BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

264 related articles for article (PubMed ID: 26675378)

  • 1. Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors.
    Duarte-Pereira S; Pereira-Castro I; Silva SS; Correia MG; Neto C; da Costa LT; Amorim A; Silva RM
    Oncotarget; 2016 Jan; 7(2):1973-83. PubMed ID: 26675378
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NAD Synthesis Pathway Interference Is a Viable Therapeutic Strategy for Chondrosarcoma.
    Peterse EFP; van den Akker BEWM; Niessen B; Oosting J; Suijker J; de Jong Y; Danen EHJ; Cleton-Jansen AM; Bovée JVMG
    Mol Cancer Res; 2017 Dec; 15(12):1714-1721. PubMed ID: 28860121
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression patterns of nicotinamide phosphoribosyltransferase and nicotinic acid phosphoribosyltransferase in human malignant lymphomas.
    Olesen UH; Hastrup N; Sehested M
    APMIS; 2011 Apr; 119(4-5):296-303. PubMed ID: 21492230
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Supplementation of nicotinic acid with NAMPT inhibitors results in loss of in vivo efficacy in NAPRT1-deficient tumor models.
    O'Brien T; Oeh J; Xiao Y; Liang X; Vanderbilt A; Qin A; Yang L; Lee LB; Ly J; Cosino E; LaCap JA; Ogasawara A; Williams S; Nannini M; Liederer BM; Jackson P; Dragovich PS; Sampath D
    Neoplasia; 2013 Dec; 15(12):1314-29. PubMed ID: 24403854
    [TBL] [Abstract][Full Text] [Related]  

  • 5. NAMPT and NAPRT, Key Enzymes in NAD Salvage Synthesis Pathway, Are of Negative Prognostic Value in Colorectal Cancer.
    Li XQ; Lei J; Mao LH; Wang QL; Xu F; Ran T; Zhou ZH; He S
    Front Oncol; 2019; 9():736. PubMed ID: 31448236
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair.
    Piacente F; Caffa I; Ravera S; Sociali G; Passalacqua M; Vellone VG; Becherini P; Reverberi D; Monacelli F; Ballestrero A; Odetti P; Cagnetta A; Cea M; Nahimana A; Duchosal M; Bruzzone S; Nencioni A
    Cancer Res; 2017 Jul; 77(14):3857-3869. PubMed ID: 28507103
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Versatile Continuous Fluorometric Enzymatic Assay for Targeting Nicotinate Phosphoribosyltransferase.
    Minazzato G; Marangoni E; Fortunato C; Petrelli R; Cappellacci L; Del Bello F; Sorci L; Gasparrini M; Piacente F; Bruzzone S; Raffaelli N
    Molecules; 2023 Jan; 28(3):. PubMed ID: 36770640
    [TBL] [Abstract][Full Text] [Related]  

  • 8. NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling.
    Chowdhry S; Zanca C; Rajkumar U; Koga T; Diao Y; Raviram R; Liu F; Turner K; Yang H; Brunk E; Bi J; Furnari F; Bafna V; Ren B; Mischel PS
    Nature; 2019 May; 569(7757):570-575. PubMed ID: 31019297
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NAMPT and NAPRT1: novel polymorphisms and distribution of variants between normal tissues and tumor samples.
    Duarte-Pereira S; Silva SS; Azevedo L; Castro L; Amorim A; Silva RM
    Sci Rep; 2014 Sep; 4():6311. PubMed ID: 25201160
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Properly Substituted Benzimidazoles as a New Promising Class of Nicotinate Phosphoribosyltransferase (NAPRT) Modulators.
    Baldassarri C; Giorgioni G; Piergentili A; Quaglia W; Fontana S; Mammoli V; Minazzato G; Marangoni E; Gasparrini M; Sorci L; Raffaelli N; Cappellacci L; Petrelli R; Del Bello F
    Pharmaceuticals (Basel); 2023 Jan; 16(2):. PubMed ID: 37259338
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Loss of NAPRT1 expression by tumor-specific promoter methylation provides a novel predictive biomarker for NAMPT inhibitors.
    Shames DS; Elkins K; Walter K; Holcomb T; Du P; Mohl D; Xiao Y; Pham T; Haverty PM; Liederer B; Liang X; Yauch RL; O'Brien T; Bourgon R; Koeppen H; Belmont LD
    Clin Cancer Res; 2013 Dec; 19(24):6912-23. PubMed ID: 24097869
    [TBL] [Abstract][Full Text] [Related]  

  • 12.
    Duarte-Pereira S; Fajarda O; Matos S; Luís Oliveira J; Silva RM
    Genes (Basel); 2021 Dec; 12(12):. PubMed ID: 34946971
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selective Cytotoxicity of the NAMPT Inhibitor FK866 Toward Gastric Cancer Cells With Markers of the Epithelial-Mesenchymal Transition, Due to Loss of NAPRT.
    Lee J; Kim H; Lee JE; Shin SJ; Oh S; Kwon G; Kim H; Choi YY; White MA; Paik S; Cheong JH; Kim HS
    Gastroenterology; 2018 Sep; 155(3):799-814.e13. PubMed ID: 29775598
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of a novel NAMPT inhibitor that selectively targets NAPRT-deficient EMT-subtype cancer cells and alleviates chemotherapy-induced peripheral neuropathy.
    Kim M; Kim H; Kang BG; Lee J; Kim T; Lee H; Jung J; Oh MJ; Seo S; Ryu MJ; Sung Y; Lee Y; Yeom J; Han G; Cha SS; Jung H; Kim HS
    Theranostics; 2023; 13(14):5075-5098. PubMed ID: 37771778
    [No Abstract]   [Full Text] [Related]  

  • 15. Retinal toxicity, in vivo and in vitro, associated with inhibition of nicotinamide phosphoribosyltransferase.
    Zabka TS; Singh J; Dhawan P; Liederer BM; Oeh J; Kauss MA; Xiao Y; Zak M; Lin T; McCray B; La N; Nguyen T; Beyer J; Farman C; Uppal H; Dragovich PS; O'Brien T; Sampath D; Misner DL
    Toxicol Sci; 2015 Mar; 144(1):163-72. PubMed ID: 25505128
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibitors of NAD
    Ghanem MS; Caffa I; Monacelli F; Nencioni A
    Int J Mol Sci; 2024 Feb; 25(4):. PubMed ID: 38396769
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting the NAD Salvage Synthesis Pathway as a Novel Therapeutic Strategy for Osteosarcomas with Low NAPRT Expression.
    Franceschini N; Oosting J; Tamsma M; Niessen B; Bruijn IB; van den Akker B; Kruisselbrink AB; Palubeckaitė I; Bovée JVMG; Cleton-Jansen AM
    Int J Mol Sci; 2021 Jun; 22(12):. PubMed ID: 34200964
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nicotinamide phosphoribosyltransferase can affect metastatic activity and cell adhesive functions by regulating integrins in breast cancer.
    Santidrian AF; LeBoeuf SE; Wold ED; Ritland M; Forsyth JS; Felding BH
    DNA Repair (Amst); 2014 Nov; 23():79-87. PubMed ID: 25263164
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma.
    Fons NR; Sundaram RK; Breuer GA; Peng S; McLean RL; Kalathil AN; Schmidt MS; Carvalho DM; Mackay A; Jones C; Carcaboso ÁM; Nazarian J; Berens ME; Brenner C; Bindra RS
    Nat Commun; 2019 Aug; 10(1):3790. PubMed ID: 31439867
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NAPRT, but Not NAMPT, Provides Additional Support for NAD Synthesis in Esophageal Precancerous Lesions.
    Wang N; Pan D; Wang X; Su M; Wang X; Yan Q; Sun G; Wang S
    Nutrients; 2022 Nov; 14(22):. PubMed ID: 36432602
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.