319 related articles for article (PubMed ID: 26680364)
1. Synthesis and Biochemical Evaluation of 3-Phenoxy-1,4-diarylazetidin-2-ones as Tubulin-Targeting Antitumor Agents.
Greene TF; Wang S; Greene LM; Nathwani SM; Pollock JK; Malebari AM; McCabe T; Twamley B; O'Boyle NM; Zisterer DM; Meegan MJ
J Med Chem; 2016 Jan; 59(1):90-113. PubMed ID: 26680364
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
Zhou P; Liang Y; Zhang H; Jiang H; Feng K; Xu P; Wang J; Wang X; Ding K; Luo C; Liu M; Wang Y
Eur J Med Chem; 2018 Jan; 144():817-842. PubMed ID: 29306206
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors.
Liang Y; Zhang M; Zhou P; Liu M; Li J; Wang Y
Bioorg Chem; 2021 Oct; 115():105239. PubMed ID: 34399321
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
Romagnoli R; Baraldi PG; Carrion MD; Cara CL; Cruz-Lopez O; Preti D; Tolomeo M; Grimaudo S; Di Cristina A; Zonta N; Balzarini J; Brancale A; Sarkar T; Hamel E
Bioorg Med Chem; 2008 May; 16(10):5367-76. PubMed ID: 18440234
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and biological evaluation of 1,4-diaryl-2-azetidinones as specific anticancer agents: activation of adenosine monophosphate activated protein kinase and induction of apoptosis.
Tripodi F; Pagliarin R; Fumagalli G; Bigi A; Fusi P; Orsini F; Frattini M; Coccetti P
J Med Chem; 2012 Mar; 55(5):2112-24. PubMed ID: 22329561
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
Romagnoli R; Baraldi PG; Pavani MG; Tabrizi MA; Preti D; Fruttarolo F; Piccagli L; Jung MK; Hamel E; Borgatti M; Gambari R
J Med Chem; 2006 Jun; 49(13):3906-15. PubMed ID: 16789746
[TBL] [Abstract][Full Text] [Related]
7. Bifunctional chiral selenium-containing 1,4-diarylazetidin-2-ones with potent antitumor activities by disrupting tubulin polymerization and inducing reactive oxygen species production.
Tang H; Liang Y; Cheng J; Ding K; Wang Y
Eur J Med Chem; 2021 Oct; 221():113531. PubMed ID: 34044345
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of 1-phenyl-1,2,3,4-dihydroisoquinoline compounds as tubulin polymerization inhibitors.
Zheng CH; Chen J; Liu J; Zhou XT; Liu N; Shi D; Huang JJ; Lv JG; Zhu J; Zhou YJ
Arch Pharm (Weinheim); 2012 Jun; 345(6):454-62. PubMed ID: 22415658
[TBL] [Abstract][Full Text] [Related]
9. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
Romagnoli R; Kimatrai Salvador M; Schiaffino Ortega S; Baraldi PG; Oliva P; Baraldi S; Lopez-Cara LC; Brancale A; Ferla S; Hamel E; Balzarini J; Liekens S; Mattiuzzo E; Basso G; Viola G
Eur J Med Chem; 2018 Jan; 143():683-698. PubMed ID: 29220790
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agents.
O'Boyle NM; Carr M; Greene LM; Bergin O; Nathwani SM; McCabe T; Lloyd DG; Zisterer DM; Meegan MJ
J Med Chem; 2010 Dec; 53(24):8569-84. PubMed ID: 21080725
[TBL] [Abstract][Full Text] [Related]
11. β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells.
Malebari AM; Fayne D; Nathwani SM; O'Connell F; Noorani S; Twamley B; O'Boyle NM; O'Sullivan J; Zisterer DM; Meegan MJ
Eur J Med Chem; 2020 Mar; 189():112050. PubMed ID: 31954879
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
Wang G; Li C; He L; Lei K; Wang F; Pu Y; Yang Z; Cao D; Ma L; Chen J; Sang Y; Liang X; Xiang M; Peng A; Wei Y; Chen L
Bioorg Med Chem; 2014 Apr; 22(7):2060-79. PubMed ID: 24629450
[TBL] [Abstract][Full Text] [Related]
13. Synthesis, evaluation and structural studies of antiproliferative tubulin-targeting azetidin-2-ones.
O'Boyle NM; Greene LM; Bergin O; Fichet JB; McCabe T; Lloyd DG; Zisterer DM; Meegan MJ
Bioorg Med Chem; 2011 Apr; 19(7):2306-25. PubMed ID: 21397510
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis and antiproliferative activity of the new conjugates of E7010 and resveratrol as tubulin polymerization inhibitors.
Kamal A; Ashraf M; Basha ST; Ali Hussaini SM; Singh S; Vishnuvardhan MV; Kiran B; Sridhar B
Org Biomol Chem; 2016 Jan; 14(4):1382-94. PubMed ID: 26676480
[TBL] [Abstract][Full Text] [Related]
15. Synthesis, biological evaluation, and molecular modelling of new naphthalene-chalcone derivatives as potential anticancer agents on MCF-7 breast cancer cells by targeting tubulin colchicine binding site.
Wang G; Liu W; Gong Z; Huang Y; Li Y; Peng Z
J Enzyme Inhib Med Chem; 2020 Dec; 35(1):139-144. PubMed ID: 31724435
[TBL] [Abstract][Full Text] [Related]
16. Design and synthesis of (2-(phenylamino)thieno[3,2-d]pyrimidin-4-yl)(3,4,5-trimethoxyphenyl)methanone analogues as potent anti-tubulin polymerization agents.
Tian C; Chen X; Zhang Z; Wang X; Liu J
Eur J Med Chem; 2019 Dec; 183():111679. PubMed ID: 31541870
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents.
Liu Y; Wei D; Zhao Y; Cheng W; Lu Y; Ma Y; Li X; Han C; Wei Y; Cao H; Zhao C
Bioorg Med Chem; 2012 Nov; 20(21):6285-95. PubMed ID: 23022053
[TBL] [Abstract][Full Text] [Related]
18. Structure-based virtual screening of novel tubulin inhibitors and their characterization as anti-mitotic agents.
Kim ND; Park ES; Kim YH; Moon SK; Lee SS; Ahn SK; Yu DY; No KT; Kim KH
Bioorg Med Chem; 2010 Oct; 18(19):7092-100. PubMed ID: 20810285
[TBL] [Abstract][Full Text] [Related]
19. (Z)-1-aryl-3-arylamino-2-propen-1-ones, highly active stimulators of tubulin polymerization: synthesis, structure-activity relationship (SAR), tubulin polymerization, and cell growth inhibition studies.
Reddy MV; Akula B; Cosenza SC; Lee CM; Mallireddigari MR; Pallela VR; Subbaiah DR; Udofa A; Reddy EP
J Med Chem; 2012 Jun; 55(11):5174-87. PubMed ID: 22587519
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological evaluation of 1,2,3-triazole linked aminocombretastatin conjugates as mitochondrial mediated apoptosis inducers.
Kamal A; Shaik B; Nayak VL; Nagaraju B; Kapure JS; Shaheer Malik M; Shaik TB; Prasad B
Bioorg Med Chem; 2014 Oct; 22(19):5155-67. PubMed ID: 25192811
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
