro study of the Polo-like kinase 1 inhibitor volasertib in non-small-cell lung cancer reveals a role for the tumor suppressor p53.
    Van den Bossche J; Deben C; De Pauw I; Lambrechts H; Hermans C; Deschoolmeester V; Jacobs J; Specenier P; Pauwels P; Vermorken JB; Peeters M; Lardon F; Wouters A
    Mol Oncol; 2019 May; 13(5):1196-1213. PubMed ID: 30859681
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel compound PS-101 exhibits selective inhibition in non-small-cell lung cancer cell by blocking the EGFR-driven antiapoptotic pathway.
    Zhang GH; Cai LJ; Wang YF; Zhou YH; An YF; Liu YC; Peng Y; Chen ZF; Liang H
    Biochem Pharmacol; 2013 Dec; 86(12):1721-30. PubMed ID: 24161785
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.