136 related articles for article (PubMed ID: 26675211)
1. 5'-C-Malonyl RNA: Small Interfering RNAs Modified with 5'-Monophosphate Bioisostere Demonstrate Gene Silencing Activity.
Zlatev I; Foster DJ; Liu J; Charisse K; Brigham B; Parmar RG; Jadhav V; Maier MA; Rajeev KG; Egli M; Manoharan M
ACS Chem Biol; 2016 Apr; 11(4):953-60. PubMed ID: 26675211
[TBL] [Abstract][Full Text] [Related]
2. 5'-(E)-Vinylphosphonate: A Stable Phosphate Mimic Can Improve the RNAi Activity of siRNA-GalNAc Conjugates.
Parmar R; Willoughby JL; Liu J; Foster DJ; Brigham B; Theile CS; Charisse K; Akinc A; Guidry E; Pei Y; Strapps W; Cancilla M; Stanton MG; Rajeev KG; Sepp-Lorenzino L; Manoharan M; Meyers R; Maier MA; Jadhav V
Chembiochem; 2016 Jun; 17(11):985-9. PubMed ID: 27121751
[TBL] [Abstract][Full Text] [Related]
3. Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.
Harborth J; Elbashir SM; Vandenburgh K; Manninga H; Scaringe SA; Weber K; Tuschl T
Antisense Nucleic Acid Drug Dev; 2003 Apr; 13(2):83-105. PubMed ID: 12804036
[TBL] [Abstract][Full Text] [Related]
4. Isonucleotide incorporation into middle and terminal siRNA duplexes exhibits high gene silencing efficacy and nuclease resistance.
Ma Y; Liu S; Wang Y; Zhao Y; Huang Y; Zhong L; Guan Z; Zhang L; Yang Z
Org Biomol Chem; 2017 Jun; 15(24):5161-5170. PubMed ID: 28585968
[TBL] [Abstract][Full Text] [Related]
5. Effects of conformational alteration induced by D-/L-isonucleoside incorporation in siRNA on their stability in serum and silencing activity.
Huang Y; Chen Z; Chen Y; Zhang H; Zhang Y; Zhao Y; Yang Z; Zhang L
Bioconjug Chem; 2013 Jun; 24(6):951-9. PubMed ID: 23682837
[TBL] [Abstract][Full Text] [Related]
6. Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3'-ends of siRNAs.
Hamada M; Ohtsuka T; Kawaida R; Koizumi M; Morita K; Furukawa H; Imanishi T; Miyagishi M; Taira K
Antisense Nucleic Acid Drug Dev; 2002 Oct; 12(5):301-9. PubMed ID: 12477280
[TBL] [Abstract][Full Text] [Related]
7. Single-Stranded Silencing RNAs: Hit Rate and Chemical Modification.
Pendergraff HM; Debacker AJ; Watts JK
Nucleic Acid Ther; 2016 Aug; 26(4):216-22. PubMed ID: 27123752
[TBL] [Abstract][Full Text] [Related]
8. RNA helicase A is not required for RISC activity.
Liang XH; Crooke ST
Biochim Biophys Acta; 2013 Oct; 1829(10):1092-101. PubMed ID: 23895878
[TBL] [Abstract][Full Text] [Related]
9. Single modification at position 14 of siRNA strand abolishes its gene-silencing activity by decreasing both RISC loading and target degradation.
Zheng J; Zhang L; Zhang J; Wang X; Ye K; Xi Z; Du Q; Liang Z
FASEB J; 2013 Oct; 27(10):4017-26. PubMed ID: 23771927
[TBL] [Abstract][Full Text] [Related]
10. Effective gene silencing activity of prodrug-type 2'-O-methyldithiomethyl siRNA compared with non-prodrug-type 2'-O-methyl siRNA.
Hayashi J; Nishigaki M; Ochi Y; Wada SI; Wada F; Nakagawa O; Obika S; Harada-Shiba M; Urata H
Bioorg Med Chem Lett; 2018 Jul; 28(12):2171-2174. PubMed ID: 29764744
[TBL] [Abstract][Full Text] [Related]
11. Synthesis, gene silencing, and molecular modeling studies of 4'-C-aminomethyl-2'-O-methyl modified small interfering RNAs.
Gore KR; Nawale GN; Harikrishna S; Chittoor VG; Pandey SK; Höbartner C; Patankar S; Pradeepkumar PI
J Org Chem; 2012 Apr; 77(7):3233-45. PubMed ID: 22372696
[TBL] [Abstract][Full Text] [Related]
12. Silencing activity of 2'-O-methyl modified anti-MDR1 siRNAs with mismatches in the central part of the duplexes.
Petrova NS; Meschaninova MI; Venyaminova AG; Zenkova MA; Vlassov VV; Chernolovskaya EL
FEBS Lett; 2011 Jul; 585(14):2352-6. PubMed ID: 21704032
[TBL] [Abstract][Full Text] [Related]
13. Single-stranded antisense siRNAs guide target RNA cleavage in RNAi.
Martinez J; Patkaniowska A; Urlaub H; Lührmann R; Tuschl T
Cell; 2002 Sep; 110(5):563-74. PubMed ID: 12230974
[TBL] [Abstract][Full Text] [Related]
14. 2'-O-methyl-modified anti-MDR1 fork-siRNA duplexes exhibiting high nuclease resistance and prolonged silencing activity.
Petrova Kruglova NS; Meschaninova MI; Venyaminova AG; Zenkova MA; Vlassov VV; Chernolovskaya EL
Oligonucleotides; 2010 Dec; 20(6):297-308. PubMed ID: 21028964
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of hepatitis B virus replication in cultured cells and in vivo using 2'-O-guanidinopropyl modified siRNAs.
Marimani MD; Ely A; Buff MC; Bernhardt S; Engels JW; Arbuthnot P
Bioorg Med Chem; 2013 Oct; 21(20):6145-55. PubMed ID: 23743442
[TBL] [Abstract][Full Text] [Related]
16. 5΄-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo.
Haraszti RA; Roux L; Coles AH; Turanov AA; Alterman JF; Echeverria D; Godinho BMDC; Aronin N; Khvorova A
Nucleic Acids Res; 2017 Jul; 45(13):7581-7592. PubMed ID: 28591791
[TBL] [Abstract][Full Text] [Related]
17. Competition for RISC binding predicts in vitro potency of siRNA.
Koller E; Propp S; Murray H; Lima W; Bhat B; Prakash TP; Allerson CR; Swayze EE; Marcusson EG; Dean NM
Nucleic Acids Res; 2006; 34(16):4467-76. PubMed ID: 16945958
[TBL] [Abstract][Full Text] [Related]
18. Competition potency of siRNA is specified by the 5'-half sequence of the guide strand.
Yoo JW; Kim S; Lee DK
Biochem Biophys Res Commun; 2008 Feb; 367(1):78-83. PubMed ID: 18164261
[TBL] [Abstract][Full Text] [Related]
19. The human RNA kinase hClp1 is active on 3' transfer RNA exons and short interfering RNAs.
Weitzer S; Martinez J
Nature; 2007 May; 447(7141):222-6. PubMed ID: 17495927
[TBL] [Abstract][Full Text] [Related]
20. Palmitic acid-conjugated 21-nucleotide siRNA enhances gene-silencing activity.
Kubo T; Yanagihara K; Takei Y; Mihara K; Morita Y; Seyama T
Mol Pharm; 2011 Dec; 8(6):2193-203. PubMed ID: 21985606
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
