These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 26679806)

  • 1. Feline hepatic biotransformation of diazepam: Differences between cats and dogs.
    van Beusekom CD; van den Heuvel JJ; Koenderink JB; Russel FG; Schrickx JA
    Res Vet Sci; 2015 Dec; 103():119-25. PubMed ID: 26679806
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The feline bile salt export pump: a structural and functional comparison with canine and human Bsep/BSEP.
    van Beusekom CD; van den Heuvel JJ; Koenderink JB; Schrickx JA; Russel FG
    BMC Vet Res; 2013 Dec; 9():259. PubMed ID: 24359682
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro model systems to investigate bile salt export pump (BSEP) activity and drug interactions: A review.
    Cheng Y; Woolf TF; Gan J; He K
    Chem Biol Interact; 2016 Aug; 255():23-30. PubMed ID: 26683212
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of bile salt transport by drugs associated with liver injury in primary hepatocytes from human, monkey, dog, rat, and mouse.
    Zhang J; He K; Cai L; Chen YC; Yang Y; Shi Q; Woolf TF; Ge W; Guo L; Borlak J; Tong W
    Chem Biol Interact; 2016 Aug; 255():45-54. PubMed ID: 27000539
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cholestatic potential of troglitazone as a possible factor contributing to troglitazone-induced hepatotoxicity: in vivo and in vitro interaction at the canalicular bile salt export pump (Bsep) in the rat.
    Funk C; Ponelle C; Scheuermann G; Pantze M
    Mol Pharmacol; 2001 Mar; 59(3):627-35. PubMed ID: 11179459
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Morgan RE; Trauner M; van Staden CJ; Lee PH; Ramachandran B; Eschenberg M; Afshari CA; Qualls CW; Lightfoot-Dunn R; Hamadeh HK
    Toxicol Sci; 2010 Dec; 118(2):485-500. PubMed ID: 20829430
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Morgan RE; van Staden CJ; Chen Y; Kalyanaraman N; Kalanzi J; Dunn RT; Afshari CA; Hamadeh HK
    Toxicol Sci; 2013 Nov; 136(1):216-41. PubMed ID: 23956101
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytochrome P450-mediated hepatic metabolism of new fluorescent substrates in cats and dogs.
    van Beusekom CD; Schipper L; Fink-Gremmels J
    J Vet Pharmacol Ther; 2010 Dec; 33(6):519-27. PubMed ID: 21062303
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Two compartment model of diazepam biotransformation in an organotypical culture of primary human hepatocytes.
    Acikgöz A; Karim N; Giri S; Schmidt-Heck W; Bader A
    Toxicol Appl Pharmacol; 2009 Jan; 234(2):179-91. PubMed ID: 18983865
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions.
    Fattinger K; Funk C; Pantze M; Weber C; Reichen J; Stieger B; Meier PJ
    Clin Pharmacol Ther; 2001 Apr; 69(4):223-31. PubMed ID: 11309550
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Biotransformation of diazepam in a clinically relevant flat membrane bioreactor model using primary porcine hepatocytes.
    Maringka M; Giri S; Nieber K; Acikgöz A; Bader A
    Fundam Clin Pharmacol; 2011 Jun; 25(3):343-53. PubMed ID: 20618872
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of membrane cholesterol on BSEP/Bsep activity: species specificity studies for substrates and inhibitors.
    Kis E; Ioja E; Nagy T; Szente L; Herédi-Szabó K; Krajcsi P
    Drug Metab Dispos; 2009 Sep; 37(9):1878-86. PubMed ID: 19520776
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vitro exploration of potential mechanisms of toxicity of the human hepatotoxic drug fenclozic acid.
    Rodrigues AV; Rollison HE; Martin S; Sarda S; Schulz-Utermoehl T; Stahl S; Gustafsson F; Eakins J; Kenna JG; Wilson ID
    Arch Toxicol; 2013 Aug; 87(8):1569-79. PubMed ID: 23609606
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of bosentan, an endothelin receptor antagonist, on bile salt export pump and multidrug resistance-associated protein 2.
    Mano Y; Usui T; Kamimura H
    Biopharm Drug Dispos; 2007 Jan; 28(1):13-8. PubMed ID: 17061295
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Warner DJ; Chen H; Cantin LD; Kenna JG; Stahl S; Walker CL; Noeske T
    Drug Metab Dispos; 2012 Dec; 40(12):2332-41. PubMed ID: 22961681
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Disruption of BSEP Function in HepaRG Cells Alters Bile Acid Disposition and Is a Susceptive Factor to Drug-Induced Cholestatic Injury.
    Qiu X; Zhang Y; Liu T; Shen H; Xiao Y; Bourner MJ; Pratt JR; Thompson DC; Marathe P; Humphreys WG; Lai Y
    Mol Pharm; 2016 Apr; 13(4):1206-16. PubMed ID: 26910619
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Basal efflux of bile acids contributes to drug-induced bile acid-dependent hepatocyte toxicity in rat sandwich-cultured hepatocytes.
    Susukida T; Sekine S; Ogimura E; Aoki S; Oizumi K; Horie T; Ito K
    Toxicol In Vitro; 2015 Oct; 29(7):1454-63. PubMed ID: 26055650
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biliary excretion of pravastatin and taurocholate in rats with bile salt export pump (Bsep) impairment.
    Cheng Y; Freeden C; Zhang Y; Abraham P; Shen H; Wescott D; Humphreys WG; Gan J; Lai Y
    Biopharm Drug Dispos; 2016 Jul; 37(5):276-86. PubMed ID: 27059119
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Aleo MD; Luo Y; Swiss R; Bonin PD; Potter DM; Will Y
    Hepatology; 2014 Sep; 60(3):1015-22. PubMed ID: 24799086
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparative pharmacokinetic profile of cimicoxib in dogs and cats after IV administration.
    Schneider M; Dron F; Cuinet E; Woehrlé F
    Vet J; 2021 Apr; 270():105625. PubMed ID: 33641805
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.