BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 26686468)

  • 1. Enhanced targeting of mitochondrial peroxide defense by the combined use of thiosemicarbazones and inhibitors of thioredoxin reductase.
    Myers CR
    Free Radic Biol Med; 2016 Feb; 91():81-92. PubMed ID: 26686468
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The iron-chelating drug triapine causes pronounced mitochondrial thiol redox stress.
    Myers JM; Antholine WE; Zielonka J; Myers CR
    Toxicol Lett; 2011 Mar; 201(2):130-6. PubMed ID: 21195754
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation.
    Cox AG; Brown KK; Arner ES; Hampton MB
    Biochem Pharmacol; 2008 Oct; 76(9):1097-109. PubMed ID: 18789312
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of reductase systems by 2-AAPA modulates peroxiredoxin oxidation and mitochondrial function in A172 glioblastoma cells.
    de Souza LF; Schmitz AE; da Silva LCS; de Oliveira KA; Nedel CB; Tasca CI; de Bem AF; Farina M; Dafre AL
    Toxicol In Vitro; 2017 Aug; 42():273-280. PubMed ID: 28461233
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitochondrial respiratory chain involvement in peroxiredoxin 3 oxidation by phenethyl isothiocyanate and auranofin.
    Brown KK; Cox AG; Hampton MB
    FEBS Lett; 2010 Mar; 584(6):1257-62. PubMed ID: 20176019
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Redox activation of Fe(III)-thiosemicarbazones and Fe(III)-bleomycin by thioredoxin reductase: specificity of enzymatic redox centers and analysis of reactive species formation by ESR spin trapping.
    Myers JM; Cheng Q; Antholine WE; Kalyanaraman B; Filipovska A; Arnér ES; Myers CR
    Free Radic Biol Med; 2013 Jul; 60():183-94. PubMed ID: 23485585
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The effects of acrolein on peroxiredoxins, thioredoxins, and thioredoxin reductase in human bronchial epithelial cells.
    Myers CR; Myers JM
    Toxicology; 2009 Mar; 257(1-2):95-104. PubMed ID: 19135121
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metal complexes of 3-(4-bromophenyl)-1-pyridin-2-ylprop-2-en-1-one thiosemicarbazone: cytotoxic activity and investigation on the mode of action of the gold(III) complex.
    Sâmia LB; Parrilha GL; Da Silva JG; Ramos JP; Souza-Fagundes EM; Castelli S; Vutey V; Desideri A; Beraldo H
    Biometals; 2016 Jun; 29(3):515-26. PubMed ID: 27091443
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gold(I) complexes with thiosemicarbazones: cytotoxicity against human tumor cell lines and inhibition of thioredoxin reductase activity.
    Lessa JA; Guerra JC; de Miranda LF; Romeiro CF; Da Silva JG; Mendes IC; Speziali NL; Souza-Fagundes EM; Beraldo H
    J Inorg Biochem; 2011 Dec; 105(12):1729-39. PubMed ID: 22005449
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Methemoglobin formation by triapine, di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone (Dp44mT), and other anticancer thiosemicarbazones: identification of novel thiosemicarbazones and therapeutics that prevent this effect.
    Quach P; Gutierrez E; Basha MT; Kalinowski DS; Sharpe PC; Lovejoy DB; Bernhardt PV; Jansson PJ; Richardson DR
    Mol Pharmacol; 2012 Jul; 82(1):105-14. PubMed ID: 22508546
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Disabling Mitochondrial Peroxide Metabolism via Combinatorial Targeting of Peroxiredoxin 3 as an Effective Therapeutic Approach for Malignant Mesothelioma.
    Cunniff B; Newick K; Nelson KJ; Wozniak AN; Beuschel S; Leavitt B; Bhave A; Butnor K; Koenig A; Chouchani ET; James AM; Haynes AC; Lowther WT; Murphy MP; Shukla A; Heintz NH
    PLoS One; 2015; 10(5):e0127310. PubMed ID: 26011724
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The potent and novel thiosemicarbazone chelators di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone and 2-benzoylpyridine-4,4-dimethyl-3-thiosemicarbazone affect crucial thiol systems required for ribonucleotide reductase activity.
    Yu Y; Suryo Rahmanto Y; Hawkins CL; Richardson DR
    Mol Pharmacol; 2011 Jun; 79(6):921-31. PubMed ID: 21389104
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitochondrial peroxiredoxin 3 is rapidly oxidized in cells treated with isothiocyanates.
    Brown KK; Eriksson SE; Arnér ES; Hampton MB
    Free Radic Biol Med; 2008 Aug; 45(4):494-502. PubMed ID: 18501718
    [TBL] [Abstract][Full Text] [Related]  

  • 14. FOXM1-Induced PRX3 Regulates Stemness and Survival of Colon Cancer Cells via Maintenance of Mitochondrial Function.
    Song IS; Jeong YJ; Jeong SH; Heo HJ; Kim HK; Bae KB; Park YH; Kim SU; Kim JM; Kim N; Ko KS; Rhee BD; Han J
    Gastroenterology; 2015 Oct; 149(4):1006-16.e9. PubMed ID: 26091938
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Detoxification of Mitochondrial Oxidants and Apoptotic Signaling Are Facilitated by Thioredoxin-2 and Peroxiredoxin-3 during Hyperoxic Injury.
    Forred BJ; Daugaard DR; Titus BK; Wood RR; Floen MJ; Booze ML; Vitiello PF
    PLoS One; 2017; 12(1):e0168777. PubMed ID: 28045936
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fluorescent silver(I) and gold(I)-N-heterocyclic carbene complexes with cytotoxic properties: mechanistic insights.
    Citta A; Schuh E; Mohr F; Folda A; Massimino ML; Bindoli A; Casini A; Rigobello MP
    Metallomics; 2013 Aug; 5(8):1006-15. PubMed ID: 23661165
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gold(I) carbene complexes causing thioredoxin 1 and thioredoxin 2 oxidation as potential anticancer agents.
    Schuh E; Pflüger C; Citta A; Folda A; Rigobello MP; Bindoli A; Casini A; Mohr F
    J Med Chem; 2012 Jun; 55(11):5518-28. PubMed ID: 22621714
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dual targeting of the thioredoxin and glutathione antioxidant systems in malignant B cells: a novel synergistic therapeutic approach.
    Kiebala M; Skalska J; Casulo C; Brookes PS; Peterson DR; Hilchey SP; Dai Y; Grant S; Maggirwar SB; Bernstein SH
    Exp Hematol; 2015 Feb; 43(2):89-99. PubMed ID: 25448488
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Peroxiredoxin 3 is a redox-dependent target of thiostrepton in malignant mesothelioma cells.
    Newick K; Cunniff B; Preston K; Held P; Arbiser J; Pass H; Mossman B; Shukla A; Heintz N
    PLoS One; 2012; 7(6):e39404. PubMed ID: 22761781
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Peroxiredoxin 3 levels regulate a mitochondrial redox setpoint in malignant mesothelioma cells.
    Cunniff B; Wozniak AN; Sweeney P; DeCosta K; Heintz NH
    Redox Biol; 2014; 3():79-87. PubMed ID: 25462069
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.