575 related articles for article (PubMed ID: 26678016)
1. Attenuated presenilin-1 endoproteolysis enhances store-operated calcium currents in neuronal cells.
Ryazantseva M; Skobeleva K; Glushankova L; Kaznacheyeva E
J Neurochem; 2016 Mar; 136(5):1085-95. PubMed ID: 26678016
[TBL] [Abstract][Full Text] [Related]
2. Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease.
Honarnejad K; Jung CK; Lammich S; Arzberger T; Kretzschmar H; Herms J
J Cell Mol Med; 2013 Feb; 17(2):293-302. PubMed ID: 23379308
[TBL] [Abstract][Full Text] [Related]
3. G206D Mutation of Presenilin-1 Reduces Pen2 Interaction, Increases Aβ42/Aβ40 Ratio and Elevates ER Ca(2+) Accumulation.
Chen WT; Hsieh YF; Huang YJ; Lin CC; Lin YT; Liu YC; Lien CC; Cheng IH
Mol Neurobiol; 2015 Dec; 52(3):1835-1849. PubMed ID: 25394380
[TBL] [Abstract][Full Text] [Related]
4. Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels.
Zatti G; Burgo A; Giacomello M; Barbiero L; Ghidoni R; Sinigaglia G; Florean C; Bagnoli S; Binetti G; Sorbi S; Pizzo P; Fasolato C
Cell Calcium; 2006 Jun; 39(6):539-50. PubMed ID: 16620965
[TBL] [Abstract][Full Text] [Related]
5. Familial Alzheimer's disease-associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca2+ entry.
Tong BC; Lee CS; Cheng WH; Lai KO; Foskett JK; Cheung KH
Sci Signal; 2016 Sep; 9(444):ra89. PubMed ID: 27601731
[TBL] [Abstract][Full Text] [Related]
6. Presenilin-1 Delta E9 Mutant Induces STIM1-Driven Store-Operated Calcium Channel Hyperactivation in Hippocampal Neurons.
Ryazantseva M; Goncharova A; Skobeleva K; Erokhin M; Methner A; Georgiev P; Kaznacheyeva E
Mol Neurobiol; 2018 Jun; 55(6):4667-4680. PubMed ID: 28707074
[TBL] [Abstract][Full Text] [Related]
7. Three-amino acid spacing of presenilin endoproteolysis suggests a general stepwise cleavage of gamma-secretase-mediated intramembrane proteolysis.
Fukumori A; Fluhrer R; Steiner H; Haass C
J Neurosci; 2010 Jun; 30(23):7853-62. PubMed ID: 20534834
[TBL] [Abstract][Full Text] [Related]
8. Thapsigargin affects presenilin-2 but not presenilin-1 regulation in SK-N-BE cells.
Rivabene R; Visentin S; Piscopo P; De Nuccio C; Crestini A; Svetoni F; Rosa P; Confaloni A
Exp Biol Med (Maywood); 2014 Feb; 239(2):213-24. PubMed ID: 24363250
[TBL] [Abstract][Full Text] [Related]
9. Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations.
Tu H; Nelson O; Bezprozvanny A; Wang Z; Lee SF; Hao YH; Serneels L; De Strooper B; Yu G; Bezprozvanny I
Cell; 2006 Sep; 126(5):981-93. PubMed ID: 16959576
[TBL] [Abstract][Full Text] [Related]
10. Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis.
Islam S; Sun Y; Gao Y; Nakamura T; Noorani AA; Li T; Wong PC; Kimura N; Matsubara E; Kasuga K; Ikeuchi T; Tomita T; Zou K; Michikawa M
J Neurosci; 2022 Feb; 42(8):1574-1586. PubMed ID: 34987110
[TBL] [Abstract][Full Text] [Related]
11. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
Xia W; Zhang J; Ostaszewski BL; Kimberly WT; Seubert P; Koo EH; Shen J; Selkoe DJ
Biochemistry; 1998 Nov; 37(47):16465-71. PubMed ID: 9843412
[TBL] [Abstract][Full Text] [Related]
12. Familial Alzheimer's disease-linked presenilin-1 mutation M146V affects store-operated calcium entry: does gain look like loss?
Ryazantseva M; Skobeleva K; Kaznacheyeva E
Biochimie; 2013 Jul; 95(7):1506-9. PubMed ID: 23624206
[TBL] [Abstract][Full Text] [Related]
13. Different transmembrane domains determine the specificity and efficiency of the cleavage activity of the γ-secretase subunit presenilin.
Schmidt FC; Fitz K; Feilen LP; Okochi M; Steiner H; Langosch D
J Biol Chem; 2023 May; 299(5):104626. PubMed ID: 36944398
[TBL] [Abstract][Full Text] [Related]
14. Conformational Models of APP Processing by Gamma Secretase Based on Analysis of Pathogenic Mutations.
Kim M; Bezprozvanny I
Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34948396
[TBL] [Abstract][Full Text] [Related]
15. Intracellular Calcium Dysregulation by the Alzheimer's Disease-Linked Protein Presenilin 2.
Galla L; Redolfi N; Pozzan T; Pizzo P; Greotti E
Int J Mol Sci; 2020 Jan; 21(3):. PubMed ID: 31991578
[TBL] [Abstract][Full Text] [Related]
16. Repression of transcription of presenilin-1 inhibits γ-secretase independent ER Ca²⁺ leak that is impaired by FAD mutations.
Das HK; Tchedre K; Mueller B
J Neurochem; 2012 Aug; 122(3):487-500. PubMed ID: 22607268
[TBL] [Abstract][Full Text] [Related]
17. Quantitative comparison of presenilin protein expression reveals greater activity of PS2-γ-secretase.
Eccles MK; Main N; Carlessi R; Armstrong AM; Sabale M; Roberts-Mok B; Tirnitz-Parker JEE; Agostino M; Groth D; Fraser PE; Verdile G
FASEB J; 2024 Jan; 38(1):e23396. PubMed ID: 38156414
[TBL] [Abstract][Full Text] [Related]
18. Pathological activity of familial Alzheimer's disease-associated mutant presenilin can be executed by six different gamma-secretase complexes.
Shirotani K; Tomioka M; Kremmer E; Haass C; Steiner H
Neurobiol Dis; 2007 Jul; 27(1):102-7. PubMed ID: 17560791
[TBL] [Abstract][Full Text] [Related]
19. Is Alzheimer's disease a disorder of mitochondria-associated membranes?
Schon EA; Area-Gomez E
J Alzheimers Dis; 2010; 20 Suppl 2():S281-92. PubMed ID: 20421691
[TBL] [Abstract][Full Text] [Related]
20. Familial Alzheimer's disease-linked presenilin mutants and intracellular Ca
Greotti E; Capitanio P; Wong A; Pozzan T; Pizzo P; Pendin D
Cell Calcium; 2019 May; 79():44-56. PubMed ID: 30822648
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
