BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

320 related articles for article (PubMed ID: 26681807)

  • 1. AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease.
    Vázquez-Manrique RP; Farina F; Cambon K; Dolores Sequedo M; Parker AJ; Millán JM; Weiss A; Déglon N; Neri C
    Hum Mol Genet; 2016 Mar; 25(6):1043-58. PubMed ID: 26681807
    [TBL] [Abstract][Full Text] [Related]  

  • 2. AMPK-α1 functions downstream of oxidative stress to mediate neuronal atrophy in Huntington's disease.
    Ju TC; Chen HM; Chen YC; Chang CP; Chang C; Chern Y
    Biochim Biophys Acta; 2014 Sep; 1842(9):1668-80. PubMed ID: 24946181
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nuclear translocation of AMPK-alpha1 potentiates striatal neurodegeneration in Huntington's disease.
    Ju TC; Chen HM; Lin JT; Chang CP; Chang WC; Kang JJ; Sun CP; Tao MH; Tu PH; Chang C; Dickson DW; Chern Y
    J Cell Biol; 2011 Jul; 194(2):209-27. PubMed ID: 21768291
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain.
    Lim NK; Hung LW; Pang TY; Mclean CA; Liddell JR; Hilton JB; Li QX; White AR; Hannan AJ; Crouch PJ
    Hum Mol Genet; 2014 Aug; 23(15):4051-63. PubMed ID: 24634145
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitogen- and stress-activated protein kinase-1 deficiency is involved in expanded-huntingtin-induced transcriptional dysregulation and striatal death.
    Roze E; Betuing S; Deyts C; Marcon E; Brami-Cherrier K; Pagès C; Humbert S; Mérienne K; Caboche J
    FASEB J; 2008 Apr; 22(4):1083-93. PubMed ID: 18029446
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metformin Protects Cells from Mutant Huntingtin Toxicity Through Activation of AMPK and Modulation of Mitochondrial Dynamics.
    Jin J; Gu H; Anders NM; Ren T; Jiang M; Tao M; Peng Q; Rudek MA; Duan W
    Neuromolecular Med; 2016 Dec; 18(4):581-592. PubMed ID: 27225841
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pramipexole reduces soluble mutant huntingtin and protects striatal neurons through dopamine D3 receptors in a genetic model of Huntington's disease.
    Luis-Ravelo D; Estévez-Silva H; Barroso-Chinea P; Afonso-Oramas D; Salas-Hernández J; Rodríguez-Núñez J; Acevedo-Arozena A; Marcellino D; González-Hernández T
    Exp Neurol; 2018 Jan; 299(Pt A):137-147. PubMed ID: 29056363
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nemo-like kinase reduces mutant huntingtin levels and mitigates Huntington's disease.
    Jiang M; Zhang X; Liu H; LeBron J; Alexandris A; Peng Q; Gu H; Yang F; Li Y; Wang R; Hou Z; Arbez N; Ren Q; Dong JL; Whela E; Wang R; Ratovitski T; Troncoso JC; Mori S; Ross CA; Lim J; Duan W
    Hum Mol Genet; 2020 May; 29(8):1340-1352. PubMed ID: 32242231
    [TBL] [Abstract][Full Text] [Related]  

  • 9. AMPK activation regulates neuronal structure in developing hippocampal neurons.
    Ramamurthy S; Chang E; Cao Y; Zhu J; Ronnett GV
    Neuroscience; 2014 Feb; 259():13-24. PubMed ID: 24295634
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel BAC Mouse Model of Huntington's Disease with 225 CAG Repeats Exhibits an Early Widespread and Stable Degenerative Phenotype.
    Wegrzynowicz M; Bichell TJ; Soares BD; Loth MK; McGlothan JS; Mori S; Alikhan FS; Hua K; Coughlin JM; Holt HK; Jetter CS; Pomper MG; Osmand AP; Guilarte TR; Bowman AB
    J Huntingtons Dis; 2015; 4(1):17-36. PubMed ID: 26333255
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington's disease.
    Farina F; Lambert E; Commeau L; Lejeune FX; Roudier N; Fonte C; Parker JA; Boddaert J; Verny M; Baulieu EE; Neri C
    Sci Rep; 2017 Jun; 7(1):4014. PubMed ID: 28638078
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Alterations in STriatal-Enriched protein tyrosine Phosphatase expression, activation, and downstream signaling in early and late stages of the YAC128 Huntington's disease mouse model.
    Gladding CM; Fan J; Zhang LY; Wang L; Xu J; Li EH; Lombroso PJ; Raymond LA
    J Neurochem; 2014 Jul; 130(1):145-59. PubMed ID: 24588402
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutant huntingtin reduction in astrocytes slows disease progression in the BACHD conditional Huntington's disease mouse model.
    Wood TE; Barry J; Yang Z; Cepeda C; Levine MS; Gray M
    Hum Mol Genet; 2019 Feb; 28(3):487-500. PubMed ID: 30312396
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of AMP-activated protein kinase α (AMPKα) by doxorubicin accentuates genotoxic stress and cell death in mouse embryonic fibroblasts and cardiomyocytes: role of p53 and SIRT1.
    Wang S; Song P; Zou MH
    J Biol Chem; 2012 Mar; 287(11):8001-12. PubMed ID: 22267730
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nature and cause of mitochondrial dysfunction in Huntington's disease: focusing on huntingtin and the striatum.
    Oliveira JM
    J Neurochem; 2010 Jul; 114(1):1-12. PubMed ID: 20403078
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease.
    Liu KY; Shyu YC; Barbaro BA; Lin YT; Chern Y; Thompson LM; James Shen CK; Marsh JL
    Hum Mol Genet; 2015 Mar; 24(6):1602-16. PubMed ID: 25398943
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum.
    Saavedra A; García-Martínez JM; Xifró X; Giralt A; Torres-Peraza JF; Canals JM; Díaz-Hernández M; Lucas JJ; Alberch J; Pérez-Navarro E
    Cell Death Differ; 2010 Feb; 17(2):324-35. PubMed ID: 19745829
    [TBL] [Abstract][Full Text] [Related]  

  • 18. AMP-activated protein kinase enhances the expression of muscle-specific ubiquitin ligases despite its activation of IGF-1/Akt signaling in C2C12 myotubes.
    Tong JF; Yan X; Zhu MJ; Du M
    J Cell Biochem; 2009 Oct; 108(2):458-68. PubMed ID: 19639604
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Twist1 Plays an Anti-apoptotic Role in Mutant Huntingtin Expression Striatal Progenitor Cells.
    Jen WP; Chen HM; Lin YS; Chern Y; Lee YC
    Mol Neurobiol; 2020 Mar; 57(3):1688-1703. PubMed ID: 31813126
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CGS21680 attenuates symptoms of Huntington's disease in a transgenic mouse model.
    Chou SY; Lee YC; Chen HM; Chiang MC; Lai HL; Chang HH; Wu YC; Sun CN; Chien CL; Lin YS; Wang SC; Tung YY; Chang C; Chern Y
    J Neurochem; 2005 Apr; 93(2):310-20. PubMed ID: 15816854
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.