BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1235 related articles for article (PubMed ID: 26683872)

  • 1. Established Stem Cell Model of Spinal Muscular Atrophy Is Applicable in the Evaluation of the Efficacy of Thyrotropin-Releasing Hormone Analog.
    Ohuchi K; Funato M; Kato Z; Seki J; Kawase C; Tamai Y; Ono Y; Nagahara Y; Noda Y; Kameyama T; Ando S; Tsuruma K; Shimazawa M; Hara H; Kaneko H
    Stem Cells Transl Med; 2016 Feb; 5(2):152-63. PubMed ID: 26683872
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Edaravone is a candidate agent for spinal muscular atrophy: In vitro analysis using a human induced pluripotent stem cells-derived disease model.
    Ando S; Funato M; Ohuchi K; Kameyama T; Inagaki S; Seki J; Kawase C; Tsuruma K; Shimazawa M; Kaneko H; Hara H
    Eur J Pharmacol; 2017 Nov; 814():161-168. PubMed ID: 28826912
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modeling the differential phenotypes of spinal muscular atrophy with high-yield generation of motor neurons from human induced pluripotent stem cells.
    Lin X; Li JJ; Qian WJ; Zhang QJ; Wang ZF; Lu YQ; Dong EL; He J; Wang N; Ma LX; Chen WJ
    Oncotarget; 2017 Jun; 8(26):42030-42042. PubMed ID: 28159932
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular Atrophy.
    Hor JH; Soh ES; Tan LY; Lim VJW; Santosa MM; Winanto ; Ho BX; Fan Y; Soh BS; Ng SY
    Cell Death Dis; 2018 Oct; 9(11):1100. PubMed ID: 30368521
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacologically induced mouse model of adult spinal muscular atrophy to evaluate effectiveness of therapeutics after disease onset.
    Feng Z; Ling KK; Zhao X; Zhou C; Karp G; Welch EM; Naryshkin N; Ratni H; Chen KS; Metzger F; Paushkin S; Weetall M; Ko CP
    Hum Mol Genet; 2016 Mar; 25(5):964-75. PubMed ID: 26758873
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Astrocyte-produced miR-146a as a mediator of motor neuron loss in spinal muscular atrophy.
    Sison SL; Patitucci TN; Seminary ER; Villalon E; Lorson CL; Ebert AD
    Hum Mol Genet; 2017 Sep; 26(17):3409-3420. PubMed ID: 28637335
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Seamless Genetic Conversion of SMN2 to SMN1 via CRISPR/Cpf1 and Single-Stranded Oligodeoxynucleotides in Spinal Muscular Atrophy Patient-Specific Induced Pluripotent Stem Cells.
    Zhou M; Hu Z; Qiu L; Zhou T; Feng M; Hu Q; Zeng B; Li Z; Sun Q; Wu Y; Liu X; Wu L; Liang D
    Hum Gene Ther; 2018 Nov; 29(11):1252-1263. PubMed ID: 29598153
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Loganin possesses neuroprotective properties, restores SMN protein and activates protein synthesis positive regulator Akt/mTOR in experimental models of spinal muscular atrophy.
    Tseng YT; Chen CS; Jong YJ; Chang FR; Lo YC
    Pharmacol Res; 2016 Sep; 111():58-75. PubMed ID: 27241020
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Protective Effects of Levetiracetam on a Human iPSCs-Derived Spinal Muscular Atrophy Model.
    Ando S; Funato M; Ohuchi K; Inagaki S; Sato A; Seki J; Kawase C; Saito T; Nishio H; Nakamura S; Shimazawa M; Kaneko H; Hara H
    Neurochem Res; 2019 Jul; 44(7):1773-1779. PubMed ID: 31102025
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Notch Signaling Mediates Astrocyte Abnormality in Spinal Muscular Atrophy Model Systems.
    Ohuchi K; Funato M; Yoshino Y; Ando S; Inagaki S; Sato A; Kawase C; Seki J; Saito T; Nishio H; Nakamura S; Shimazawa M; Kaneko H; Hara H
    Sci Rep; 2019 Mar; 9(1):3701. PubMed ID: 30842449
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A SMN2 Splicing Modifier Rescues the Disease Phenotypes in an In Vitro Human Spinal Muscular Atrophy Model.
    Son YS; Choi K; Lee H; Kwon O; Jung KB; Cho S; Baek J; Son B; Kang SM; Kang M; Yoon J; Shen H; Lee S; Oh JH; Lee HA; Lee MO; Cho HS; Jung CR; Kim J; Cho S; Son MY
    Stem Cells Dev; 2019 Apr; 28(7):438-453. PubMed ID: 30667343
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Spinal muscular atrophy phenotype is ameliorated in human motor neurons by SMN increase via different novel RNA therapeutic approaches.
    Nizzardo M; Simone C; Dametti S; Salani S; Ulzi G; Pagliarani S; Rizzo F; Frattini E; Pagani F; Bresolin N; Comi G; Corti S
    Sci Rep; 2015 Jun; 5():11746. PubMed ID: 26123042
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Abnormal mitochondrial transport and morphology as early pathological changes in human models of spinal muscular atrophy.
    Xu CC; Denton KR; Wang ZB; Zhang X; Li XJ
    Dis Model Mech; 2016 Jan; 9(1):39-49. PubMed ID: 26586529
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Antisense Transcript SMN-AS1 Regulates SMN Expression and Is a Novel Therapeutic Target for Spinal Muscular Atrophy.
    d'Ydewalle C; Ramos DM; Pyles NJ; Ng SY; Gorz M; Pilato CM; Ling K; Kong L; Ward AJ; Rubin LL; Rigo F; Bennett CF; Sumner CJ
    Neuron; 2017 Jan; 93(1):66-79. PubMed ID: 28017471
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Normalization of Patient-Identified Plasma Biomarkers in SMNĪ”7 Mice following Postnatal SMN Restoration.
    Arnold WD; Duque S; Iyer CC; Zaworski P; McGovern VL; Taylor SJ; von Herrmann KM; Kobayashi DT; Chen KS; Kolb SJ; Paushkin SV; Burghes AH
    PLoS One; 2016; 11(12):e0167077. PubMed ID: 27907033
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy.
    Kannan A; Jiang X; He L; Ahmad S; Gangwani L
    Brain; 2020 Jan; 143(1):69-93. PubMed ID: 31828288
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Astrocytes influence the severity of spinal muscular atrophy.
    Rindt H; Feng Z; Mazzasette C; Glascock JJ; Valdivia D; Pyles N; Crawford TO; Swoboda KJ; Patitucci TN; Ebert AD; Sumner CJ; Ko CP; Lorson CL
    Hum Mol Genet; 2015 Jul; 24(14):4094-102. PubMed ID: 25911676
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SMN deficiency does not induce oxidative stress in SMA iPSC-derived astrocytes or motor neurons.
    Patitucci TN; Ebert AD
    Hum Mol Genet; 2016 Feb; 25(3):514-23. PubMed ID: 26643950
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Decreased Motor Neuron Support by SMA Astrocytes due to Diminished MCP1 Secretion.
    Martin JE; Nguyen TT; Grunseich C; Nofziger JH; Lee PR; Fields D; Fischbeck KH; Foran E
    J Neurosci; 2017 May; 37(21):5309-5318. PubMed ID: 28450545
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Investigation of New Morpholino Oligomers to Increase Survival Motor Neuron Protein Levels in Spinal Muscular Atrophy.
    Ramirez A; Crisafulli SG; Rizzuti M; Bresolin N; Comi GP; Corti S; Nizzardo M
    Int J Mol Sci; 2018 Jan; 19(1):. PubMed ID: 29316633
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 62.